Orlando City SC vs Columbus Crew Prediction & Picks - Major League Soccer

Prediction published on 10/4/25, 4:16 PM  by Erik Gibbs in Major League Soccer Picks

Orlando City and Columbus Crew square off this weekend in a pivotal clash as the Eastern Conference regular season nears its conclusion. With all nine playoff spots officially locked, the focus now shifts to seeding, and this match could play a huge role in determining which side avoids being forced into the dreaded wild-card round. Both teams still have plenty to play for, and the margins are extremely thin.

Orlando enter the contest holding the final automatic qualification place, but their grip on that position remains far from secure. Recent form has been mixed, with two draws in their last three matches. However, their 1-1 draw with FC Cincinnati, one of the strongest sides in the league, was seen as a positive step and a morale boost heading into the closing stretch.

History is also slightly in their favor, with Orlando defeating Columbus 3-1 in July, a result that snapped a three-game losing run against the Crew. That victory showcased their ability to press with intensity, win challenges in midfield, and quickly turn defensive stops into offensive chances. Under Oscar Pareja, Orlando’s identity has become one of energy and rapid transitions, an approach that could once again unsettle Columbus.

The Crew, by contrast, have struggled to generate momentum. Winless in their last three MLS matches, they were well beaten by the Chicago Fire last weekend in a performance that raised questions about their sharpness and urgency. Despite nearly half of the possession, Columbus created little, mustering only one shot on target across 90 minutes.