Chicago White Sox vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

Chicago White Sox
5/28/26 14:10
Minnesota Twins

Prediction:

 

The White Sox -1.5 Runs

+150
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 by Lou Aguila | in MLB Picks

The Chicago White Sox (28-27) displayed their offensive prowess in their 15-2 win over the Twins. The White Sox hiked up their run production to 5.8 runs per game on a .267 batting average over their last five games.

The Minnesota Twins (27-29) seek to tie the series at 2-2 after losing 2 of the first 3 games of this see-saw series against their division rivals. Minnesota is averaging only 3.4 runs per game while posting a 5.40 ERA in the past 5 games.

Match Analysis:

The White Sox, who currently trade at -145 moneyline and +150 to cover -1.5 games, will send Dave Martin to the mound in the series finale.

Martin has made a strong case for a CY Young Award nomination after sporting a 7-1 record with a 2.04 ERA through 10 starts. The White Sox are 9-1 whenever Martin takes the mound.

Meanwhile, the Twins will counter with left-handed pitcher Kendry Rojas, who has helped Minnesota secure victory in his last four mound appearances. Rojas, who sports a 1.26 ERA this season, is set to make his second start this season.

Since two strong pitchers are slated to go head-to-head in the opening innings of this game, it seems that pitching is back to dominate again after a 17-run Game 2.

However, with the way the White Sox are batting as of late, not even Rojas can tame this high-powered offensive unit led by rookie sensation Munetaka Murakami.

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Chicago White Sox vs Minnesota Twins Form

Table

Teams Pts P W L
9 Chicago White Sox
0.526 95 50 45
16 Minnesota Twins
0.495 97 48 49

Chicago White Sox and Minnesota Twins Latest Matches

Chicago White Sox
Chicago White Sox Latest matches
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 27, 2026 - MLB

Chicago White Sox
15 :  2
Minnesota Twins

May 26, 2026 - MLB

Chicago White Sox
3 :  5
Minnesota Twins

May 25, 2026 - MLB

Chicago White Sox
3 :  1
Minnesota Twins

May 24, 2026 - MLB

San Francisco Giants
8 :  5
Chicago White Sox

May 23, 2026 - MLB

San Francisco Giants
10 :  3
Chicago White Sox

May 22, 2026 - MLB

San Francisco Giants
4 :  9
Chicago White Sox
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 27, 2026 - MLB

Chicago White Sox
15 :  2
Minnesota Twins

May 26, 2026 - MLB

Chicago White Sox
3 :  5
Minnesota Twins

May 25, 2026 - MLB

Chicago White Sox
3 :  1
Minnesota Twins

May 17, 2026 - MLB

Chicago White Sox
9 :  8
Chicago Cubs

May 16, 2026 - MLB

Chicago White Sox
8 :  3
Chicago Cubs

May 15, 2026 - MLB

Chicago White Sox
5 :  10
Chicago Cubs
L W L W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 24, 2026 - MLB

San Francisco Giants
8 :  5
Chicago White Sox

May 23, 2026 - MLB

San Francisco Giants
10 :  3
Chicago White Sox

May 22, 2026 - MLB

San Francisco Giants
4 :  9
Chicago White Sox

May 20, 2026 - MLB

Seattle Mariners
5 :  4
Chicago White Sox

May 19, 2026 - MLB

Seattle Mariners
1 :  2
Chicago White Sox

May 18, 2026 - MLB

Seattle Mariners
6 :  1
Chicago White Sox
Minnesota Twins
Minnesota Twins Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 27, 2026 - MLB

Chicago White Sox
15 :  2
Minnesota Twins

May 26, 2026 - MLB

Chicago White Sox
3 :  5
Minnesota Twins

May 25, 2026 - MLB

Chicago White Sox
3 :  1
Minnesota Twins

May 24, 2026 - MLB

Boston Red Sox
5 :  6
Minnesota Twins

May 23, 2026 - MLB

Boston Red Sox
2 :  4
Minnesota Twins

May 22, 2026 - MLB

Boston Red Sox
6 :  8
Minnesota Twins
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 20, 2026 - MLB

Minnesota Twins
4 :  1
Houston Astros

May 19, 2026 - MLB

Minnesota Twins
1 :  2
Houston Astros

May 18, 2026 - MLB

Minnesota Twins
6 :  3
Houston Astros

May 17, 2026 - MLB

Minnesota Twins
5 :  4
Milwaukee Brewers

May 16, 2026 - MLB

Minnesota Twins
1 :  2
Milwaukee Brewers

May 15, 2026 - MLB

Minnesota Twins
2 :  3
Milwaukee Brewers
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 27, 2026 - MLB

Chicago White Sox
15 :  2
Minnesota Twins

May 26, 2026 - MLB

Chicago White Sox
3 :  5
Minnesota Twins

May 25, 2026 - MLB

Chicago White Sox
3 :  1
Minnesota Twins

May 24, 2026 - MLB

Boston Red Sox
5 :  6
Minnesota Twins

May 23, 2026 - MLB

Boston Red Sox
2 :  4
Minnesota Twins

May 22, 2026 - MLB

Boston Red Sox
6 :  8
Minnesota Twins

Chicago White Sox against Minnesota Twins : Head to Head (H2H)

Chicago White Sox

83 %

Minnesota Twins

17 %

May 27, 2026 - MLB

Chicago White Sox
15 :  2
Minnesota Twins

May 26, 2026 - MLB

Chicago White Sox
3 :  5
Minnesota Twins

May 25, 2026 - MLB

Chicago White Sox
3 :  1
Minnesota Twins

Sep 4, 2025 - MLB

Minnesota Twins
8 :  11
Chicago White Sox

Sep 3, 2025 - MLB

Minnesota Twins
3 :  4
Chicago White Sox

Sep 2, 2025 - MLB

Minnesota Twins
3 :  12
Chicago White Sox
Chicago White Sox vs Minnesota Twins Picks

Chicago White Sox - Minnesota Twins Key Points

  1. Minnesota is 1-8 SU in its last 9 games against Chicago White Sox.
  2. Minnesota is 1-4 SU in its last 5 games when playing on the road against Chicago White Sox.
  3. Chicago White Sox is 4-1 SU in its last 5 games when playing at home against Minnesota.
  4. Chicago White Sox is 8-3 SU in its last 11 games against an opponent in the American League.
Up to $250 to bet on Chicago White Sox - Minnesota Twins! 

Limited Offer. Currently at Caesars Sportsbook

Our Chicago White Sox vs Minnesota Twins Prediction

Back the White Sox to cover -1.5 runs.

Chicago has won 8 of their last 9 meetings with Minnesota. In their last 10 faceoffs, the White Sox have averaged 7.6 runs per game and limited the Twins to 3.9 runs per contest.

Dave Martin will only make it harder for the Twins to compete with the White Sox, as the pitcher is absolutely on a tear this season.

Our betting prediction for the Minnesota Twins vs. the Chicago White Sox: The White Sox -1.5 Runs

Prediction:

 

The White Sox -1.5 Runs

+150
$250 offered for betting!

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