Minnesota Twins vs New York Yankees Prediction & Picks - MLB

Prediction published on 9/14/26, 5:16 AM  by Sarah Lou Jones | Modified on 9/14/26 at 5:34 AM in MLB Picks

American Central meets American East as Minnesota Twins take on New York Yankees in the first of their three-game MLB series. Yankees head into this one in good form with a Last 10 record of 7-3. The Twins, on the other hand, hold a L10 of 3-7, making this an intriguing match-up. Twins has lost their previous two series 2-1, first against Detroit Tigers and then against Cleveland Guardians. In contrast, the Bronze Bombers have won their last two, 3-0 against Colorado Rockies and 2-1 against rivals New York Mets.

Twins has won the last two meetings between the two teams, with scorelines of 11-4 and 6-1 clinching the series win last time out. The Yankees are favorites this time out, but for our prediction we're focusing on the Totals market.

Both sides tend to score and concede plenty of runs of late. In fact, Yankees 2-0 against Mets was the first time in 14 games that fewer than six runs have been hit in games featuring The Pinstripers. We think they'll be plenty scored in this one, too.