LSU Tigers vs Mississippi State Bulldogs Prediction & Picks - NCAA
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by Matt Lowrimore | in NCAA Picks
Another huge game on the Week 7 College Football Saturday slate will feature a matchup in the SEC between the #16-ranked Mississippi State Bulldogs and the #22-ranked LSU Tigers. Let’s take a look at the match statistics and predictions for this game between the Bulldogs and the Tigers.
Mississippi State enters this game with a record of 4-1 and 2-1 in the SEC. The Bulldogs are coming off their bye week and most recently lost to Alabama in Week 5 by a score of 56-23. Mississippi State was clearly overmatched in this game, as they had 302 yards of offense while allowing 483 yards. Despite this setback, the Bulldogs have still been a pleasant surprise this season and have a good chance of bouncing back with a competitive game against an overrated LSU side.
As for LSU, they enter this game with a record of 4-2 and 1-2 in the SEC. The Tigers are coming off a 35-34 overtime upset loss to Kentucky in Week 6. LSU managed to total 410 yards of offense, but their defense once again struggled, allowing 401 yards. The Tigers' first season with Lane Kiffin as their head coach has not gone as expected, and with that, there is plenty of reason to believe they will continue to struggle.
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LSU Tigers vs Mississippi State Bulldogs Form
Table
LSU Tigers and Mississippi State Bulldogs Latest Matches
4/6 (67%)
2/6 (33%)
Oct 10, 2026 - NCAA
Oct 3, 2026 - NCAA
Sep 26, 2026 - NCAA
Sep 19, 2026 - NCAA
Sep 12, 2026 - NCAA
Sep 5, 2026 - NCAA
6/6 (100%)
0/6 (0%)
Oct 3, 2026 - NCAA
Sep 26, 2026 - NCAA
Sep 12, 2026 - NCAA
Sep 5, 2026 - NCAA
Nov 22, 2025 - NCAA
Nov 15, 2025 - NCAA
0/6 (0%)
6/6 (100%)
Oct 10, 2026 - NCAA
Sep 19, 2026 - NCAA
Dec 27, 2025 - NCAA Division I, FBS, Playoffs
Nov 29, 2025 - NCAA
Nov 8, 2025 - NCAA
Oct 18, 2025 - NCAA
4/6 (67%)
2/6 (33%)
Oct 3, 2026 - NCAA
Sep 26, 2026 - NCAA
Sep 19, 2026 - NCAA
Sep 12, 2026 - NCAA
Sep 5, 2026 - NCAA
Jan 2, 2026 - NCAA Division I, FBS, Playoffs
2/6 (33%)
4/6 (67%)
Oct 3, 2026 - NCAA
Sep 26, 2026 - NCAA
Sep 5, 2026 - NCAA
Jan 2, 2026 - NCAA Division I, FBS, Playoffs
Nov 28, 2025 - NCAA
Nov 8, 2025 - NCAA
3/6 (50%)
3/6 (50%)
Sep 19, 2026 - NCAA
Sep 12, 2026 - NCAA
Nov 15, 2025 - NCAA
Nov 1, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 4, 2025 - NCAA
LSU Tigers - Mississippi State Bulldogs Key Points
- Mississippi State is 4-1 ATS this season
- Mississippi State is averaging 39.0 points per game this season
- LSU is 2-4 ATS this season
- LSU is averaging 42.0 points per game this season
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Our LSU Tigers vs Mississippi State Bulldogs Prediction
LSU is more than a two-touchdown favorite in this game; however, Mississippi State looks to be the best betting option. Through six weeks of this season, the Tigers continue to prove they are not a team that can be trusted. Sure, LSU can beat the mid-major schools, but when playing SEC teams, they have struggled more often than not.
It is fair to point out that both of LSU’s losses have been on the road, and Mississippi State is coming off a blowout loss to Alabama. That said, the Bulldogs still have one of the better quarterbacks in the country, and they have had extra time to prepare for this game.
At the very least, this game should be back and forth; therefore, our Mississippi State Bulldogs vs. LSU Tigers prediction is: Mississippi State Bulldogs +14.5.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.