Baltimore Orioles vs New York Yankees Prediction & Picks - MLB

Prediction published on 9/20/25, 3:39 PM  by Travis Pulver | Modified on 2/10/26 at 6:20 AM in MLB Picks

The Orioles will try to make it two in a row today when they host the New York Yankees at Camden Yards in Baltimore at 7:05 p.m. EST (broadcast on the MLB Network). New York dominated Game 1 of the series on Thursday, 7-0, but the Orioles won yesterday's contest behind a solid outing by Trevor Rogers (6 innings, 1 hit, 7 strikeouts, 0 earned runs) 4-2.

Baltimore is going with Tomoyuki Sugano to start the day. Sugano is 10-8 this season with 28 starts, a 4.39 ERA, 1.32 WHIP, and .273 OBA. He has pitched well at home, going 7-4 in 14 starts with a 4.31 ERA and .266 OBA. He’s had starts against the Yankees this season, holding them to five hits in five innings with no earned runs on April 28 and giving up seven hits and three runs in 3 2/3 inning on June 20. As for New York, the Yankees will have Carlos Rodon start. Rodon has gone 16-9 in 31 starts with a 3.11 ERA, 1.07 WHIP, and .189 OBA. In 17 road starts, he has gone 7-5 with a 3.32 ERA and .220 OBA. He won his only start vs. the Orioles this season on April 29, giving up two hits and two runs in six innings.