Chicago Cubs vs Milwaukee Brewers Prediction & Picks - MLB
USA - MLB
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Erik Gibbs | in MLB Picks
The Milwaukee Brewers hold a 2‑0 lead in their National League Division Series after dispatching the Chicago Cubs 7‑3 in Game 2. Milwaukee enjoyed a stellar 2025 regular season, compiling a 97‑65 record that topped the NL Central by five games. They forged that mark through balanced play: the Brewers ranked among league leaders in runs scored and team ERA, benefitting from strong defense and solid baserunning. Down the stretch they surged, winning nine of their last 12 games to secure home‑field advantage.
Chicago, meanwhile, finished the season 92‑70 and secured a wild‑card berth. The Cubs' regular season was defined by streaks of brilliance mixed with inconsistency; they posted a 50‑31 record at Wrigley Field but were only slightly above .500 on the road. In the postseason, the Cubs eked out a wild‑card series win but have struggled to match Milwaukee's scoring output in the NLDS.
The Brewers' offense has flexed its muscle, plating 14 runs across the first two games and capitalizing on two‑out opportunities. Chicago's pitching staff has been unable to escape jams, allowing timely hits that have turned close games into multi‑run deficits.
Limited Offer. Currently at FanDuel
Chicago Cubs vs Milwaukee Brewers Form
Chicago Cubs and Milwaukee Brewers Latest Matches
3/6 (50%)
3/6 (50%)
Oct 6, 2025 - MLB
Oct 4, 2025 - MLB
Oct 2, 2025 - MLB
Oct 1, 2025 - MLB
Sep 30, 2025 - MLB
Sep 28, 2025 - MLB
5/6 (83%)
1/6 (17%)
Oct 2, 2025 - MLB
Oct 1, 2025 - MLB
Sep 30, 2025 - MLB
Sep 28, 2025 - MLB
Sep 27, 2025 - MLB
Sep 26, 2025 - MLB
0/6 (0%)
6/6 (100%)
Oct 6, 2025 - MLB
Oct 4, 2025 - MLB
Sep 21, 2025 - MLB
Sep 20, 2025 - MLB
Sep 19, 2025 - MLB
Sep 18, 2025 - MLB
4/6 (67%)
2/6 (33%)
Oct 6, 2025 - MLB
Oct 4, 2025 - MLB
Sep 28, 2025 - MLB
Sep 27, 2025 - MLB
Sep 26, 2025 - MLB
Sep 24, 2025 - MLB
4/6 (67%)
2/6 (33%)
Oct 6, 2025 - MLB
Oct 4, 2025 - MLB
Sep 28, 2025 - MLB
Sep 27, 2025 - MLB
Sep 26, 2025 - MLB
Sep 18, 2025 - MLB
2/6 (33%)
4/6 (67%)
Sep 24, 2025 - MLB
Sep 23, 2025 - MLB
Sep 22, 2025 - MLB
Sep 21, 2025 - MLB
Sep 20, 2025 - MLB
Sep 19, 2025 - MLB
Chicago Cubs against Milwaukee Brewers : Head to Head (H2H)
50 %
50 %
Oct 6, 2025 - MLB
Oct 4, 2025 - MLB
Aug 21, 2025 - MLB
Aug 20, 2025 - MLB
Aug 19, 2025 - MLB
Aug 19, 2025 - MLB
Chicago Cubs - Milwaukee Brewers Key Points
- The Brewers are 3-2 ATS in their last 5 games
- The Cubs are 2-3 ATS in their last 5 games
- The Over is 3-2 in the Brewers' last 5 games
- The Over is 2-3 in the Cubs' last 5 games
Limited Offer. Currently at FanDuel
Our Chicago Cubs vs Milwaukee Brewers Prediction
Milwaukee's lineup is fronted by former MVP Christian Yelich, whose return to All‑Star form included a .280 average and 25 homers. Catcher William Contreras emerged as one of the National League's best hitters at his position, batting over .300 with line‑drive power, while shortstop Willy Adames contributed 20‑plus home runs and slick fielding.
The starting rotation boasts co‑aces Corbin Burnes and Freddy Peralta; Burnes produced a sub‑3.00 ERA with elite strikeout‑to‑walk ratios, and Peralta fanned nine Cubs in Game 2, tying a franchise postseason record. Milwaukee's bullpen is strengthened by the ascension of prospect Jacob Misiorowski, a late‑season call‑up who has consistently hit triple digits on the radar gun and locked down multiple‑inning saves.
The Cubs counter with a core built around multi‑position slugger Christopher Morel, who topped 30 homers, and second baseman Nico Hoerner, whose high contact rate and speed set the table. Chicago's rotation features left‑hander Justin Steele, one of the league ERA leaders, and veteran Jameson Taillon; however, both have lacked run support in the series.
For the Cubs to extend the matchup, their offense must strike early and often against Milwaukee's starters, and the bullpen needs to stem the Brewers' late‑inning rallies. Milwaukee's combination of frontline pitching, timely hitting and a deep relief corps makes them the favorites to complete the sweep, though the Cubs have enough talent to force a return to Milwaukee if their bats awaken. Our prediction for Chicago Cubs vs. Milwaukee Brewers: Over 6.5 runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.
