Boston Red Sox vs Minnesota Twins Prediction & Picks - MLB

USA - MLB

Boston Red Sox
5/22/26 19:10
Minnesota Twins

Prediction:

 

Boston Red Sox win the match

-156
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 by Carlos Zabala | in MLB Picks

The Red Sox, amid a 22-27 record, have managed to emerge victorious from series against Central Division rivals; they previously defeated the Tigers in Detroit, swept the Royals at Kauffman Stadium, and, starting Friday, will host the Twins in a May that is beginning to look promising for this Boston team, now without Cora at the helm.

No news is more crucial for the Red Sox right now than the resurgence of Jaren Duran's bat after a forgettable start to the season that still has him batting .195. The Red Sox's leadoff hitter is beginning to turn his season around: going 7-for-19, he has hit in his last five games, homering in the final two of the series against Kansas City, including a powerful swing to the opposite field.

That's an indication that other Red Sox hitters are contributing to Contreras's success. Almost always batting cleanup, he's silencing critics who advise against bringing him to Boston. The Venezuelan went 3-for-4 on Wednesday, and his batting average has been rising; only Rafaela is hitting for a better average on the Red Sox.

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Boston Red Sox vs Minnesota Twins Form

Table

Teams Pts P W L
7 Boston Red Sox
0.542 118 64 54
16 Minnesota Twins
0.492 120 59 61

Boston Red Sox and Minnesota Twins Latest Matches

Boston Red Sox
Boston Red Sox Latest matches
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 20, 2026 - MLB

Kansas City Royals
3 :  4
Boston Red Sox

May 19, 2026 - MLB

Kansas City Royals
1 :  7
Boston Red Sox

May 18, 2026 - MLB

Kansas City Royals
1 :  3
Boston Red Sox

May 17, 2026 - MLB

Atlanta Braves
8 :  1
Boston Red Sox

May 16, 2026 - MLB

Atlanta Braves
2 :  3
Boston Red Sox

May 15, 2026 - MLB

Atlanta Braves
3 :  2
Boston Red Sox
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 14, 2026 - MLB

Boston Red Sox
1 :  3
Philadelphia Phillies

May 13, 2026 - MLB

Boston Red Sox
3 :  1
Philadelphia Phillies

May 12, 2026 - MLB

Boston Red Sox
1 :  2
Philadelphia Phillies

May 10, 2026 - MLB

Boston Red Sox
1 :  4
Tampa Bay Rays

May 8, 2026 - MLB

Boston Red Sox
2 :  0
Tampa Bay Rays

May 7, 2026 - MLB

Boston Red Sox
4 :  8
Tampa Bay Rays
L W L W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 20, 2026 - MLB

Kansas City Royals
3 :  4
Boston Red Sox

May 19, 2026 - MLB

Kansas City Royals
1 :  7
Boston Red Sox

May 18, 2026 - MLB

Kansas City Royals
1 :  3
Boston Red Sox

May 17, 2026 - MLB

Atlanta Braves
8 :  1
Boston Red Sox

May 16, 2026 - MLB

Atlanta Braves
2 :  3
Boston Red Sox

May 15, 2026 - MLB

Atlanta Braves
3 :  2
Boston Red Sox
Minnesota Twins
Minnesota Twins Latest matches
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 20, 2026 - MLB

Minnesota Twins
4 :  1
Houston Astros

May 19, 2026 - MLB

Minnesota Twins
1 :  2
Houston Astros

May 18, 2026 - MLB

Minnesota Twins
6 :  3
Houston Astros

May 17, 2026 - MLB

Minnesota Twins
5 :  4
Milwaukee Brewers

May 16, 2026 - MLB

Minnesota Twins
1 :  2
Milwaukee Brewers

May 15, 2026 - MLB

Minnesota Twins
2 :  3
Milwaukee Brewers
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 20, 2026 - MLB

Minnesota Twins
4 :  1
Houston Astros

May 19, 2026 - MLB

Minnesota Twins
1 :  2
Houston Astros

May 18, 2026 - MLB

Minnesota Twins
6 :  3
Houston Astros

May 17, 2026 - MLB

Minnesota Twins
5 :  4
Milwaukee Brewers

May 16, 2026 - MLB

Minnesota Twins
1 :  2
Milwaukee Brewers

May 15, 2026 - MLB

Minnesota Twins
2 :  3
Milwaukee Brewers
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 10, 2026 - MLB

Cleveland Guardians
4 :  5
Minnesota Twins

May 9, 2026 - MLB

Cleveland Guardians
1 :  2
Minnesota Twins

May 8, 2026 - MLB

Cleveland Guardians
6 :  4
Minnesota Twins

May 7, 2026 - MLB

Washington Nationals
7 :  5
Minnesota Twins

May 6, 2026 - MLB

Washington Nationals
15 :  2
Minnesota Twins

May 5, 2026 - MLB

Washington Nationals
3 :  11
Minnesota Twins

Boston Red Sox against Minnesota Twins : Head to Head (H2H)

Boston Red Sox

33 %

Minnesota Twins

67 %

Apr 15, 2026 - MLB

Minnesota Twins
5 :  9
Boston Red Sox

Apr 14, 2026 - MLB

Minnesota Twins
6 :  0
Boston Red Sox

Apr 13, 2026 - MLB

Minnesota Twins
13 :  6
Boston Red Sox

Mar 24, 2026 - MLB Spring Training

Minnesota Twins
15 :  6
Boston Red Sox

Mar 23, 2026 - MLB Spring Training

Boston Red Sox
6 :  9
Minnesota Twins

Mar 19, 2026 - MLB Spring Training

Boston Red Sox
4 :  2
Minnesota Twins
Boston Red Sox vs Minnesota Twins Picks

Boston Red Sox - Minnesota Twins Key Points

  1. The Red Sox won three straight games for the third time in 2026
  2. The Twins have an 8-13 record away from Minneapolis
  3. The Twins won the series against the Red Sox 2-1 at Target Field
  4. Boston's pitching staff has allowed the second-most home runs in MLB this season
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Our Boston Red Sox vs Minnesota Twins Prediction

With a record almost identical to the Red Sox's, the Twins took the series against the Astros 2-1, but at a high price. They've temporarily lost their best hitter, Ryan Jeffers, due to a hand injury. Manager Derek Shelton said he would need multiple players to compensate for his offensive production.

The Red Sox have the momentum. Tolle has the opportunity on the mound to lead Boston to its first four wins of the season. With his dynamic pitching, Tolle is already a fan favorite and is poised to become their ace in the near future. They desperately need a performance like the one on April 23rd when he struck out 11 Yankees.

Our prediction for Red Sox vs Twins is: Red Sox ML.

Prediction:

 

Boston Red Sox win the match

-156
$150 offered for betting!

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