Chicago White Sox vs New York Yankees Prediction & Picks - MLB

Prediction published on 8/29/25, 4:40 PM  by Lou Aguila | Modified on 9/1/25 at 1:10 AM in MLB Picks

The New York Yankees will attempt to secure their sixth straight victory in Friday’s Game 2 against the Chicago White Sox at Rate Field.

The Yankees, who are 7-3 in their last 10 meetings with the White Sox, are booked as -224 favorites against the worst team in the American League. New York’s offense has been flying over its last five games, averaging 9.4 runs per game on a .309 BA. The Yankees have also benefitted from strong mound performances by Luis Gil, Carlos Rodon, and Max Fried this week, posting a 2.00 ERA in the 5-game stretch.

The White Sox have lost three games in a row, including Thursday’s 4-10 loss to the Yankees. At 48-86, Chicago remains the worst team in the American League , though they have shown flashes of potential sparingly this season. Over their last five games, the White Sox have pitched a 4.47 ERA and averaged 5.0 runs per game on a .256 batting average.