Houston Astros vs New York Yankees Prediction & Picks - MLB

Prediction published on 9/3/25, 4:43 PM  by Lou Aguila | Modified on 2/3/26 at 8:35 AM in MLB Picks

The New York Yankees look to stay hot, as they gun for their 9th win in 10 games in Wednesday’s Game 2 against the Houston Astros at Daikin Park.

Holding an 8-2 record against the spread in their last 10 games, the Yankees are a hot pick on the run line. Their odds to cover a -1.5 run handicap are currently listed at +128, which means a profit of $128 for every $100 bet if they beat the Astros by at least two runs.

Current Form:

Behind an 8-1 surge in their last 9 games, the Yankees have improved their record to 77-61 and moved within 2.5 games of the AL East leaders, the Toronto Blue Jays, who carry an 80-59 record. The Yankees are averaging 6.1 runs per game in their last five games while maintaining an outstanding 1.67 ERA in the stretch.

The Astros have dropped three of their last four games, including the 1-7 loss to the Yankees on Tuesday. They are still the top team in the AL West with a 76-63 record, though they are still facing pressure from their closest trailers, the 73-66 Seattle Mariners, who are trailing them by only three games. Houston’s ERA over its last five games is still a solid 3.40. The problem is that the Astros’ offense has only averaged 2.5 runs per game over the five-game stretch.