Houston Astros vs Athletics Prediction & Picks - MLB

USA - MLB

Houston Astros
6/5/26 20:10
Athletics

Prediction:

 

Over 9 Total Runs

-104
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 by Matt Lowrimore | in MLB Picks

All 30 teams will be in action in the MLB on Friday, which includes an American League West matchup between the Houston Astros and the Athletics. Let’s take a look at the match statistics and predictions for this game between the Astros and the Athletics.

The Athletics enter this game hovering just under .500 and, as a result, are in second place in the AL West. They are scheduled to start Jack Perkins against the Astros in Game 1 of this series. Perkins has mainly come out of the bullpen this season and will be making his first start of the season in this game. Further, Perkins has an ERA of 5.46 and has not excelled on the road or at home in his relief appearances this season.

As for Houston, they enter this game well below .500 and are in fourth place in the AL West. The Astros are set to start Peter Lambert, who has a record of 4-4 and an ERA of 3.77. Additionally, Lambert has not been consistent when pitching at home, opening the door for the Athletics to have success offensively.

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Houston Astros vs Athletics Form

Table

Teams Pts P W L
19 Athletics
0.477 65 31 34
22 Houston Astros
0.448 67 30 37

Houston Astros and Athletics Latest Matches

Houston Astros
Houston Astros Latest matches
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jun 4, 2026 - MLB

Houston Astros
1 :  5
Pittsburgh Pirates

Jun 3, 2026 - MLB

Houston Astros
11 :  9
Pittsburgh Pirates

Jun 2, 2026 - MLB

Houston Astros
6 :  10
Pittsburgh Pirates

May 31, 2026 - MLB

Houston Astros
0 :  2
Milwaukee Brewers

May 30, 2026 - MLB

Houston Astros
9 :  2
Milwaukee Brewers

May 29, 2026 - MLB

Houston Astros
4 :  5
Milwaukee Brewers
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jun 4, 2026 - MLB

Houston Astros
1 :  5
Pittsburgh Pirates

Jun 3, 2026 - MLB

Houston Astros
11 :  9
Pittsburgh Pirates

Jun 2, 2026 - MLB

Houston Astros
6 :  10
Pittsburgh Pirates

May 31, 2026 - MLB

Houston Astros
0 :  2
Milwaukee Brewers

May 30, 2026 - MLB

Houston Astros
9 :  2
Milwaukee Brewers

May 29, 2026 - MLB

Houston Astros
4 :  5
Milwaukee Brewers
W W W L W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 28, 2026 - MLB

Texas Rangers
1 :  5
Houston Astros

May 27, 2026 - MLB

Texas Rangers
3 :  4
Houston Astros

May 26, 2026 - MLB

Texas Rangers
10 :  7
Houston Astros

May 25, 2026 - MLB

Texas Rangers
0 :  9
Houston Astros

May 24, 2026 - MLB

Chicago Cubs
5 :  8
Houston Astros

May 23, 2026 - MLB

Chicago Cubs
0 :  3
Houston Astros
Athletics
Athletics Latest matches
L W L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 4, 2026 - MLB

Chicago Cubs
7 :  6
Athletics

Jun 3, 2026 - MLB

Chicago Cubs
4 :  5
Athletics

Jun 2, 2026 - MLB

Chicago Cubs
1 :  2
Athletics

May 31, 2026 - MLB

Athletics
8 :  13
New York Yankees

May 30, 2026 - MLB

Athletics
6 :  4
New York Yankees

May 29, 2026 - MLB

Athletics
2 :  8
New York Yankees
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 31, 2026 - MLB

Athletics
8 :  13
New York Yankees

May 30, 2026 - MLB

Athletics
6 :  4
New York Yankees

May 29, 2026 - MLB

Athletics
2 :  8
New York Yankees

May 27, 2026 - MLB

Athletics
1 :  9
Seattle Mariners

May 26, 2026 - MLB

Athletics
1 :  4
Seattle Mariners

May 25, 2026 - MLB

Athletics
2 :  9
Seattle Mariners
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 4, 2026 - MLB

Chicago Cubs
7 :  6
Athletics

Jun 3, 2026 - MLB

Chicago Cubs
4 :  5
Athletics

Jun 2, 2026 - MLB

Chicago Cubs
1 :  2
Athletics

May 24, 2026 - MLB

San Diego Padres
2 :  5
Athletics

May 23, 2026 - MLB

San Diego Padres
2 :  0
Athletics

May 22, 2026 - MLB

San Diego Padres
7 :  3
Athletics

Houston Astros against Athletics : Head to Head (H2H)

Houston Astros

33 %

Athletics

67 %

Apr 5, 2026 - MLB

Athletics
12 :  10
Houston Astros

Apr 4, 2026 - MLB

Athletics
0 :  11
Houston Astros

Apr 3, 2026 - MLB

Athletics
11 :  4
Houston Astros

Sep 25, 2025 - MLB

Athletics
5 :  11
Houston Astros

Sep 24, 2025 - MLB

Athletics
6 :  0
Houston Astros

Sep 23, 2025 - MLB

Athletics
5 :  1
Houston Astros

Houston Astros - Athletics Key Points

  1. Jack Perkins has an ERA of 5.46 this season
  2. Jack Perkins has an ERA of 4.63 on the road this season
  3. Peter Lambert has an ERA of 3.77 this season
  4. Peter Lambert has an ERA of 4.20 at home this season
Up to $200 to bet on Houston Astros - Athletics! 

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Our Houston Astros vs Athletics Prediction

The Athletics are the small favorite in this game; however, the over looks to be the best betting option. As discussed, both starters in this matchup have been average to below-average so far this season. In seven relief appearances on the road for Perkins, he has allowed eight runs (six earned) over 11.2 innings. Lambert, on the other hand, has made five home starts this season, where he has allowed 14 earned runs over 30.0 innings. 

Despite their poor record, the Astros are 10th in runs per game, while the Athletics are 20th in the same category. Because of this, our Houston Astros vs Athletics prediction is: Over 9 Total Runs.

Prediction:

 

Over 9 Total Runs

-104
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Houston Astros vs Athletics Picks