New York Knicks vs Philadelphia 76ers Prediction & Picks - NBA

USA - NBA

New York Knicks
10/20/26 19:00
Philadelphia 76ers

Prediction:

 

Philadelphia 76ers +4.5

−108
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 by Matt Lowrimore | in NBA Picks

Tuesday marks the start of the new NBA season, and with that, three games are on the schedule, one of which will include an Eastern Conference matchup between the New York Knicks and the Philadelphia 76ers. Let’s take a look at the match statistics and predictions for this game between the Knicks and 76ers.

Philadelphia enters this game, having finished last season with a record of 45-37. The 76ers had to go through the play-in tournament to claim the #7 seed last season. Despite that, Philadelphia upset Boston in the first round before being swept in the Conference Semifinals against the New York Knicks. Most notably, the 76ers brought in Jaylen Brown and LeBron James in the offseason, which should give them a great chance to compete for a title this season.  

As for New York, they enter this game having finished last season with a record of 53-29. The Knicks are the defending NBA Champions, beating the San Antonio Spurs 4-1. New York brings back the majority of their championship team; however, there is a chance they will not be able to blow out an improved Philadelphia team.

New York Knicks vs Philadelphia 76ers Form

New York Knicks and Philadelphia 76ers Latest Matches

New York Knicks
New York Knicks Latest matches
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 17, 2026 - NBA Summer League

New York Knicks
88 :  110
Dallas Mavericks

Jul 16, 2026 - NBA Summer League

New York Knicks
77 :  87
Golden State Warriors

Jul 13, 2026 - NBA Summer League

New York Knicks
86 :  75
Detroit Pistons

Jul 11, 2026 - NBA Summer League

San Antonio Spurs
70 :  49
New York Knicks

Jul 10, 2026 - NBA Summer League

New York Knicks
65 :  91
Brooklyn Nets

Jun 13, 2026 - NBA

San Antonio Spurs
90 :  94
New York Knicks
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 17, 2026 - NBA Summer League

New York Knicks
88 :  110
Dallas Mavericks

Jul 16, 2026 - NBA Summer League

New York Knicks
77 :  87
Golden State Warriors

Jul 13, 2026 - NBA Summer League

New York Knicks
86 :  75
Detroit Pistons

Jul 10, 2026 - NBA Summer League

New York Knicks
65 :  91
Brooklyn Nets

Jun 10, 2026 - NBA

New York Knicks
107 :  106
San Antonio Spurs

Jun 8, 2026 - NBA

New York Knicks
111 :  115
San Antonio Spurs
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jul 11, 2026 - NBA Summer League

San Antonio Spurs
70 :  49
New York Knicks

Jun 13, 2026 - NBA

San Antonio Spurs
90 :  94
New York Knicks

Jun 5, 2026 - NBA

San Antonio Spurs
104 :  105
New York Knicks

Jun 3, 2026 - NBA

San Antonio Spurs
95 :  105
New York Knicks

May 25, 2026 - NBA

Cleveland Cavaliers
93 :  130
New York Knicks

May 23, 2026 - NBA

Cleveland Cavaliers
108 :  121
New York Knicks
Philadelphia 76ers
Philadelphia 76ers Latest matches
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 18, 2026 - NBA Summer League

Milwaukee Bucks
96 :  94
Philadelphia 76ers

Jul 15, 2026 - NBA Summer League

Philadelphia 76ers
92 :  99
Orlando Magic

Jul 14, 2026 - NBA Summer League

Houston Rockets
90 :  64
Philadelphia 76ers

Jul 11, 2026 - NBA Summer League

Philadelphia 76ers
100 :  93
Indiana Pacers

Jul 9, 2026 - NBA Summer League

Philadelphia 76ers
101 :  93
Detroit Pistons

May 10, 2026 - NBA

Philadelphia 76ers
114 :  144
New York Knicks
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 15, 2026 - NBA Summer League

Philadelphia 76ers
92 :  99
Orlando Magic

Jul 11, 2026 - NBA Summer League

Philadelphia 76ers
100 :  93
Indiana Pacers

Jul 9, 2026 - NBA Summer League

Philadelphia 76ers
101 :  93
Detroit Pistons

May 10, 2026 - NBA

Philadelphia 76ers
114 :  144
New York Knicks

May 8, 2026 - NBA

Philadelphia 76ers
94 :  108
New York Knicks

Apr 30, 2026 - NBA

Philadelphia 76ers
106 :  93
Boston Celtics
W W L L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 18, 2026 - NBA Summer League

Milwaukee Bucks
96 :  94
Philadelphia 76ers

Jul 14, 2026 - NBA Summer League

Houston Rockets
90 :  64
Philadelphia 76ers

May 6, 2026 - NBA

New York Knicks
108 :  102
Philadelphia 76ers

May 4, 2026 - NBA

New York Knicks
137 :  98
Philadelphia 76ers

May 2, 2026 - NBA

Boston Celtics
100 :  109
Philadelphia 76ers

Apr 28, 2026 - NBA

Boston Celtics
97 :  113
Philadelphia 76ers

New York Knicks against Philadelphia 76ers : Head to Head (H2H)

New York Knicks

100 %

Philadelphia 76ers

0 %

May 10, 2026 - NBA

Philadelphia 76ers
114 :  144
New York Knicks

May 8, 2026 - NBA

Philadelphia 76ers
94 :  108
New York Knicks

May 6, 2026 - NBA

New York Knicks
108 :  102
Philadelphia 76ers

May 4, 2026 - NBA

New York Knicks
137 :  98
Philadelphia 76ers

Feb 11, 2026 - NBA

Philadelphia 76ers
89 :  138
New York Knicks

Jan 24, 2026 - NBA

Philadelphia 76ers
109 :  112
New York Knicks
New York Knicks vs Philadelphia 76ers Picks

Players list

New York Knicks
New York Knicks
L. Robbins

J. Kayil

D. Jones

P. Dadiet

T. Nickel

Philadelphia 76ers
Philadelphia 76ers
I. Johnson

G. Ayayi

D. Maddox

D. Miles

A. Lyles

Substitutes

New York Knicks
New York Knicks

A. Yuot

W. Johnston

T. Okani

J. Akins

E. Reynolds

O. Sellers

T. Eaglestaff

K. Palek

L. Ware

N. Jourdain

L. Wilson

M. Diawara

Philadelphia 76ers
Philadelphia 76ers
D. Cisse

M. Wilson

T. Fields

J. Campbell

M. Rogers

S. Thomas

N. Townsend

New York Knicks - Philadelphia 76ers Key Points

  1. Philadelphia was 22-19 on the road last season
  2. Philadelphia was 3-5 ATS vs. New York last season (including playoffs)
  3. New York was 30-10 at home last season
  4. New York was 6-2 SU vs. Philadelphia last season (including playoffs)

Our New York Knicks vs Philadelphia 76ers Prediction

New York is the clear favorite in this game; however, Philadelphia looks to be the best betting option. The Knicks had a ton of success against the 76ers last season, going 6-2 SU against them (including the playoffs). Furthermore, the 76ers were just 3-5 ATS against the Knicks. 

That said, this looks to be a much improved Philadelphia side with both LeBron James and Jaylen Brown joining the roster. The likely result for this game is a Knicks win given how good they are at home; however, with the 76ers adding two elite players, our New York Knicks vs. Philadelphia 76ers prediction is: Philadelphia 76ers +4.5.

Prediction:

 

Philadelphia 76ers +4.5

−108
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.