Chicago White Sox vs Minnesota Twins Prediction & Picks - MLB

Prediction published on 9/4/26, 12:47 PM  by Lou Aguila | Modified on 9/4/26 at 12:49 PM in MLB Picks

The Minnesota Twins will bank on their red-hot offense (7.8 runs over the last five games) and Zebby Matthews (2.90 ERA over his last 5 starts) to score a comfortable win over the Chicago White Sox in Game 1.

The Twins are a tempting option at +158 to cover -1.5 runs in this game.

Current Form:

The Minnesota Twins are 3-2 in their last five games, having seen their three-game winning streak snapped by the Detroit Tigers, 6-1, in the extra innings of their series finale. Over the last five games, the Twins have averaged 7.8 runs per game on a .260 clip.

The Chicago White Sox have lost 4 of their last 5 games, dropping to 73-67 on the season. The White Sox still hold the top position in the AL Central, though their lead over the 70-70 Cleveland Guardians has dwindled to three games. Aside from their 4.17 ERA, hitting has been the major problem lately for Chicago, which averages 2.2 runs on a .179 BA.

Starting Pitchers: White Sox RHP Eric Fedde (7-8, 4.16 ERA) vs. Twins RHP Zebby Matthews (9-8, 4.58 ERA).

The Matchup: The White Sox are 6-4 against the Twins in their last 10 meetings, but Minnesota won their last encounter, 5-1, behind the pitching brilliance of Zebby Matthews.