Boston Celtics vs Philadelphia 76ers Prediction & Picks - NBA

USA - NBA

Boston Celtics
10/22/25 19:30
Philadelphia 76ers

Prediction:

 

Boston Celtics to cover -2.5 spread.

-105
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 by Stephen Abiola | in NBA Picks

Boston Celtics and Philadelphia 76ers will start their 2025-26 regular season campaign with a matchup at the TD Garden on Wednesday night. The Celtics will look to reclaim their Eastern Conference crown after losing it to the Cavaliers last season. They bolstered their roster during the offseason with veteran deals for Josh Minott, Chris Boucher, and Luka Garza. Bouncher is the most reliable option and will play a key role in their championship quest this season.

Philadelphia 76ers, meanwhile, had a brutal campaign last season. They had high expectations following the signing of nine-time NBA All-Star forward Paul George as a free agent. However, things didn’t work out as they had wanted, with George and Joel Embiid suffering multiple injuries. Surprisingly, they didn’t make any significant changes during the offseason, with Nick Nurse getting another chance to redeem their fortunes. He’ll pray for an injury-free campaign.

Boston Celtics vs Philadelphia 76ers Form

Table

Teams % P W L Series
4 Boston Celtics
0.683 82 56 26 2
13 Philadelphia 76ers
0.549 82 45 37 2

Boston Celtics and Philadelphia 76ers Latest Matches

Boston Celtics
Boston Celtics Latest matches
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - NBA Summer League

Boston Celtics
101 :  80
Atlanta Hawks

Jul 17, 2025 - NBA Summer League

Los Angeles Lakers
78 :  87
Boston Celtics

Jul 14, 2025 - NBA Summer League

Miami Heat
100 :  96
Boston Celtics

Jul 13, 2025 - NBA Summer League

Boston Celtics
94 :  81
New York Knicks

Jul 11, 2025 - NBA Summer League

Boston Celtics
92 :  78
Memphis Grizzlies

May 16, 2025 - NBA

New York Knicks
119 :  81
Boston Celtics
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2025 - NBA Summer League

Boston Celtics
101 :  80
Atlanta Hawks

Jul 13, 2025 - NBA Summer League

Boston Celtics
94 :  81
New York Knicks

Jul 11, 2025 - NBA Summer League

Boston Celtics
92 :  78
Memphis Grizzlies

May 14, 2025 - NBA

Boston Celtics
127 :  102
New York Knicks

May 7, 2025 - NBA

Boston Celtics
90 :  91
New York Knicks

May 5, 2025 - NBA

Boston Celtics
105 :  108
New York Knicks
W W L L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 17, 2025 - NBA Summer League

Los Angeles Lakers
78 :  87
Boston Celtics

Jul 14, 2025 - NBA Summer League

Miami Heat
100 :  96
Boston Celtics

May 16, 2025 - NBA

New York Knicks
119 :  81
Boston Celtics

May 12, 2025 - NBA

New York Knicks
121 :  113
Boston Celtics

May 10, 2025 - NBA

New York Knicks
93 :  115
Boston Celtics

Apr 27, 2025 - NBA

Orlando Magic
98 :  107
Boston Celtics
Philadelphia 76ers
Philadelphia 76ers Latest matches
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 18, 2025 - NBA Summer League

Brooklyn Nets
83 :  87
Philadelphia 76ers

Jul 16, 2025 - NBA Summer League

Philadelphia 76ers
90 :  82
Dallas Mavericks

Jul 15, 2025 - NBA Summer League

Washington Wizards
58 :  74
Philadelphia 76ers

Jul 12, 2025 - NBA Summer League

Philadelphia 76ers
94 :  96
Charlotte Hornets

Jul 10, 2025 - NBA Summer League

Philadelphia 76ers
70 :  111
San Antonio Spurs

Jul 8, 2025 - NBA Summer League

Philadelphia 76ers
91 :  90
Memphis Grizzlies
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 16, 2025 - NBA Summer League

Philadelphia 76ers
90 :  82
Dallas Mavericks

Jul 12, 2025 - NBA Summer League

Philadelphia 76ers
94 :  96
Charlotte Hornets

Jul 10, 2025 - NBA Summer League

Philadelphia 76ers
70 :  111
San Antonio Spurs

Jul 8, 2025 - NBA Summer League

Philadelphia 76ers
91 :  90
Memphis Grizzlies

Jul 7, 2025 - NBA Summer League

Philadelphia 76ers
78 :  89
Oklahoma City Thunder

Apr 13, 2025 - NBA

Philadelphia 76ers
102 :  122
Chicago Bulls
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 18, 2025 - NBA Summer League

Brooklyn Nets
83 :  87
Philadelphia 76ers

Jul 15, 2025 - NBA Summer League

Washington Wizards
58 :  74
Philadelphia 76ers

Jul 5, 2025 - NBA Summer League

Utah Jazz
93 :  89
Philadelphia 76ers

Apr 9, 2025 - NBA

Washington Wizards
103 :  122
Philadelphia 76ers

Apr 7, 2025 - NBA

Miami Heat
117 :  105
Philadelphia 76ers

Apr 1, 2025 - NBA

New York Knicks
105 :  91
Philadelphia 76ers

Boston Celtics against Philadelphia 76ers : Head to Head (H2H)

Boston Celtics

83 %

Philadelphia 76ers

17 %

Mar 6, 2025 - NBA

Boston Celtics
123 :  105
Philadelphia 76ers

Feb 20, 2025 - NBA

Philadelphia 76ers
104 :  124
Boston Celtics

Feb 2, 2025 - NBA

Philadelphia 76ers
110 :  118
Boston Celtics

Dec 25, 2024 - NBA

Boston Celtics
114 :  118
Philadelphia 76ers

Feb 27, 2024 - NBA

Boston Celtics
117 :  99
Philadelphia 76ers

Dec 1, 2023 - NBA

Boston Celtics
125 :  119
Philadelphia 76ers

Players list

Boston Celtics
Boston Celtics
N. Queta J. Brown S. Hauser

D. White

P. Pritchard

Philadelphia 76ers
Philadelphia 76ers
J. Embiid K. Oubre Jr.

T. Maxey

V. Edgecombe

D. Barlow

Substitutes

Boston Celtics
Boston Celtics
C. Boucher L. Garza

B. Scheierman

M. Shulga

H. Gonzalez

A. Simons

J. Minott

J. Walsh

X. Tillman

Philadelphia 76ers
Philadelphia 76ers
A. Bona J. Broome A. Drummond

J. Edwards

Q. Grimes

E. Gordon

K. Lowry

J. Walker

Boston Celtics - Philadelphia 76ers Key Points

  1. Boston Celtics won their last six home games.
  2. Boston Celtics won five of their last six games.
  3. Philadelphia 76ers lost five of their last six matches.
  4. Boston Celtics are 6-4 ATS in their last 10 matches against the 76ers.

Our Boston Celtics vs Philadelphia 76ers Prediction

Boston will want to start the season strongly on Wednesday night. Historically, they have enjoyed excellent results against the 76ers, winning in four of their last five meetings. They had a strong postseason run, winning three of their four matches, including a 138-107 win over the Cavaliers. However, both teams could miss some important players. Jayson Tatum will sit out for the Celtics with a long-term Achilles injury. Jaylen brown is also doubtful with a hamstring injury. As for the 76ers, Embiid should be fit to start, although Paul George could miss out with a knee injury. They should keep it close, although we expect Boston to start the season with a win.

Our prediction for Boston Celtics vs Philadelphia 76ers: Boston Celtics to cover -2.5 spread.

Prediction:

 

Boston Celtics to cover -2.5 spread.

-105
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Boston Celtics vs Philadelphia 76ers Picks