Minnesota Twins vs Cleveland Guardians Prediction & Picks - MLB

USA - MLB

Minnesota Twins
4/29/25 18:10
Cleveland Guardians

Prediction:

 

Twins will win

+115
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 by Lou Aguila in MLB Picks

The Minnesota Twins will try to push their winning streak to five games when they play the Cleveland Guardians in Game 2 of their series on Tuesday at Progressive Field.

The Twins have won four in a row, including an 11-1 win over the Guardians in their series opener on Monday. Minnesota’s terrific form in their winning streak has elevated both their batting and pitching numbers. Still fourth in the American League Central with a 13-16 record, the Twins are batting .234 with 117 runs and pitching a 3.55 ERA this season.

Meanwhile, the Guardians have conceded the top position in the AL Central after losing four of their last five games, including their last three assignments. Cleveland has conceded too many runs in their last five games, pitching a 7.80 ERA and .406 OBP.

Minnesota Twins vs Cleveland Guardians Form

Table

Teams % P W L
14
Cleveland Guardians
Cleveland Guardians
0.513 76 39 37
21
Minnesota Twins
Minnesota Twins
0.481 77 37 40

Minnesota Twins and Cleveland Guardians Latest Matches

Minnesota Twins
Minnesota Twins Latest matches
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins

Apr 24, 2025 - MLB

Chicago White Sox
3 :  0
Minnesota Twins

Apr 23, 2025 - MLB

Chicago White Sox
3 :  6
Minnesota Twins
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 27, 2025 - MLB

Los Angeles Angels
0 :  5
Minnesota Twins

Apr 26, 2025 - MLB

Los Angeles Angels
1 :  5
Minnesota Twins

Apr 25, 2025 - MLB

Los Angeles Angels
4 :  11
Minnesota Twins

Apr 24, 2025 - MLB

Chicago White Sox
3 :  0
Minnesota Twins

Apr 23, 2025 - MLB

Chicago White Sox
3 :  6
Minnesota Twins

Apr 22, 2025 - MLB

Chicago White Sox
2 :  4
Minnesota Twins
W L L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 20, 2025 - MLB

Minnesota Twins
2 :  6
Atlanta Braves

Apr 19, 2025 - MLB

Minnesota Twins
3 :  4
Atlanta Braves

Apr 18, 2025 - MLB

Minnesota Twins
4 :  6
Atlanta Braves

Apr 10, 2025 - MLB

Minnesota Twins
2 :  3
Kansas City Royals

Apr 9, 2025 - MLB

Minnesota Twins
4 :  0
Kansas City Royals
Cleveland Guardians
Cleveland Guardians Latest matches
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians

Apr 22, 2025 - MLB

New York Yankees
2 :  3
Cleveland Guardians
W L L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Apr 27, 2025 - MLB

Boston Red Sox
13 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
7 :  3
Cleveland Guardians

Apr 26, 2025 - MLB

Boston Red Sox
4 :  5
Cleveland Guardians

Apr 23, 2025 - MLB

New York Yankees
5 :  1
Cleveland Guardians

Apr 22, 2025 - MLB

New York Yankees
2 :  3
Cleveland Guardians
W L L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Apr 20, 2025 - MLB

Cleveland Guardians
5 :  4
Pittsburgh Pirates

Apr 19, 2025 - MLB

Cleveland Guardians
3 :  0
Pittsburgh Pirates

Apr 18, 2025 - MLB

Cleveland Guardians
10 :  7
Pittsburgh Pirates

Apr 17, 2025 - MLB

Cleveland Guardians
2 :  6
Baltimore Orioles

Apr 16, 2025 - MLB

Cleveland Guardians
1 :  9
Baltimore Orioles

Apr 15, 2025 - MLB

Cleveland Guardians
6 :  3
Baltimore Orioles

Minnesota Twins against Cleveland Guardians : Head to Head (H2H)

Minnesota Twins

33 %

Cleveland Guardians

67 %

Apr 28, 2025 - MLB

Minnesota Twins
11 :  1
Cleveland Guardians

Sep 19, 2024 - MLB

Minnesota Twins
2 :  3
Cleveland Guardians

Sep 18, 2024 - MLB

Minnesota Twins
4 :  5
Cleveland Guardians

Sep 17, 2024 - MLB

Minnesota Twins
4 :  1
Cleveland Guardians

Sep 16, 2024 - MLB

Minnesota Twins
3 :  4
Cleveland Guardians

Aug 11, 2024 - MLB

Cleveland Guardians
5 :  3
Minnesota Twins

Minnesota Twins - Cleveland Guardians Key Points

  1. Minnesota is 6-1 SU in its last 7 games.
  2. Minnesota is 4-12 SU in its last 16 games on the road.
  3. Cleveland is 1-4 SU in its last 5 games.
  4. Cleveland is 7-2 SU in its last 9 games when playing at home against Minnesota.

Our Minnesota Twins vs Cleveland Guardians Prediction

The Twins are just 4-11 SU in its last 15 games against Cleveland, but I still think they will win convincingly on Tuesday behind another explosive night by their batting corps. Minnesota enters Game 2 against the Guardians, averaging 7.2 runs per game on a .323 batting average. The Guardians’ pitching has been dreadful over their last five games, especially the starters, who have posted a 12.05 ERA in this stretch. Twins starter Chris Paddack carries a 6.45 ERA but has delivered solid numbers in his last three starts, including a pair of games with one earned run allowed. Guardians hurler Tanner Bibee has been erratic with a 5.19 ERA. Our betting prediction for the Cleveland Guardians vs. Minnesota Twins: The Guardians will win.

Prediction:

 

Twins will win

+115
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Minnesota Twins vs Cleveland Guardians Picks