Pittsburgh Pirates vs Los Angeles Dodgers Prediction & Picks - MLB

Prediction published on 9/3/25, 3:08 PM  by Lou Aguila | Modified on 2/3/26 at 8:35 AM in MLB Picks

The Los Angeles Dodgers will try to avoid a second straight loss at the hands of the Pittsburgh Pirates on Wednesday at PNC Park.

The Dodgers, who will be starting two-way star Shohei Ohtani, are listed as -180 favorites.

Current Form:

The Dodgers are still clinging to a 2.5-game lead on the San Diego Padres in the NL West title race despite dropping three of their last four games. Over the last five games, Los Angeles has pitched a 4.70 ERA and batted .233 with 3.8 runs per game. The Dodgers are still missing third baseman Max Muncy (oblique) and second baseman Tommy Edman (ankle), who are still on the 10-day injury list.

The Pirates are still last in their division with a 62-77 record, but this team has shown flashes of its ridiculous potential over the past several weeks, especially in the last 10 games, during which they have posted an elite 2.87 ERA and 1.07 WHIP. Pittsburgh has compiled a 23-19 record after the All-Star break.

Pitchers Matchup: Dodgers RHP Shohei Ohtani (1-1, 4.18 ERA) vs. Braxton Ashcraft (4-2, 2.58 ERA).