St. Louis Cardinals vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

St. Louis Cardinals
3/29/25 14:15
Minnesota Twins

Prediction:

 

Over 7.5 runs.

-112
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 by Stephen Abiola | in MLB Picks

St. Louis Cardinals and Minnesota Twins are embroiled in a thrilling three-game series at Busch Stadium. The Cardinals come into this matchup hoping to find some success after a couple of disappointing campaigns by their own standards. They finished 2023 with a 71-91 record before slightly improving in 2024 to post an 83-79 record. The Cardinals have also missed the playoffs for two straight seasons, the first time since the 2016-2018 campaigns. They are under pressure to improve this season.

Likewise, Minnesota Twins experienced a frustrating 2025 MLB campaign, finishing the regular season with an 82-80 record. They have missed the postseason campaign thrice in the previous four seasons, a record they'll be eager to rectify in 2025. Minnesota Twins have been busy during the offseason, bringing in outfielder Harrison Bader and first baseman Ty France to strengthen the team. A playoff return could be on the horizon if they manage to stay healthy.

St. Louis Cardinals vs Minnesota Twins Form

Table

Teams Pts P W L
20 St. Louis Cardinals
0.481 162 78 84
27 Minnesota Twins
0.432 162 70 92

St. Louis Cardinals and Minnesota Twins Latest Matches

St. Louis Cardinals
St. Louis Cardinals Latest matches
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Mar 27, 2025 - MLB

St. Louis Cardinals
5 :  3
Minnesota Twins

Sep 19, 2024 - MLB

St. Louis Cardinals
2 :  3
Pittsburgh Pirates

Sep 18, 2024 - MLB

St. Louis Cardinals
10 :  5
Pittsburgh Pirates

Sep 17, 2024 - MLB

St. Louis Cardinals
3 :  1
Pittsburgh Pirates

Sep 13, 2024 - MLB

Toronto Blue Jays
4 :  3
St. Louis Cardinals

Sep 8, 2024 - MLB

St. Louis Cardinals
4 :  10
Seattle Mariners
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Mar 27, 2025 - MLB

St. Louis Cardinals
5 :  3
Minnesota Twins

Sep 19, 2024 - MLB

St. Louis Cardinals
2 :  3
Pittsburgh Pirates

Sep 18, 2024 - MLB

St. Louis Cardinals
10 :  5
Pittsburgh Pirates

Sep 17, 2024 - MLB

St. Louis Cardinals
3 :  1
Pittsburgh Pirates

Sep 8, 2024 - MLB

St. Louis Cardinals
4 :  10
Seattle Mariners

Aug 29, 2024 - MLB

St. Louis Cardinals
4 :  1
San Diego Padres
L L L L L L
Victories

0/6 (0%)

Defeats

6/6 (100%)

Sep 13, 2024 - MLB

Toronto Blue Jays
4 :  3
St. Louis Cardinals

Aug 13, 2024 - MLB

Cincinnati Reds
4 :  1
St. Louis Cardinals

Aug 10, 2024 - MLB

Kansas City Royals
8 :  3
St. Louis Cardinals

Aug 2, 2024 - MLB

Chicago Cubs
6 :  3
St. Louis Cardinals

Aug 1, 2024 - MLB

Chicago Cubs
5 :  4
St. Louis Cardinals

Jul 24, 2024 - MLB

Pittsburgh Pirates
5 :  0
St. Louis Cardinals
Minnesota Twins
Minnesota Twins Latest matches
L W L L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Mar 27, 2025 - MLB

St. Louis Cardinals
5 :  3
Minnesota Twins

Sep 29, 2024 - MLB

Minnesota Twins
2 :  6
Baltimore Orioles

Sep 22, 2024 - MLB

Boston Red Sox
8 :  1
Minnesota Twins

Sep 19, 2024 - MLB

Cleveland Guardians
3 :  2
Minnesota Twins

Sep 17, 2024 - MLB

Cleveland Guardians
1 :  4
Minnesota Twins

Sep 16, 2024 - MLB

Cleveland Guardians
4 :  3
Minnesota Twins
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 29, 2024 - MLB

Minnesota Twins
2 :  6
Baltimore Orioles

Sep 15, 2024 - MLB

Minnesota Twins
9 :  2
Cincinnati Reds

Sep 1, 2024 - MLB

Minnesota Twins
4 :  3
Toronto Blue Jays

Aug 28, 2024 - MLB

Minnesota Twins
1 :  5
Atlanta Braves

Aug 14, 2024 - MLB

Minnesota Twins
1 :  4
Kansas City Royals

Aug 13, 2024 - MLB

Minnesota Twins
13 :  3
Kansas City Royals
L L W L L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Mar 27, 2025 - MLB

St. Louis Cardinals
5 :  3
Minnesota Twins

Sep 22, 2024 - MLB

Boston Red Sox
8 :  1
Minnesota Twins

Sep 19, 2024 - MLB

Cleveland Guardians
3 :  2
Minnesota Twins

Sep 17, 2024 - MLB

Cleveland Guardians
1 :  4
Minnesota Twins

Sep 16, 2024 - MLB

Cleveland Guardians
4 :  3
Minnesota Twins

Sep 8, 2024 - MLB

Kansas City Royals
2 :  0
Minnesota Twins

St. Louis Cardinals against Minnesota Twins : Head to Head (H2H)

St. Louis Cardinals

50 %

Minnesota Twins

50 %

Mar 27, 2025 - MLB

St. Louis Cardinals
5 :  3
Minnesota Twins

Aug 3, 2023 - MLB

St. Louis Cardinals
3 :  5
Minnesota Twins

St. Louis Cardinals - Minnesota Twins Key Points

  1. The Twins had an average of 4.4 runs away from home last season.
  2. The Cardinals had an average of 4.1 runs at home last season.
  3. The total runs went over in the last five Minnesota games against NL teams.
  4. Minnesota Twins won against the run line in three of their previous six matches.

Our St. Louis Cardinals vs Minnesota Twins Prediction

We're going to take the Twins in this matchup. Not only are they the better team right now, but they also have a lot to prove this season. Their starting pitcher, Pablo Lopez, should give them an edge in most matches this season, boasting a 15-10 record with an ERA of 4.08. The Cardinals, meanwhile, could struggle after the departure of Paul Goldschmidt. This could see them miss the postseason, although they'll be fired up to prove their doubters wrong. They'll also aim to surprise everyone with an NL Central Title. We expect a very tight contest here. Our prediction for St. Louis Cardinals vs Minnesota Twins: Over 7.5 runs.

Prediction:

 

Over 7.5 runs.

-112
$200 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

St. Louis Cardinals vs Minnesota Twins Picks