St. Louis Cardinals vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

St. Louis Cardinals
3/27/25 16:15
Minnesota Twins

Prediction:

 

Twins -1.5 Runs

 

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 by Lou Aguila | in MLB Picks

The Minnesota Twins and the St. Louis Cardinals look to start their season on a strong note, kicking off their season-opening series at Busch Stadium on Thursday.

The Twins have won their last three games of Spring Training, flexing their improved offense against the Boston Red Sox 9-3, the Pittsburgh Pirates 5-1, and the Colorado Rockies 5-3. Pablo Lopez will step onto the mound as the opening-day starter for Minnesota, getting the nod after posting 15 wins with a 4.08 ERA last season.

The Cardinals have gone 3-2 in their last five games of Spring Training. They dropped their last exhibition game against the Washington Nationals 1-2 after Jack Sinclair allowed zero runs in 5.5 pitched innings. 13-9 with a 3.84 ERA last season, Sonny Gray will start for St. Louis on opening day.

St. Louis Cardinals vs Minnesota Twins Form

Table

Teams Pts P W L
20 St. Louis Cardinals
0.481 162 78 84
27 Minnesota Twins
0.432 162 70 92

St. Louis Cardinals and Minnesota Twins Latest Matches

St. Louis Cardinals
St. Louis Cardinals Latest matches
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 19, 2024 - MLB

St. Louis Cardinals
2 :  3
Pittsburgh Pirates

Sep 18, 2024 - MLB

St. Louis Cardinals
10 :  5
Pittsburgh Pirates

Sep 17, 2024 - MLB

St. Louis Cardinals
3 :  1
Pittsburgh Pirates

Sep 13, 2024 - MLB

Toronto Blue Jays
4 :  3
St. Louis Cardinals

Sep 8, 2024 - MLB

St. Louis Cardinals
4 :  10
Seattle Mariners

Aug 29, 2024 - MLB

St. Louis Cardinals
4 :  1
San Diego Padres
W W L W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 19, 2024 - MLB

St. Louis Cardinals
2 :  3
Pittsburgh Pirates

Sep 18, 2024 - MLB

St. Louis Cardinals
10 :  5
Pittsburgh Pirates

Sep 17, 2024 - MLB

St. Louis Cardinals
3 :  1
Pittsburgh Pirates

Sep 8, 2024 - MLB

St. Louis Cardinals
4 :  10
Seattle Mariners

Aug 29, 2024 - MLB

St. Louis Cardinals
4 :  1
San Diego Padres

Aug 28, 2024 - MLB

St. Louis Cardinals
4 :  3
San Diego Padres
L L L L L L
Victories

0/6 (0%)

Defeats

6/6 (100%)

Sep 13, 2024 - MLB

Toronto Blue Jays
4 :  3
St. Louis Cardinals

Aug 13, 2024 - MLB

Cincinnati Reds
4 :  1
St. Louis Cardinals

Aug 10, 2024 - MLB

Kansas City Royals
8 :  3
St. Louis Cardinals

Aug 2, 2024 - MLB

Chicago Cubs
6 :  3
St. Louis Cardinals

Aug 1, 2024 - MLB

Chicago Cubs
5 :  4
St. Louis Cardinals

Jul 24, 2024 - MLB

Pittsburgh Pirates
5 :  0
St. Louis Cardinals
Minnesota Twins
Minnesota Twins Latest matches
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 29, 2024 - MLB

Minnesota Twins
2 :  6
Baltimore Orioles

Sep 22, 2024 - MLB

Boston Red Sox
8 :  1
Minnesota Twins

Sep 19, 2024 - MLB

Cleveland Guardians
3 :  2
Minnesota Twins

Sep 17, 2024 - MLB

Cleveland Guardians
1 :  4
Minnesota Twins

Sep 16, 2024 - MLB

Cleveland Guardians
4 :  3
Minnesota Twins

Sep 15, 2024 - MLB

Minnesota Twins
9 :  2
Cincinnati Reds
W L L W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 29, 2024 - MLB

Minnesota Twins
2 :  6
Baltimore Orioles

Sep 15, 2024 - MLB

Minnesota Twins
9 :  2
Cincinnati Reds

Sep 1, 2024 - MLB

Minnesota Twins
4 :  3
Toronto Blue Jays

Aug 28, 2024 - MLB

Minnesota Twins
1 :  5
Atlanta Braves

Aug 14, 2024 - MLB

Minnesota Twins
1 :  4
Kansas City Royals

Aug 13, 2024 - MLB

Minnesota Twins
13 :  3
Kansas City Royals
L L L W L L
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 22, 2024 - MLB

Boston Red Sox
8 :  1
Minnesota Twins

Sep 19, 2024 - MLB

Cleveland Guardians
3 :  2
Minnesota Twins

Sep 17, 2024 - MLB

Cleveland Guardians
1 :  4
Minnesota Twins

Sep 16, 2024 - MLB

Cleveland Guardians
4 :  3
Minnesota Twins

Sep 8, 2024 - MLB

Kansas City Royals
2 :  0
Minnesota Twins

Sep 6, 2024 - MLB

Kansas City Royals
5 :  0
Minnesota Twins

St. Louis Cardinals against Minnesota Twins : Head to Head (H2H)

St. Louis Cardinals

0 %

Minnesota Twins

100 %

Aug 3, 2023 - MLB

St. Louis Cardinals
3 :  5
Minnesota Twins

St. Louis Cardinals - Minnesota Twins Key Points

  1. St. Louis are 2-5 SU in their last 7 games against an opponent in the American League.
  2. Minnesota are 1-7 SU in their last 8 games.
  3. Minnesota are 2-8 SU in their last 10 games on the road.
  4. St. Louis are 6-2 SU in their last 8 games.

Our St. Louis Cardinals vs Minnesota Twins Prediction

Minnesota Twins’ decision to start Pablo Lopez on opening days put them in a strong position to bag a straight-up and ATS win on Day 1 of the MLB 2025. Lopez has performed scintillating in his last two faceoffs with the Cardinals, throwing one earned run with 5 Ks on August 1 and a shutout with 9 strikeouts in a 6-0 win on August 24. Meanwhile, Cardinals starter Sonny Gray has lost two of his last three starts vs. Twins, including his previous duel with Lopez where he allowed five earned runs over six innings. Minnesota has scored 19 runs in their previous three games; St Louis has totaled 11 runs in their last three. Our betting prediction for Minnesota Twins vs. St. Louis Cardinals: Twins -1.5 runs.

Prediction:

 

Twins -1.5 Runs

 

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

St. Louis Cardinals vs Minnesota Twins Picks