Chicago Cubs vs Milwaukee Brewers Prediction & Picks - MLB

Prediction published on 8/20/25, 4:57 PM  by Travis Pulver | Modified on 1/13/26 at 9:20 AM in MLB Picks

The Milwaukee Brewers will take on the Cubs tonight at Wrigley Field in Chicago. Fans can follow the action once the game gets underway at 8:05 p.m. EST.

After seeing their 14-game winning streak come to an end in Cincinnati, Milwaukee fans were probably hoping that the 7-0 win over the Cubs on Monday was the start of another streak. But with a pair of losses on Tuesday, the Brewers are starting to streak in the wrong direction. Jacob Misiorowski is scheduled to start for the Brewers tonight. The youngster is 4-1 this season in eight starts with a 3.89 ERA, 1.13 WHIP, and a .180 OBA. While he has been great at home, he’s had some issues on the road. He’s gone 1-1 in four starts with a 7.36 ERA and .236 OBA. In his last road start, he only lasted 1 1/3 innings vs. the Reds in Cincinnati, giving up four hits, three walks, and five earned runs while striking out three. As for the Cubs, Colin Rea will get the start. Rea has gone 9-5 with a save in 21 starts (25 appearances), he has a 3.99 ERA, and a .265 OBA.  He has gone 4-3 at home in 13 starts (14 appearances) with a 4.13 ERA and .258 OBA.