Houston Astros vs New York Yankees Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Travis Pulver | in MLB Picks
After going 2-1 in Cleveland, the Houston Astros (10-16, 7-6 Home) will hope they can keep the good times rolling when they open a three-game weekend series with the New York Yankees at home. First Pitch for Game One is scheduled for tonight at 8:10 p.m. EST at Daikin Park in Houston, TX, with coverage provided by MLB.TV.
Most of the season has been a struggle for the Astros, as their pitching has been atrocious. But it was pretty decent overall in Cleveland. In the series finale on Thursday, Peter Lambert threw six innings of three-hit, shutout ball for the Astros, with the bullpen throwing the other three and maintaining the shutout and only giving up two hits.
Houston will start the night with Lance McCullers Jr. on the mound tonight. McCullers Jr. has a 1-1 record in four starts with a 6.20 ERA and a 1.38 WHIP. In 47 at-bats vs. the Yankees lineup, he has held them to a .255 BA. As for the Yankees, Will Warren will get the start. He is 2-0 in five starts with a 2.49 ERA and a 1.11 WHIP. This will be just his second start away from home this season.
Limited Offer. Currently at Fanatics
Houston Astros vs New York Yankees Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
5
|
0.585 | 82 | 48 | 34 |
|
18
|
0.482 | 85 | 41 | 44 |
Houston Astros and New York Yankees Latest Matches
2/6 (33%)
4/6 (67%)
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 20, 2026 - MLB
Apr 19, 2026 - MLB
Apr 18, 2026 - MLB
Apr 17, 2026 - MLB
2/6 (33%)
4/6 (67%)
Apr 19, 2026 - MLB
Apr 18, 2026 - MLB
Apr 17, 2026 - MLB
Apr 16, 2026 - MLB
Apr 15, 2026 - MLB
Apr 14, 2026 - MLB
2/6 (33%)
4/6 (67%)
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 20, 2026 - MLB
Apr 13, 2026 - MLB
Apr 12, 2026 - MLB
Apr 11, 2026 - MLB
6/6 (100%)
0/6 (0%)
Apr 23, 2026 - MLB
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 19, 2026 - MLB
Apr 18, 2026 - MLB
Apr 17, 2026 - MLB
4/6 (67%)
2/6 (33%)
Apr 19, 2026 - MLB
Apr 18, 2026 - MLB
Apr 17, 2026 - MLB
Apr 16, 2026 - MLB
Apr 15, 2026 - MLB
Apr 14, 2026 - MLB
3/6 (50%)
3/6 (50%)
Apr 23, 2026 - MLB
Apr 22, 2026 - MLB
Apr 21, 2026 - MLB
Apr 12, 2026 - MLB
Apr 11, 2026 - MLB
Apr 10, 2026 - MLB
Houston Astros against New York Yankees : Head to Head (H2H)
50 %
50 %
Sep 4, 2025 - MLB
Sep 3, 2025 - MLB
Sep 2, 2025 - MLB
Aug 10, 2025 - MLB
Aug 9, 2025 - MLB
Aug 8, 2025 - MLB
Houston Astros - New York Yankees Key Points
- New York leads the all-time series vs. Houston, 57-49.
- The Yankees have gone 14-6 vs. Houston the last three seasons and 9-1 in Houston.
- Daikin Park is tied for the fourth most home runs this season with 38; the Yankees have hit ten in the last week.
- Betting Public: 79% of moneyline tickets and 83% of the handle are on the Yankees.
Limited Offer. Currently at Fanatics
Our Houston Astros vs New York Yankees Prediction
New York should win this game. Will Warren is a solid pitcher, and the lineup has been crushing the ball. At one time, McCullers Jr. was a fan favorite, but he has been inconsistent for some time now. He might turn in a great game and keep Houston competitive in this one, or he might not, and the Yankees will blow the Astros right out of the water. So, out of caution, I’m going with the moneyline over the run line (just in case Houston has a good game).
Our New York vs. Houston: Yankees ML
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
