Ole Miss Rebels vs Oklahoma Sooners Prediction & Picks - NCAA

USA - NCAA

Ole Miss Rebels
10/25/25 12:00
Oklahoma Sooners

Prediction:

 

Ole Miss Rebels +4.5

-105
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 by Matt Lowrimore | in NCAA Picks

One of the top games on the Week 9 college football slate will see the 8th-ranked Ole Miss Rebels take on the 13th-ranked Oklahoma Sooners in the SEC. Let’s take a look at the match statistics and predictions for this game between the Rebels and the Sooners.

Ole Miss enters this game with a record of 6-1 and 3-1 in the SEC. The Rebels most recently lost to the Georgia Bulldogs in Week 8 by a score of 43-35. Ole Miss’ offense had a total of 351 yards, while its defense allowed 510 yards. Quarterback Trinidad Chambliss threw for 263 yards and one touchdown, while also leading the team in rushing with 42 yards and two touchdowns.

As for Oklahoma, they enter this game with a record of 6-1 and 2-1 in the SEC. The Sooners most recently beat the South Carolina Gamecocks in Week 8 by a score of 26-7. Oklahoma’s offense had a total of 319 yards, while its defense allowed 224 yards. Quarterback John Mateer threw for 150 yards and one touchdown, while running back Tory Blaylock led the team in rushing with 101 yards and one touchdown.

Ole Miss Rebels vs Oklahoma Sooners Form

Table

Teams % P W D L
4
Ole Miss Rebels
Ole Miss Rebels
0.875 8 7 0 1
6
Oklahoma Sooners
Oklahoma Sooners
0.75 8 6 0 2

Ole Miss Rebels and Oklahoma Sooners Latest Matches

Ole Miss Rebels
Ole Miss Rebels Latest matches
W W W W W L
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Oct 18, 2025 - NCAA

Ole Miss Rebels
35 :  43
Georgia Bulldogs

Oct 11, 2025 - NCAA

Washington State Cougars
21 :  24
Ole Miss Rebels

Sep 27, 2025 - NCAA

LSU Tigers
19 :  24
Ole Miss Rebels

Sep 20, 2025 - NCAA

Tulane Green Wave
10 :  45
Ole Miss Rebels

Sep 13, 2025 - NCAA

Arkansas Razorbacks
35 :  41
Ole Miss Rebels

Sep 6, 2025 - NCAA

Ole Miss Rebels
30 :  23
Kentucky Wildcats
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Oct 11, 2025 - NCAA

Washington State Cougars
21 :  24
Ole Miss Rebels

Sep 27, 2025 - NCAA

LSU Tigers
19 :  24
Ole Miss Rebels

Sep 20, 2025 - NCAA

Tulane Green Wave
10 :  45
Ole Miss Rebels

Sep 13, 2025 - NCAA

Arkansas Razorbacks
35 :  41
Ole Miss Rebels

Aug 30, 2025 - NCAA

Georgia State Panthers
7 :  63
Ole Miss Rebels

Jan 2, 2025 - NCAA Division I, FBS, Playoffs

Duke Blue Devils
20 :  52
Ole Miss Rebels
W L W L
Victories

1/2 (50%)

Draw

0/2 (0%)

Defeats

1/2 (50%)

Oct 18, 2025 - NCAA

Ole Miss Rebels
35 :  43
Georgia Bulldogs

Sep 6, 2025 - NCAA

Ole Miss Rebels
30 :  23
Kentucky Wildcats
Oklahoma Sooners
Oklahoma Sooners Latest matches
W W W W L W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Oct 18, 2025 - NCAA

Oklahoma Sooners
26 :  7
South Carolina Gamecocks

Oct 11, 2025 - NCAA

Oklahoma Sooners
6 :  23
Texas Longhorns

Oct 4, 2025 - NCAA

Kent State Golden Flashes
0 :  44
Oklahoma Sooners

Sep 20, 2025 - NCAA

Auburn Tigers
17 :  24
Oklahoma Sooners

Sep 13, 2025 - NCAA

Oklahoma Sooners
42 :  3
Temple Owls

Sep 6, 2025 - NCAA

Michigan Wolverines
13 :  24
Oklahoma Sooners
W W W W W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Oct 4, 2025 - NCAA

Kent State Golden Flashes
0 :  44
Oklahoma Sooners

Sep 20, 2025 - NCAA

Auburn Tigers
17 :  24
Oklahoma Sooners

Sep 6, 2025 - NCAA

Michigan Wolverines
13 :  24
Oklahoma Sooners

Aug 30, 2025 - NCAA

Illinois State Redbirds
3 :  35
Oklahoma Sooners

Oct 19, 2024 - NCAA

South Carolina Gamecocks
35 :  9
Oklahoma Sooners

Sep 21, 2024 - NCAA

Tennessee Volunteers
25 :  15
Oklahoma Sooners
L L L W L W
Victories

2/4 (50%)

Draw

0/4 (0%)

Defeats

2/4 (50%)

Oct 18, 2025 - NCAA

Oklahoma Sooners
26 :  7
South Carolina Gamecocks

Oct 11, 2025 - NCAA

Oklahoma Sooners
6 :  23
Texas Longhorns

Sep 13, 2025 - NCAA

Oklahoma Sooners
42 :  3
Temple Owls

Dec 27, 2024 - NCAA Division I, FBS, Playoffs

Oklahoma Sooners
20 :  21
Navy Midshipmen

Ole Miss Rebels - Oklahoma Sooners Key Points

  1. Ole Miss is 2-2 ATS vs the SEC
  2. Ole Miss is averaging 32.5 points per game vs the SEC
  3. Oklahoma is 2-1 ATS vs the SEC
  4. Oklahoma is averaging 18.7 points per game vs the SEC

Our Ole Miss Rebels vs Oklahoma Sooners Prediction

Ole Miss fell from the unbeaten last week when they lost to Georgia, and now face another road test against Oklahoma. The Rebels’ offense torched the Bulldogs for most of the game, but at the same time, their defense could not get off the field. 

Oklahoma, on the other hand, cruised in their game against South Carolina, but their quarterback, John Mateer, still did not have a great performance. 

At this point in the season, picking up a second loss could eliminate either side from the SEC Championship and possibly the College Football Playoffs. While this game is being played in Oklahoma, Ole Miss is sure to make the necessary adjustments from what they saw last week. For that reason, our Ole Miss Rebels vs Oklahoma Sooners prediction is: Ole Miss Rebels +4.5.

Prediction:

 

Ole Miss Rebels +4.5

-105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Ole Miss Rebels vs Oklahoma Sooners Picks