St. Louis Cardinals vs Athletics Prediction & Picks - MLB

Prediction published on 9/3/25, 4:37 PM  by Travis Pulver | Modified on 1/13/26 at 9:16 AM in MLB Picks

The Athletics will face the Cardinals in the final game of a three-game series at Busch Stadium in St. Louis, MO. First Pitch for this AL vs. NL matchup is scheduled for 7:45 p.m. EST. St. Louis took charge in the first game of the series on Monday, winning easily, 11-3. But Game Two yesterday was a tighter, more competitive, low-scoring affair that ended with the A’s coming out ahead, 2-1.

The Cardinals will turn to Matthew Liberatore to start the day on the mound. Liberatore has gone 6-11 in 25 starts with a 4.32 ERA, 1.32 WHIP, and a .269 OBA. He’s gone 4-5 in 11 starts at home with a 4.55 ERA and a .283 OBA. In his last three home starts, he failed to make it out of the fourth inning. As for the Athletics, the A’s will give Jeffrey Springs the ball to start the day. Springs has gone 10-9 in 26 starts (28 appearances)  with a 4.17 ERA, 1.19 WHIP, and a .232 OBA. He’s been at his best when on the road, where he is 5-5 with a 3.66 ERA in 14 starts (15 appearances) with a .217 OBA.