Jacksonville Jaguars vs Los Angeles Rams Prediction & Picks - NFL

Prediction published on 10/19/25, 6:09 AM  by Erik Gibbs | Modified on 10/19/25 at 12:55 PM in NFL Picks

The Jacksonville Jaguars (4-2) head overseas to London for a Week 7 matchup with the Los Angeles Rams (4-2), hoping to bounce back from a disappointing home loss to the Seattle Seahawks. After an impressive offensive showing in Week 5 against the Kansas City Chiefs, Jacksonville's attack lost momentum last week — something they can't afford against a fierce Rams defense.

Quarterback Trevor Lawrence will need to be at his best. His ability to move outside the pocket and extend plays will be crucial against Los Angeles' relentless pass rush. Lawrence recently mentioned that using his legs more effectively can open up the field and keep opposing defenses guessing — a strategy that could prove essential at Wembley.

Meanwhile, the Rams continue to quietly build an impressive campaign. Veteran quarterback Matthew Stafford, now surpassing Dan Marino's career total of 61,361 passing yards, has climbed into historic territory with 61,493 yards. More importantly, Stafford's play has been composed and mistake-free, providing stability to a balanced Rams offense.

On the defensive side, Los Angeles has been equally dominant. After shutting down the Baltimore Ravens, the Rams will aim to bring that same intensity to London. Their defensive front has been exceptional at creating pressure, posing a significant challenge for Jacksonville's offensive line.