Baltimore Orioles vs Minnesota Twins Prediction & Picks - MLB
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by Lou Aguila | in MLB Picks
The Baltimore Orioles open the new season carrying a tempting +149 price on the -1.5 run line against the visiting Minnesota Twins on Thursday.
Momentum: The Orioles have won four of their last five Spring Training games, including their last three. The Twins wrapped up their training with a 3-0 record, highlighted by two impressive wins over the Boston Red Sox (15-6 and 9-6).
The Matchup: It will be the season-opener for both teams. Right-handed pitcher Joe Ryan (13-10, 3.42 ERA in 2025) will start for the Twins, while lefty Trevor Rogers (9-3, 1.81 ERA in 2025) gets the starting nod from the Orioles.
The Betting Board: The Twins are the road underdogs at +119, but the home favorites, the Orioles, still offer a competitive price at -143. Baltimore at -1.5 runs is valued handsomely at +149.
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Baltimore Orioles vs Minnesota Twins Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
22
|
0.464 | 84 | 39 | 45 |
|
22
|
0.464 | 84 | 39 | 45 |
Baltimore Orioles and Minnesota Twins Latest Matches
4/6 (67%)
2/6 (33%)
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
5/6 (83%)
1/6 (17%)
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 11, 2026 - MLB Spring Training
Mar 8, 2026 - MLB Spring Training
Mar 7, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 23, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 18, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
3/6 (50%)
3/6 (50%)
Mar 24, 2026 - MLB Spring Training
Mar 23, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
4/6 (67%)
2/6 (33%)
Mar 24, 2026 - MLB Spring Training
Mar 22, 2026 - MLB Spring Training
Mar 20, 2026 - MLB Spring Training
Mar 16, 2026 - MLB Spring Training
Mar 14, 2026 - MLB Spring Training
Mar 12, 2026 - MLB Spring Training
1/6 (17%)
5/6 (83%)
Mar 23, 2026 - MLB Spring Training
Mar 21, 2026 - MLB Spring Training
Mar 19, 2026 - MLB Spring Training
Mar 17, 2026 - MLB Spring Training
Mar 15, 2026 - MLB Spring Training
Mar 13, 2026 - MLB Spring Training
Baltimore Orioles against Minnesota Twins : Head to Head (H2H)
33 %
67 %
Mar 7, 2026 - MLB Spring Training
Feb 24, 2026 - MLB Spring Training
May 14, 2025 - MLB
May 14, 2025 - MLB
May 8, 2025 - MLB
May 7, 2025 - MLB
Baltimore Orioles - Minnesota Twins Key Points
- Baltimore is 4-1 SU in its last 5 games against an opponent in the American League Central Division
- Minnesota is 6-12 SU in its last 18 games.
- The total has gone UNDER in 9 of Minnesota's last 9 games.
- The total has gone UNDER in 8 of Baltimore's last 11 games.
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Our Baltimore Orioles vs Minnesota Twins Prediction
Fearless Forecast: The Orioles top the Twins 4-2
Best Bet: Regardless of its risk, placing a wager on the Orioles at -1.5 runs is definitely worth a gamble because of its lucrative +149 price on DraftKings. The Twins’ offense looked deadly after scoring 31 runs over their last 3 spring training games. On the other hand, the Orioles gave up a single run to the Nationals in their last two preseason games.
Secondary Pick: Under 8 runs is the pick here. Birds’ Trevor Rogers is an excellent starter who can hold the Twins scoreless for several innings. The Orioles’ bullpen has also impressed in the final two games. Despite his 13-10 record in 2025, Twins Joe Ryan isn’t bad either, with a decent 3.42 ERA. The total has gone UNDER in 9 of Minnesota's last 9 games and 8 of Baltimore's last 11 games.
Our betting prediction for the Minnesota Twins vs. the Baltimore Orioles: The Orioles -1.5 Runs
All tips are fully researched and given in good faith, but profits cannot be guaranteed.