Washington Nationals vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

Washington Nationals
5/6/26 18:45
Minnesota Twins

Prediction:

 

Twins -1.5

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 by Travis Pulver | in MLB Picks

The Washington Nationals (16-20, 4-13 Home) will try to get back on the right side of the scoreboard tonight when they host the Minnesota Twins at Nationals Park in Washington, D.C. First Pitch for this contest is scheduled for 6:45 P.M. EST with coverage provided by MLB.TV.

An offensive explosion carried the Twins to an 11-3 win in a game that saw them record ten hits, including a home run by Byron Buxton in the 8th that made the score 10-3. Taj Bradley got his fourth win of the season after holding the Nationals to four hits and two earned runs while striking out eight in six innings of work.

Washington is giving Miles Mikolas the ball to start the day. Mikolas is having a rough season so far and has yet to record a win in seven starts. He is 0-3 with an 8.23 ERA and a 1.72 WHIP. Of his seven starts, Mikolas has lasted five innings in just one.  

Bailey Ober will get the start for the Twins. Ober is 3-1 in seven starts with a 3.55 ERA and a 1.13 WHIP. He has gone 6+ innings in his last four starts, winning two.

Washington Nationals vs Minnesota Twins Form

Table

Teams Pts P W L
13 Washington Nationals
0.5 84 42 42
22 Minnesota Twins
0.464 84 39 45

Washington Nationals and Minnesota Twins Latest Matches

Washington Nationals
Washington Nationals Latest matches
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 5, 2026 - MLB

Washington Nationals
3 :  11
Minnesota Twins

May 3, 2026 - MLB

Washington Nationals
3 :  2
Milwaukee Brewers

May 2, 2026 - MLB

Washington Nationals
1 :  4
Milwaukee Brewers

May 1, 2026 - MLB

Washington Nationals
1 :  6
Milwaukee Brewers

Apr 30, 2026 - MLB

New York Mets
4 :  5
Washington Nationals

Apr 29, 2026 - MLB

New York Mets
2 :  14
Washington Nationals
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 5, 2026 - MLB

Washington Nationals
3 :  11
Minnesota Twins

May 3, 2026 - MLB

Washington Nationals
3 :  2
Milwaukee Brewers

May 2, 2026 - MLB

Washington Nationals
1 :  4
Milwaukee Brewers

May 1, 2026 - MLB

Washington Nationals
1 :  6
Milwaukee Brewers

Apr 23, 2026 - MLB

Washington Nationals
2 :  7
Atlanta Braves

Apr 22, 2026 - MLB

Washington Nationals
6 :  8
Atlanta Braves
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 30, 2026 - MLB

New York Mets
4 :  5
Washington Nationals

Apr 29, 2026 - MLB

New York Mets
2 :  14
Washington Nationals

Apr 28, 2026 - MLB

New York Mets
8 :  0
Washington Nationals

Apr 26, 2026 - MLB

Chicago White Sox
1 :  2
Washington Nationals

Apr 25, 2026 - MLB

Chicago White Sox
3 :  6
Washington Nationals

Apr 24, 2026 - MLB

Chicago White Sox
5 :  4
Washington Nationals
Minnesota Twins
Minnesota Twins Latest matches
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 5, 2026 - MLB

Washington Nationals
3 :  11
Minnesota Twins

May 3, 2026 - MLB

Minnesota Twins
4 :  3
Toronto Blue Jays

May 2, 2026 - MLB

Minnesota Twins
4 :  11
Toronto Blue Jays

May 1, 2026 - MLB

Minnesota Twins
3 :  7
Toronto Blue Jays

Apr 30, 2026 - MLB

Minnesota Twins
7 :  1
Toronto Blue Jays

Apr 29, 2026 - MLB

Minnesota Twins
3 :  5
Seattle Mariners
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 3, 2026 - MLB

Minnesota Twins
4 :  3
Toronto Blue Jays

May 2, 2026 - MLB

Minnesota Twins
4 :  11
Toronto Blue Jays

May 1, 2026 - MLB

Minnesota Twins
3 :  7
Toronto Blue Jays

Apr 30, 2026 - MLB

Minnesota Twins
7 :  1
Toronto Blue Jays

Apr 29, 2026 - MLB

Minnesota Twins
3 :  5
Seattle Mariners

Apr 28, 2026 - MLB

Minnesota Twins
1 :  7
Seattle Mariners
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 5, 2026 - MLB

Washington Nationals
3 :  11
Minnesota Twins

Apr 26, 2026 - MLB

Tampa Bay Rays
4 :  2
Minnesota Twins

Apr 25, 2026 - MLB

Tampa Bay Rays
6 :  1
Minnesota Twins

Apr 24, 2026 - MLB

Tampa Bay Rays
6 :  2
Minnesota Twins

Apr 23, 2026 - MLB

New York Mets
10 :  8
Minnesota Twins

Apr 22, 2026 - MLB

New York Mets
3 :  2
Minnesota Twins

Washington Nationals against Minnesota Twins : Head to Head (H2H)

Washington Nationals

50 %

Minnesota Twins

50 %

May 5, 2026 - MLB

Washington Nationals
3 :  11
Minnesota Twins

Jul 27, 2025 - MLB

Minnesota Twins
2 :  7
Washington Nationals

Jul 26, 2025 - MLB

Minnesota Twins
3 :  9
Washington Nationals

Jul 25, 2025 - MLB

Minnesota Twins
1 :  0
Washington Nationals

Washington Nationals - Minnesota Twins Key Points

  1. The all-time series between the Nationals and Twins is tied at 14-14.
  2. Washington is 20-15 ATS (run line) and Minnesota is 18-18 ATS (run line).
  3. The OVER is 22-12-2 for Washington and 20-13-3 for Minnesota.
  4. Betting Public: 90% of spread tickets and 97% of the handle are on the Twins.

Our Washington Nationals vs Minnesota Twins Prediction

I tend to hesitate when it comes to betting on the run line with baseball, because the nature of the game allows for any team to be competitive with another on any given day. Some teams are more or less likely to be competitive than others, but it is not unheard of to see a cellar dweller beat a division leader. However, in this case, I am comfortable going with the Twins run line because Mike Mikolas has been terrible this season. As long as Bailey Ober doesn’t have a terrible day, the Twins should cover this run line.

Our Minnesota vs. Washington Pick: Twins -1.5

Prediction:

 

Twins -1.5

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Washington Nationals vs Minnesota Twins Picks