Arizona Diamondbacks vs Athletics Prediction & Picks - MLB

USA - MLB

Arizona Diamondbacks
7/21/26 21:40
Athletics

Prediction:

 

Kohl Drake Strikeouts - 5+

+181
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 by Edgar Jibran in MLB Picks

The second game of the MLB series between the Athletics and the Arizona Diamondbacks will take place this Tuesday night, and it’s a crucial game for the D’Backs after losing the first game of the series. In this regard, it’s worth noting that Arizona only has a two-game advantage over the San Diego Padres in the NL West Division, so they cannot afford to lose this series against the Athletics.

With this in mind, the Athletics will put their trust in Jack Perkins, whose performance has been disappointing this season, as he has allowed more than 3 earned runs in four of his last five starts. Also, he allowed at least 1 home run in four of those games. Considering this, it makes sense for him to have a 2W-5L record this season.

Meanwhile, the Arizona Diamondbacks just announced Kohl Drake as their starting pitcher, it being worth noting that this will be his first appearance of the season with the major team. Given this, he’s expected to approach this game with great motivation, but also with significant pressure after allowing a 6.92 earned run average in the minor leagues with the Reno Aces this season.

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Arizona Diamondbacks vs Athletics Form

Table

Teams Pts P W L
14 Arizona Diamondbacks
0.51 100 51 49
25 Athletics
0.43 100 43 57

Arizona Diamondbacks and Athletics Latest Matches

Arizona Diamondbacks
Arizona Diamondbacks Latest matches
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 20, 2026 - MLB

Arizona Diamondbacks
2 :  5
Athletics

Jul 19, 2026 - MLB

Arizona Diamondbacks
8 :  7
St. Louis Cardinals

Jul 18, 2026 - MLB

Arizona Diamondbacks
5 :  3
St. Louis Cardinals

Jul 17, 2026 - MLB

Arizona Diamondbacks
4 :  5
St. Louis Cardinals

Jul 12, 2026 - MLB

Los Angeles Dodgers
3 :  5
Arizona Diamondbacks

Jul 11, 2026 - MLB

Los Angeles Dodgers
2 :  9
Arizona Diamondbacks
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 20, 2026 - MLB

Arizona Diamondbacks
2 :  5
Athletics

Jul 19, 2026 - MLB

Arizona Diamondbacks
8 :  7
St. Louis Cardinals

Jul 18, 2026 - MLB

Arizona Diamondbacks
5 :  3
St. Louis Cardinals

Jul 17, 2026 - MLB

Arizona Diamondbacks
4 :  5
St. Louis Cardinals

Jul 5, 2026 - MLB

Arizona Diamondbacks
2 :  3
Milwaukee Brewers

Jul 4, 2026 - MLB

Arizona Diamondbacks
4 :  3
Milwaukee Brewers
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 12, 2026 - MLB

Los Angeles Dodgers
3 :  5
Arizona Diamondbacks

Jul 11, 2026 - MLB

Los Angeles Dodgers
2 :  9
Arizona Diamondbacks

Jul 10, 2026 - MLB

Los Angeles Dodgers
3 :  9
Arizona Diamondbacks

Jul 9, 2026 - MLB

San Diego Padres
1 :  3
Arizona Diamondbacks

Jul 8, 2026 - MLB

San Diego Padres
10 :  4
Arizona Diamondbacks

Jul 7, 2026 - MLB

San Diego Padres
4 :  1
Arizona Diamondbacks
Athletics
Athletics Latest matches
L L L W L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jul 20, 2026 - MLB

Arizona Diamondbacks
2 :  5
Athletics

Jul 19, 2026 - MLB

Athletics
2 :  5
Washington Nationals

Jul 18, 2026 - MLB

Athletics
15 :  1
Washington Nationals

Jul 17, 2026 - MLB

Athletics
4 :  23
Washington Nationals

Jul 12, 2026 - MLB

Chicago White Sox
9 :  1
Athletics

Jul 11, 2026 - MLB

Chicago White Sox
1 :  0
Athletics
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Jul 19, 2026 - MLB

Athletics
2 :  5
Washington Nationals

Jul 18, 2026 - MLB

Athletics
15 :  1
Washington Nationals

Jul 17, 2026 - MLB

Athletics
4 :  23
Washington Nationals

Jul 5, 2026 - MLB

Athletics
8 :  9
Miami Marlins

Jul 4, 2026 - MLB

Athletics
2 :  7
Miami Marlins

Jul 3, 2026 - MLB

Athletics
5 :  12
Miami Marlins
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Jul 20, 2026 - MLB

Arizona Diamondbacks
2 :  5
Athletics

Jul 12, 2026 - MLB

Chicago White Sox
9 :  1
Athletics

Jul 11, 2026 - MLB

Chicago White Sox
1 :  0
Athletics

Jul 10, 2026 - MLB

Chicago White Sox
14 :  1
Athletics

Jul 9, 2026 - MLB

Detroit Tigers
4 :  1
Athletics

Jul 8, 2026 - MLB

Detroit Tigers
6 :  1
Athletics

Arizona Diamondbacks against Athletics : Head to Head (H2H)

Arizona Diamondbacks

50 %

Athletics

50 %

Jul 20, 2026 - MLB

Arizona Diamondbacks
2 :  5
Athletics

Mar 11, 2026 - MLB Spring Training

Arizona Diamondbacks
3 :  13
Athletics

Mar 4, 2026 - MLB Spring Training

Athletics
1 :  3
Arizona Diamondbacks

Aug 3, 2025 - MLB

Athletics
4 :  6
Arizona Diamondbacks

Aug 2, 2025 - MLB

Athletics
2 :  7
Arizona Diamondbacks

Aug 1, 2025 - MLB

Athletics
5 :  1
Arizona Diamondbacks
Arizona Diamondbacks vs Athletics Picks

Arizona Diamondbacks - Athletics Key Points

  1. The Athletics saw Jack Perkins allow 4 or more hits in his last five straight starting games.
  2. The Arizona Diamondbacks have great expectations for Kohl Drake, who made his season debut in the MiLB with a five-inning no-hit game.
  3. The Athletics had Jeff McNeil as one of the best performers in the first game of the series against the D’Backs, as he allowed 2 runs batted in with one hit.
  4. The Arizona Diamondbacks also had a man of the match in the first game of the series, as Ketel Marte partially tied the game with a two-run home run.
Up to $150 to bet on Arizona Diamondbacks - Athletics! 

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Our Arizona Diamondbacks vs Athletics Prediction

Considering all these factors, this matchup is expected to be entertaining, especially since there aren't very positive expectations around both starting pitchers. However, Kohl Drake is expected to be highly motivated in his MLB debut at home, having a fantastic opportunity to make a good first impression on the D’Backs’ fans.

To conclude, while the Athletics managed to win the first game of the series, they could face difficulties against a debutant pitcher like Drake, whose style is practically unknown to all the batters in the league. Therefore, the pick for the Athletics – Arizona Diamondbacks is: Kohl Drake Strikeouts – 5+!

Prediction:

 

Kohl Drake Strikeouts - 5+

+181
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.