Philadelphia Phillies vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

Philadelphia Phillies
9/26/25 18:45
Minnesota Twins

Prediction:

 

The Twins will win

+134
$350 offered for betting!

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 by Lou Aguila | in MLB Picks

The Philadelphia Phillies are set to kick off their final regular-season series against the Minnesota Twins on Friday at Citizens Bank Park.

The Phillies, the NL East champions, are -158 moneyline favorites ahead of the series-opener against the Twins, a team they have lost to 4 of their last five games.

Current Form:

The Phillies won the final two games of their series against the Miami Marlins, enhancing their regular-season record to 94-65. Over the last five games, Philadelphia has maintained a solid 3.20 ERA and averaged a modest 4.4 runs per game on a .256 batting average. Philadelphia has also posted more than two home runs per game (2.2 HR per game) over this five-game stretch.

The Twins are trying to close out their season on a high note, having won three of their last four games. After blanking the Texas Rangers 4-0 in Thursday’s series finale, Minnesota has lowered its ERA over the previous five games to 3.07 and WHIP to 0.97. Unfortunately, the Twins have still recorded mediocre offensive numbers in this stretch, averaging 3.3 runs per game on a .228 BA.

Philadelphia Phillies vs Minnesota Twins Form

Table

Teams Pts P W L
2 Philadelphia Phillies
0.593 162 96 66
27 Minnesota Twins
0.432 162 70 92

Philadelphia Phillies and Minnesota Twins Latest Matches

Philadelphia Phillies
Philadelphia Phillies Latest matches
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 25, 2025 - MLB

Philadelphia Phillies
1 :  0
Miami Marlins

Sep 24, 2025 - MLB

Philadelphia Phillies
11 :  1
Miami Marlins

Sep 23, 2025 - MLB

Philadelphia Phillies
5 :  6
Miami Marlins

Sep 21, 2025 - MLB

Arizona Diamondbacks
9 :  2
Philadelphia Phillies

Sep 20, 2025 - MLB

Arizona Diamondbacks
4 :  3
Philadelphia Phillies

Sep 19, 2025 - MLB

Arizona Diamondbacks
2 :  8
Philadelphia Phillies
W W L L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 25, 2025 - MLB

Philadelphia Phillies
1 :  0
Miami Marlins

Sep 24, 2025 - MLB

Philadelphia Phillies
11 :  1
Miami Marlins

Sep 23, 2025 - MLB

Philadelphia Phillies
5 :  6
Miami Marlins

Sep 14, 2025 - MLB

Philadelphia Phillies
3 :  10
Kansas City Royals

Sep 13, 2025 - MLB

Philadelphia Phillies
8 :  6
Kansas City Royals

Sep 12, 2025 - MLB

Philadelphia Phillies
8 :  2
Kansas City Royals
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 21, 2025 - MLB

Arizona Diamondbacks
9 :  2
Philadelphia Phillies

Sep 20, 2025 - MLB

Arizona Diamondbacks
4 :  3
Philadelphia Phillies

Sep 19, 2025 - MLB

Arizona Diamondbacks
2 :  8
Philadelphia Phillies

Sep 17, 2025 - MLB

Los Angeles Dodgers
5 :  0
Philadelphia Phillies

Sep 16, 2025 - MLB

Los Angeles Dodgers
6 :  9
Philadelphia Phillies

Sep 15, 2025 - MLB

Los Angeles Dodgers
5 :  6
Philadelphia Phillies
Minnesota Twins
Minnesota Twins Latest matches
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 25, 2025 - MLB

Texas Rangers
0 :  4
Minnesota Twins

Sep 24, 2025 - MLB

Texas Rangers
4 :  2
Minnesota Twins

Sep 23, 2025 - MLB

Texas Rangers
1 :  4
Minnesota Twins

Sep 21, 2025 - MLB

Minnesota Twins
6 :  2
Cleveland Guardians

Sep 20, 2025 - MLB

Minnesota Twins
0 :  8
Cleveland Guardians

Sep 20, 2025 - MLB

Minnesota Twins
0 :  6
Cleveland Guardians
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Sep 21, 2025 - MLB

Minnesota Twins
6 :  2
Cleveland Guardians

Sep 20, 2025 - MLB

Minnesota Twins
0 :  8
Cleveland Guardians

Sep 20, 2025 - MLB

Minnesota Twins
0 :  6
Cleveland Guardians

Sep 19, 2025 - MLB

Minnesota Twins
2 :  6
Cleveland Guardians

Sep 17, 2025 - MLB

Minnesota Twins
5 :  10
New York Yankees

Sep 16, 2025 - MLB

Minnesota Twins
9 :  10
New York Yankees
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 25, 2025 - MLB

Texas Rangers
0 :  4
Minnesota Twins

Sep 24, 2025 - MLB

Texas Rangers
4 :  2
Minnesota Twins

Sep 23, 2025 - MLB

Texas Rangers
1 :  4
Minnesota Twins

Sep 10, 2025 - MLB

Los Angeles Angels
4 :  3
Minnesota Twins

Sep 9, 2025 - MLB

Los Angeles Angels
12 :  2
Minnesota Twins

Sep 8, 2025 - MLB

Los Angeles Angels
3 :  12
Minnesota Twins

Philadelphia Phillies against Minnesota Twins : Head to Head (H2H)

Philadelphia Phillies

40 %

Minnesota Twins

60 %

Jul 24, 2024 - MLB

Minnesota Twins
5 :  4
Philadelphia Phillies

Jul 23, 2024 - MLB

Minnesota Twins
0 :  3
Philadelphia Phillies

Jul 22, 2024 - MLB

Minnesota Twins
7 :  2
Philadelphia Phillies

Feb 27, 2024 - MLB Spring Training

Minnesota Twins
3 :  3
Philadelphia Phillies

Aug 12, 2023 - MLB

Philadelphia Phillies
1 :  8
Minnesota Twins

Philadelphia Phillies - Minnesota Twins Key Points

  1. Minnesota is 5-10 SU in its last 15 games.
  2. Minnesota is 4-1 SU in its last 5 games against Philadelphia.
  3. Philadelphia is 14-6 SU in its last 20 games.
  4. Philadelphia is 4-2 SU in its last 6 games against an opponent in the American League Central Division

Our Philadelphia Phillies vs Minnesota Twins Prediction

Expect the Phillies to shut down their big bats like Bryce Harper, Trea Turner, and Kyle Schwarber for this series with the NL East title already in the bag. This could only mean Minnesota’s pitching staff will face Philadelphia’s batting lineup without the main engines of their offense.

Minnesota, 4-1 in their last five meetings against the Phillies, will start Joe Ryan (6.65 ERA in his last 5 starts). Ryan has lost his previous three starts and four of his last five, but the Twins are optimistic he will deliver a better showing against the Phillies’ shorthanded offense. Minnesota could also take advantage of Aaron Nola’s recent shaky form. Nola (6.35 ERA in his last five starts) has surrendered 10 runs over his previous two starts.

Again, the Phillies can afford to lose all three games in this series against Minnesota and still end up with the No.2 seed in the NL East.

Fearless Forecast: Twins 5, Phillies 2

Our betting prediction for the Minnesota Twins vs. the Philadelphia Phillies: Twins will win

Prediction:

 

The Twins will win

+134
$350 offered for betting!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Philadelphia Phillies vs Minnesota Twins Picks