St. Louis Cardinals vs Milwaukee Brewers Prediction & Picks - MLB

USA - MLB

St. Louis Cardinals
5/5/26 19:45
Milwaukee Brewers

Prediction:

 

Over 8 Total Runs

-105
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 by Matt Lowrimore | in MLB Picks

A full 15-game MLB slate is scheduled for Tuesday, which will include a National League Central matchup between the St. Louis Cardinals and the Milwaukee Brewers. Let’s take a look at the match statistics and predictions for this game between the Cardinals and the Brewers.

After a hot start, Milwaukee has cooled off considerably. As a result of this, the Brewers are sitting in fourth place in a packed NL Central division. Starting Game 2 of this series for Milwaukee will be Brandon Sproat. He enters this game with a record of 0-2, but a poor 6.75 ERA. Sproat has particularly struggled on the road this season, which suggests he could have a rough time against a solid Cardinals’ offense. 

As for St. Louis, they have been an above-average team thus far and will be scheduled to start Andre Pallante, who is 3-2 on the season, with an ERA of 3.73. His struggles have mainly come at home, suggesting the Brewers could get to him early as well.

St. Louis Cardinals vs Milwaukee Brewers Form

Table

Teams Pts P W L
2 Milwaukee Brewers
0.625 80 50 30
11 St. Louis Cardinals
0.525 80 42 38

St. Louis Cardinals and Milwaukee Brewers Latest Matches

St. Louis Cardinals
St. Louis Cardinals Latest matches
W W W W L W
Victories

5/6 (83%)

Defeats

1/6 (17%)

May 4, 2026 - MLB

St. Louis Cardinals
6 :  3
Milwaukee Brewers

May 3, 2026 - MLB

St. Louis Cardinals
1 :  4
Los Angeles Dodgers

May 2, 2026 - MLB

St. Louis Cardinals
3 :  2
Los Angeles Dodgers

May 1, 2026 - MLB

St. Louis Cardinals
7 :  2
Los Angeles Dodgers

Apr 30, 2026 - MLB

Pittsburgh Pirates
5 :  10
St. Louis Cardinals

Apr 29, 2026 - MLB

Pittsburgh Pirates
4 :  5
St. Louis Cardinals
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 4, 2026 - MLB

St. Louis Cardinals
6 :  3
Milwaukee Brewers

May 3, 2026 - MLB

St. Louis Cardinals
1 :  4
Los Angeles Dodgers

May 2, 2026 - MLB

St. Louis Cardinals
3 :  2
Los Angeles Dodgers

May 1, 2026 - MLB

St. Louis Cardinals
7 :  2
Los Angeles Dodgers

Apr 26, 2026 - MLB

St. Louis Cardinals
2 :  3
Seattle Mariners

Apr 25, 2026 - MLB

St. Louis Cardinals
9 :  11
Seattle Mariners
W L W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Apr 30, 2026 - MLB

Pittsburgh Pirates
5 :  10
St. Louis Cardinals

Apr 29, 2026 - MLB

Pittsburgh Pirates
4 :  5
St. Louis Cardinals

Apr 28, 2026 - MLB

Pittsburgh Pirates
7 :  11
St. Louis Cardinals

Apr 27, 2026 - MLB

Pittsburgh Pirates
2 :  4
St. Louis Cardinals

Apr 22, 2026 - MLB

Miami Marlins
4 :  1
St. Louis Cardinals

Apr 21, 2026 - MLB

Miami Marlins
3 :  5
St. Louis Cardinals
Milwaukee Brewers
Milwaukee Brewers Latest matches
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 4, 2026 - MLB

St. Louis Cardinals
6 :  3
Milwaukee Brewers

May 3, 2026 - MLB

Washington Nationals
3 :  2
Milwaukee Brewers

May 2, 2026 - MLB

Washington Nationals
1 :  4
Milwaukee Brewers

May 1, 2026 - MLB

Washington Nationals
1 :  6
Milwaukee Brewers

Apr 30, 2026 - MLB

Milwaukee Brewers
13 :  1
Arizona Diamondbacks

Apr 29, 2026 - MLB

Milwaukee Brewers
2 :  6
Arizona Diamondbacks
L L W W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 30, 2026 - MLB

Milwaukee Brewers
13 :  1
Arizona Diamondbacks

Apr 29, 2026 - MLB

Milwaukee Brewers
2 :  6
Arizona Diamondbacks

Apr 28, 2026 - MLB

Milwaukee Brewers
13 :  2
Arizona Diamondbacks

Apr 26, 2026 - MLB

Milwaukee Brewers
5 :  0
Pittsburgh Pirates

Apr 25, 2026 - MLB

Milwaukee Brewers
3 :  6
Pittsburgh Pirates

Apr 24, 2026 - MLB

Milwaukee Brewers
0 :  6
Pittsburgh Pirates
L L W W L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

May 4, 2026 - MLB

St. Louis Cardinals
6 :  3
Milwaukee Brewers

May 3, 2026 - MLB

Washington Nationals
3 :  2
Milwaukee Brewers

May 2, 2026 - MLB

Washington Nationals
1 :  4
Milwaukee Brewers

May 1, 2026 - MLB

Washington Nationals
1 :  6
Milwaukee Brewers

Apr 23, 2026 - MLB

Detroit Tigers
5 :  4
Milwaukee Brewers

Apr 22, 2026 - MLB

Detroit Tigers
5 :  2
Milwaukee Brewers

St. Louis Cardinals against Milwaukee Brewers : Head to Head (H2H)

St. Louis Cardinals

67 %

Milwaukee Brewers

33 %

May 4, 2026 - MLB

St. Louis Cardinals
6 :  3
Milwaukee Brewers

Sep 21, 2025 - MLB

St. Louis Cardinals
5 :  1
Milwaukee Brewers

Sep 20, 2025 - MLB

St. Louis Cardinals
2 :  3
Milwaukee Brewers

Sep 19, 2025 - MLB

St. Louis Cardinals
7 :  1
Milwaukee Brewers

Sep 14, 2025 - MLB

Milwaukee Brewers
2 :  3
St. Louis Cardinals

Sep 13, 2025 - MLB

Milwaukee Brewers
9 :  8
St. Louis Cardinals

St. Louis Cardinals - Milwaukee Brewers Key Points

  1. Brandon Sproat has an ERA of 6.75 this season
  2. Brandon Sproat has an ERA of 7.00 on the road
  3. Andre Pallente has an ERA of 3.73 this season
  4. Andre Pallente has an ERA of 5.28 at home

Our St. Louis Cardinals vs Milwaukee Brewers Prediction

This game is about as evenly matched as it can be; therefore, we will simply be looking for runs to be scored. Going back to Sproat’s struggles on the road, he has made two away appearances (one start) this season, in which he has allowed seven earned runs over 8.0 innings.

Pallente, on the other hand, has made three home starts this season, where he has allowed 10 runs (nine earned) over 15.1 innings. Even though the Brewers’ offense has been struggling recently, with neither starting pitcher having shown consistency, our St. Louis Cardinals vs Milwaukee Brewers prediction is: Over 8 Total Runs.

Prediction:

 

Over 8 Total Runs

-105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

St. Louis Cardinals vs Milwaukee Brewers Picks