LSU Tigers vs Clemson Tigers Prediction & Picks - NCAA

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LSU Tigers
8/30/25 19:30
Clemson Tigers

Prediction:

 

Clemson ML

-178
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 by Travis Pulver in NCAA Picks

The No. 9 LSU Tigers will open the 2025 college football season on the road in Week One in South Carolina, where they will play the No. 4 Clemson Tigers. This SEC-ACC/Top Ten battle will get underway at 7:30 p.m. EST, Saturday, Aug. 30, in Memorial Stadium in Clemson, SC.

Expectations are high for LSU this season, which is not uncommon. Brian Kelly was supposed to take the team back to the elite ranks when he joined three years ago, but it hasn’t happened yet. While the Tigers could certainly gel and become a contender this season, it may be asking a bit much of these Tigers right out of the gate. Kelly has just seven returning starters, four on offense and three on defense. Now, he has the most important piece back on offense in QB Garrett Nussmeier, but his offensive line will have to be rebuilt, as well as the defense, especially the front seven. Clemson, however, will likely be better prepared to play a formidable opponent in Week One. Why? Because Dabo Swinney has eight returners back on offense and eight on defense. With just three guys to replace on each unit, there is a stronger chance they’ll gel quicker and be more successful right out of the gate.

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LSU Tigers vs Clemson Tigers Form

Table

Teams % P W D L
97
Clemson Tigers
Clemson Tigers
0 0 0 0 0
108
LSU Tigers
LSU Tigers
0 0 0 0 0

LSU Tigers and Clemson Tigers Latest Matches

LSU Tigers
LSU Tigers Latest matches
L L L W W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Dec 31, 2024 - NCAA Division I, FBS, Playoffs

Baylor Bears
31 :  44
LSU Tigers

Nov 30, 2024 - NCAA

Oklahoma Sooners
17 :  37
LSU Tigers

Nov 23, 2024 - NCAA

Vanderbilt Commodores
17 :  24
LSU Tigers

Nov 16, 2024 - NCAA

LSU Tigers
16 :  27
Florida Gators

Nov 9, 2024 - NCAA

Alabama Crimson Tide
42 :  13
LSU Tigers

Oct 26, 2024 - NCAA

LSU Tigers
23 :  38
Texas A&M Aggies
W W L W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Dec 31, 2024 - NCAA Division I, FBS, Playoffs

Baylor Bears
31 :  44
LSU Tigers

Nov 30, 2024 - NCAA

Oklahoma Sooners
17 :  37
LSU Tigers

Nov 23, 2024 - NCAA

Vanderbilt Commodores
17 :  24
LSU Tigers

Nov 9, 2024 - NCAA

Alabama Crimson Tide
42 :  13
LSU Tigers

Oct 12, 2024 - NCAA

Ole Miss Rebels
26 :  29
LSU Tigers

Sep 28, 2024 - NCAA

South Alabama Jaguars
10 :  42
LSU Tigers
L W W L L
Victories

2/5 (40%)

Draw

0/5 (0%)

Defeats

3/5 (60%)

Nov 16, 2024 - NCAA

LSU Tigers
16 :  27
Florida Gators

Oct 26, 2024 - NCAA

LSU Tigers
23 :  38
Texas A&M Aggies

Oct 19, 2024 - NCAA

LSU Tigers
34 :  10
Arkansas Razorbacks

Sep 14, 2024 - NCAA

LSU Tigers
36 :  33
South Carolina Gamecocks

Sep 1, 2024 - NCAA

LSU Tigers
20 :  27
USC Trojans
Clemson Tigers
Clemson Tigers Latest matches
W W W L W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Dec 21, 2024 - NCAA

Clemson Tigers
24 :  38
Texas Longhorns

Dec 7, 2024 - NCAA

Clemson Tigers
34 :  31
SMU Mustangs

Nov 30, 2024 - NCAA

South Carolina Gamecocks
17 :  14
Clemson Tigers

Nov 23, 2024 - NCAA

The Citadel Bulldogs
14 :  51
Clemson Tigers

Nov 16, 2024 - NCAA

Clemson Tigers
24 :  20
Pittsburgh Panthers

Nov 9, 2024 - NCAA

Clemson Tigers
24 :  14
Virginia Tech Hokies
W W W L W L
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Nov 30, 2024 - NCAA

South Carolina Gamecocks
17 :  14
Clemson Tigers

Nov 23, 2024 - NCAA

The Citadel Bulldogs
14 :  51
Clemson Tigers

Nov 2, 2024 - NCAA

Louisville Cardinals
33 :  21
Clemson Tigers

Oct 19, 2024 - NCAA

Virginia Cavaliers
31 :  48
Clemson Tigers

Sep 28, 2024 - NCAA

Stanford Cardinal
14 :  40
Clemson Tigers

Sep 21, 2024 - NCAA

North Carolina State Wolfpack
35 :  59
Clemson Tigers
W W W W W L
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Dec 21, 2024 - NCAA

Clemson Tigers
24 :  38
Texas Longhorns

Dec 7, 2024 - NCAA

Clemson Tigers
34 :  31
SMU Mustangs

Nov 16, 2024 - NCAA

Clemson Tigers
24 :  20
Pittsburgh Panthers

Nov 9, 2024 - NCAA

Clemson Tigers
24 :  14
Virginia Tech Hokies

Oct 12, 2024 - NCAA

Clemson Tigers
49 :  14
Wake Forest Demon Deacons

Oct 5, 2024 - NCAA

Clemson Tigers
29 :  13
Florida State Seminoles

LSU Tigers - Clemson Tigers Key Points

  1. LSU leads the all-time series vs. Clemson 3-1; all prior games have been in the postseason with the last being the 2019 CFP National Championship Game (42-25, LSU).
  2. Since then, LSU has lost it’s last five season openers; Clemson lost its last two (vs. Georgia and Duke) 62-10.
  3. Clemson has made the CFP seven times, played in the national title game four times, and won twice; LSU has made the CFP once and won the national championship.
  4. Betting Public: 77% of moneyline tickets and 47% of the handle are on Clemson.
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Our LSU Tigers vs Clemson Tigers Prediction

LSU has the bones of a good team, but they just haven’t played together yet. That is going to matter against another good, talented team that has played together before. There is a lot of talent on both sides of the ball for both teams, but the deciding factor will be Clemson’s veteran offensive line (four returning starters), which will give Cade Klubnik the time he needs.

Our LSU vs. Clemson Pick: Clemson ML

Prediction:

 

Clemson ML

-178
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

LSU Tigers vs Clemson Tigers Picks
Up to $300 to bet on LSU Tigers - Clemson Tigers! 

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