Houston Astros vs New York Yankees Prediction & Picks - MLB

Prediction published on 9/2/25, 4:22 PM  by Lou Aguila | Modified on 2/3/26 at 8:35 AM in MLB Picks

A payout of $150 for every $100 bet is up for grabs when the New York Yankees go for their 8th win in 9 games in Tuesday’s series opener against the Houston Astros at Daikin Park.

The Yankees will walk into Game 1 of a pivotal series with the Astros as -116 favorites on FanDuel. The Bronx Bombers are also listed at -150 on the run line, where they are facing a 1.5-run handicap.

Form in the last five games:

The Yankees are 4-1 in their last five games. To be precise, they had won five games in a row before dropping a 2-3 loss to the White Sox in Sunday’s series finale. Over the last five games, New York has sported elite numbers at the plate and on the mound, averaging 7.0 runs per game on a .244 batting average while commanding a 1.76 ERA.

The Astros are 3-2 in their last five assignments, with the 2 wins coming in the just-concluded four-game series with the LA Angels. Like the Yankees, Houston has produced formidable pitching numbers in their last five games, logging a 2.60 ERA and 1.13 WHIP. Offensively, Houston is a bummer right now. They are averaging only 3.2 runs per game on a .245 batting average over the five-game stretch.