Cleveland Cavaliers vs Philadelphia 76ers Prediction & Picks - NBA
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by Lou Aguila | in NBA Picks
The Cleveland Cavaliers and the Philadelphia 76ers meet for the first time this season on Wednesday at Rocket Arena.
The Sixers are listed as +10.5-point underdogs against the Cavaliers despite parading a 5-2 record through the first two weeks of the season.
Current Form:
Philadelphia suffered its second loss in three games after coming up short against the resurging Chicago Bulls 111-113. Tyrese Maxey dropped 39 points, 5 rebounds, and 5 assists, while Joel Embiid and Kelly Oubre chipped in 20 and 18 points, respectively. The Sixers had an 11-point lead, 95-84, at the end of the first period, but they let Chicago outscore them 29-16 in the payoff period.
After back-to-back losses to Boston 105-125, and Toronto 101-112, the Cavaliers returned to the winner’s circle after downing the Atlanta Hawks 117-109. Donovan Mitchell exploded for 37 points and De’Andre Hunter added 19 points for the short-handed Cavs, who missed All-Star Jarrett Allen, Evan Mobley, and Darius Garland due to injuries. The Cavs improved to 4-3 in the season and 2-1 at home.
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Cleveland Cavaliers vs Philadelphia 76ers Form
Table
| Teams | % | P | W | L | Series |
|---|---|---|---|---|---|
|
8
|
0.634 | 82 | 52 | 30 | 1 |
|
13
|
0.549 | 82 | 45 | 37 | 2 |
Cleveland Cavaliers and Philadelphia 76ers Latest Matches
4/6 (67%)
2/6 (33%)
Nov 5, 2025 - NBA
Nov 2, 2025 - NBA
Oct 31, 2025 - NBA
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3/6 (50%)
3/6 (50%)
Nov 5, 2025 - NBA
Nov 2, 2025 - NBA
Oct 31, 2025 - NBA
Oct 26, 2025 - NBA
Jul 16, 2025 - NBA Summer League
May 13, 2025 - NBA
2/6 (33%)
4/6 (67%)
Oct 29, 2025 - NBA
Oct 27, 2025 - NBA
Oct 24, 2025 - NBA
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Jul 10, 2025 - NBA Summer League
May 11, 2025 - NBA
3/6 (50%)
3/6 (50%)
Nov 5, 2025 - NBA
Nov 4, 2025 - NBA
Nov 2, 2025 - NBA
Oct 31, 2025 - NBA
Oct 28, 2025 - NBA
Oct 27, 2025 - NBA
3/6 (50%)
3/6 (50%)
Oct 31, 2025 - NBA
Oct 27, 2025 - NBA
Oct 25, 2025 - NBA
Jul 16, 2025 - NBA Summer League
Apr 13, 2025 - NBA
Apr 11, 2025 - NBA
4/6 (67%)
2/6 (33%)
Nov 5, 2025 - NBA
Nov 4, 2025 - NBA
Nov 2, 2025 - NBA
Oct 28, 2025 - NBA
Oct 22, 2025 - NBA
Apr 9, 2025 - NBA
Cleveland Cavaliers against Philadelphia 76ers : Head to Head (H2H)
67 %
33 %
Nov 5, 2025 - NBA
Jan 24, 2025 - NBA
Dec 21, 2024 - NBA
Nov 13, 2024 - NBA
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Players list
D. Mitchell
D. Garland
E. Mobley
J. Tyson
T. Maxey
V. Edgecombe
J. Walker
Substitutes
C. Porter
T. Proctor
L. Ball
S. Merrill
N. Tomlin
E. Gordon
H. Sallis
J. Edwards
K. Lowry
Q. Grimes
T. Watford
Cleveland Cavaliers - Philadelphia 76ers Key Points
- Philadelphia is 5-2 SU in its last 7 games.
- Philadelphia is 5-1 ATS in its last 6 games against Cleveland.
- Cleveland is 2-7 ATS in its last 9 games.
- Cleveland is 1-6 ATS in its last 7 games at home.
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Our Cleveland Cavaliers vs Philadelphia 76ers Prediction
Fearless Forecast: The Sixers are an enticing bet to cover the spread with a +10.5-point head start. Philadelphia looks like a playoff contender in the East after its first seven games this season. Tyrese Maxey continues to be a bucket, but he’s getting help from rookie VJ Edgecombe and Kelly Oubre Jr. Joel Embiid is steadily getting back to form after battling with injuries in the past two seasons. The Cavs could get back the service of Darius Garland and Jarrett Allen, but still, I believe the Sixers can go toe-to-toe with the Cavs in this matchup, especially if Maxey, Edgecombe and Embiid deliver strong numbers.
Our betting prediction for the Cleveland Cavaliers vs. the Philadelphia 76ers: the Sixers +10.5 Points
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
