Cleveland Guardians vs New York Yankees Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
4/22/25 18:10
New York Yankees

Prediction:

 

New York Yankees to win.

-111
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 by Stephen Abiola | in MLB Picks

Cleveland Guardians (9-9) versus New York Yankees (12-7) is an American League contest on Tuesday night at Progressive Field. Both teams will seek to maintain momentum in their respective divisions after solid starts. The Guardians are second in the AL Central, just 1.5 games behind the Tigers. They have been exceptional at home this season, losing only once, a record only bettered by the Tigers in the division. The Guardians are in one of the most winnable divisions in the MLB and should be in the playoff conversation in October.

New York Yankees, on the other hand, are off to a flying start in the AL East, sitting on top of the standings with a .632 winning record. They bagged their first road series this season against the Pirates and will be looking to take another away series win against the Rays. The Yankees entered this season with a mix of a veteran core and vibrant young talents, including Austin Wells. They should be in the championship fight this season.

Cleveland Guardians vs New York Yankees Form

Table

Teams Pts P W L
3 New York Yankees
0.58 162 94 68
10 Cleveland Guardians
0.543 162 88 74

Cleveland Guardians and New York Yankees Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 21, 2025 - MLB

Cleveland Guardians
6 :  4
New York Yankees

Apr 20, 2025 - MLB

Pittsburgh Pirates
4 :  5
Cleveland Guardians

Apr 19, 2025 - MLB

Pittsburgh Pirates
0 :  3
Cleveland Guardians

Apr 18, 2025 - MLB

Pittsburgh Pirates
7 :  10
Cleveland Guardians

Apr 17, 2025 - MLB

Baltimore Orioles
6 :  2
Cleveland Guardians

Apr 16, 2025 - MLB

Baltimore Orioles
9 :  1
Cleveland Guardians
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 21, 2025 - MLB

Cleveland Guardians
6 :  4
New York Yankees

Apr 13, 2025 - MLB

Cleveland Guardians
2 :  4
Kansas City Royals

Apr 12, 2025 - MLB

Cleveland Guardians
6 :  3
Kansas City Royals

Apr 11, 2025 - MLB

Cleveland Guardians
7 :  0
Kansas City Royals

Apr 10, 2025 - MLB

Cleveland Guardians
6 :  1
Chicago White Sox

Apr 9, 2025 - MLB

Cleveland Guardians
3 :  2
Chicago White Sox
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Pittsburgh Pirates
4 :  5
Cleveland Guardians

Apr 19, 2025 - MLB

Pittsburgh Pirates
0 :  3
Cleveland Guardians

Apr 18, 2025 - MLB

Pittsburgh Pirates
7 :  10
Cleveland Guardians

Apr 17, 2025 - MLB

Baltimore Orioles
6 :  2
Cleveland Guardians

Apr 16, 2025 - MLB

Baltimore Orioles
9 :  1
Cleveland Guardians

Apr 15, 2025 - MLB

Baltimore Orioles
3 :  6
Cleveland Guardians
New York Yankees
New York Yankees Latest matches
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 21, 2025 - MLB

Cleveland Guardians
6 :  4
New York Yankees

Apr 20, 2025 - MLB

Tampa Bay Rays
0 :  4
New York Yankees

Apr 18, 2025 - MLB

Tampa Bay Rays
0 :  1
New York Yankees

Apr 17, 2025 - MLB

Tampa Bay Rays
3 :  6
New York Yankees

Apr 16, 2025 - MLB

New York Yankees
4 :  3
Kansas City Royals

Apr 15, 2025 - MLB

New York Yankees
4 :  2
Kansas City Royals
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 16, 2025 - MLB

New York Yankees
4 :  3
Kansas City Royals

Apr 15, 2025 - MLB

New York Yankees
4 :  2
Kansas City Royals

Apr 14, 2025 - MLB

New York Yankees
4 :  1
Kansas City Royals

Apr 13, 2025 - MLB

New York Yankees
4 :  5
San Francisco Giants

Apr 12, 2025 - MLB

New York Yankees
8 :  4
San Francisco Giants

Apr 11, 2025 - MLB

New York Yankees
1 :  9
San Francisco Giants
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 21, 2025 - MLB

Cleveland Guardians
6 :  4
New York Yankees

Apr 20, 2025 - MLB

Tampa Bay Rays
0 :  4
New York Yankees

Apr 18, 2025 - MLB

Tampa Bay Rays
0 :  1
New York Yankees

Apr 17, 2025 - MLB

Tampa Bay Rays
3 :  6
New York Yankees

Apr 9, 2025 - MLB

Detroit Tigers
3 :  4
New York Yankees

Apr 8, 2025 - MLB

Detroit Tigers
5 :  0
New York Yankees

Cleveland Guardians against New York Yankees : Head to Head (H2H)

Cleveland Guardians

33 %

New York Yankees

67 %

Apr 21, 2025 - MLB

Cleveland Guardians
6 :  4
New York Yankees

Oct 19, 2024 - MLB

Cleveland Guardians
2 :  5
New York Yankees

Oct 18, 2024 - MLB

Cleveland Guardians
6 :  8
New York Yankees

Oct 17, 2024 - MLB

Cleveland Guardians
7 :  5
New York Yankees

Oct 15, 2024 - MLB

New York Yankees
6 :  3
Cleveland Guardians

Oct 14, 2024 - MLB

New York Yankees
5 :  2
Cleveland Guardians

Cleveland Guardians - New York Yankees Key Points

  1. The Yankees are 4-1 in their last five matches.
  2. The total runs went over in three of the last four Cleveland vs New York games.
  3. The Guardians are 4-6 ATS in their last 10 games.
  4. The Yankees are 6-1 ATS in their last seven meetings with the Guardians.

Our Cleveland Guardians vs New York Yankees Prediction

Both Cleveland and New York have been solid this season, so we expect some fireworks. The Yankees will enter this matchup with a psychological advantage after winning 11 of their last 15 meetings with the Guardians. 

Interestingly, they have lost only once to the Guardians in their previous seven clashes. The Yankees are also the better side at the moment, scoring an average of 4.4 runs in the last five games, whereas the Guardians have an average of 3.4 runs. In the pitching department, the Guardians allowed an average of five runs in as many games, while the Yankees averaged 4.4 runs. The Yankees are clearly the better side. Our prediction for Cleveland Guardians vs New York Yankees: New York Yankees to win.

Prediction:

 

New York Yankees to win.

-111
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Cleveland Guardians vs New York Yankees Picks