Cleveland Guardians vs Los Angeles Angels Prediction & Picks - MLB

USA - MLB

Cleveland Guardians
5/12/26 18:10
Los Angeles Angels

Prediction:

 

The Angels will win

+118
$250 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Lou Aguila | in MLB Picks

The Los Angeles Angels target a Game 2 upset win over the Cleveland Guardians with Walbert Urena looking to dominate his duel with Slade Cecconi on Tuesday.

Current Form:

The Cleveland Guardians claimed Game 1 of their series with the Los Angeles Angels, 7-2, after Joey Cantillo pitched for six scoreless innings and rookie Travis Bazzana delivered a two-run double in the third to cap a decisive 7-0 blast through the first three innings. The Guardians, who are -140 favorites for Game 2, have won the last three meetings with the Angels and seven of their last 10 meetings.

Monday’s result marked the Angels’ third loss in four games, causing them to drop 10 games below .500. After giving up 7 runs to the Guardians and 14 runs to Toronto three days before, Los Angeles’s ERA jumped to 5.36 over the last five games to 4.68 in the season. The offense has also worsened over these last five games for the Angels, who average 3.5 runs per game on a .245 BA during this stretch. Los Angeles is batting .233 while averaging 4.3 runs per game in the season.

Up to $250 to bet on Cleveland Guardians - Los Angeles Angels! 

Limited Offer. Currently at Caesars Sportsbook

Cleveland Guardians vs Los Angeles Angels Form

Table

Teams Pts P W L
12 Cleveland Guardians
0.518 83 43 40
27 Los Angeles Angels
0.417 84 35 49

Cleveland Guardians and Los Angeles Angels Latest Matches

Cleveland Guardians
Cleveland Guardians Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

May 11, 2026 - MLB

Cleveland Guardians
7 :  2
Los Angeles Angels

May 10, 2026 - MLB

Cleveland Guardians
4 :  5
Minnesota Twins

May 9, 2026 - MLB

Cleveland Guardians
1 :  2
Minnesota Twins

May 8, 2026 - MLB

Cleveland Guardians
6 :  4
Minnesota Twins

May 7, 2026 - MLB

Kansas City Royals
5 :  8
Cleveland Guardians

May 6, 2026 - MLB

Kansas City Royals
1 :  3
Cleveland Guardians
L W W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 11, 2026 - MLB

Cleveland Guardians
7 :  2
Los Angeles Angels

May 10, 2026 - MLB

Cleveland Guardians
4 :  5
Minnesota Twins

May 9, 2026 - MLB

Cleveland Guardians
1 :  2
Minnesota Twins

May 8, 2026 - MLB

Cleveland Guardians
6 :  4
Minnesota Twins

Apr 29, 2026 - MLB

Cleveland Guardians
3 :  1
Tampa Bay Rays

Apr 28, 2026 - MLB

Cleveland Guardians
0 :  1
Tampa Bay Rays
W L L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 7, 2026 - MLB

Kansas City Royals
5 :  8
Cleveland Guardians

May 6, 2026 - MLB

Kansas City Royals
1 :  3
Cleveland Guardians

May 5, 2026 - MLB

Kansas City Royals
5 :  3
Cleveland Guardians

May 4, 2026 - MLB

Kansas City Royals
6 :  2
Cleveland Guardians

May 3, 2026 - MLB

Athletics
7 :  1
Cleveland Guardians

May 2, 2026 - MLB

Athletics
6 :  14
Cleveland Guardians
Los Angeles Angels
Los Angeles Angels Latest matches
W W L L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 11, 2026 - MLB

Cleveland Guardians
7 :  2
Los Angeles Angels

May 10, 2026 - MLB

Toronto Blue Jays
1 :  6
Los Angeles Angels

May 9, 2026 - MLB

Toronto Blue Jays
14 :  1
Los Angeles Angels

May 8, 2026 - MLB

Toronto Blue Jays
2 :  0
Los Angeles Angels

May 6, 2026 - MLB

Los Angeles Angels
8 :  2
Chicago White Sox

May 5, 2026 - MLB

Los Angeles Angels
4 :  3
Chicago White Sox
L W L L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

May 6, 2026 - MLB

Los Angeles Angels
8 :  2
Chicago White Sox

May 5, 2026 - MLB

Los Angeles Angels
4 :  3
Chicago White Sox

May 4, 2026 - MLB

Los Angeles Angels
0 :  6
Chicago White Sox

May 3, 2026 - MLB

Los Angeles Angels
1 :  5
New York Mets

May 2, 2026 - MLB

Los Angeles Angels
4 :  3
New York Mets

May 1, 2026 - MLB

Los Angeles Angels
3 :  4
New York Mets
L L L L W L
Victories

1/6 (17%)

Defeats

5/6 (83%)

May 11, 2026 - MLB

Cleveland Guardians
7 :  2
Los Angeles Angels

May 10, 2026 - MLB

Toronto Blue Jays
1 :  6
Los Angeles Angels

May 9, 2026 - MLB

Toronto Blue Jays
14 :  1
Los Angeles Angels

May 8, 2026 - MLB

Toronto Blue Jays
2 :  0
Los Angeles Angels

Apr 29, 2026 - MLB

Chicago White Sox
3 :  2
Los Angeles Angels

Apr 28, 2026 - MLB

Chicago White Sox
5 :  2
Los Angeles Angels

Cleveland Guardians against Los Angeles Angels : Head to Head (H2H)

Cleveland Guardians

50 %

Los Angeles Angels

50 %

May 11, 2026 - MLB

Cleveland Guardians
7 :  2
Los Angeles Angels

Mar 13, 2026 - MLB Spring Training

Los Angeles Angels
5 :  2
Cleveland Guardians

Mar 6, 2026 - MLB Spring Training

Cleveland Guardians
5 :  3
Los Angeles Angels

Apr 6, 2025 - MLB

Los Angeles Angels
6 :  2
Cleveland Guardians

Apr 5, 2025 - MLB

Los Angeles Angels
10 :  4
Cleveland Guardians

Apr 4, 2025 - MLB

Los Angeles Angels
6 :  8
Cleveland Guardians

Cleveland Guardians - Los Angeles Angels Key Points

  1. LA Angels is 3-9 SU in its last 12 games against Cleveland.
  2. Cleveland is 4-2 SU in its last 6 games.
  3. Angels RHP Walbert Urena has allowed one earned run in back-to-back starts
  4. Guardians RHP Slade Cecconi has surrendered a total of 12 earned runs in two career starts vs. the Angels
Up to $250 to bet on Cleveland Guardians - Los Angeles Angels! 

Limited Offer. Currently at Caesars Sportsbook

Our Cleveland Guardians vs Los Angeles Angels Prediction

Upset Alert: Behind another stellar showing from Walbert Urena, the Angels will grind out a hard-earned win in Game 2, snapping their three-game losing streak against the Guardians. Urena (1-3, 3.22 ERA) has allowed only one run in back-to-back starts, lowering his ERA to 3.48 over 5 innings over his last five starts. Urena is expected to gain the upper hand in his duel with Guardians RHP Slade Cecconi (2-3, 6.15 ERA), who has surrendered 18 earned runs over his last four starts. Cecconi bungled up with seven earned runs in his first start against the Angels on June 12, 2024, and yielded five earned runs in the second run-in with Los Angeles on May 31, 2025.

Best Pick: Go for the Angels at +118. As discussed above, Urena is oozing with confidence coming into his start against the Guardians. He should help the Angels establish an early lead with some assists from the batters. Los Angeles isn’t scoring much this season, but they average 1.2 home runs and sport a decent .310 OBP this season. It all just takes one big swing from any of their heavy hitters, including Mike Trout, to change the complexion of this game.

Our betting prediction for the Los Angeles Angels vs. the Cleveland Guardians: The Angels will win.

Prediction:

 

The Angels will win

+118
$250 offered for betting!

Caesars Rewards Program

Caesars Rewards

Caesars Sportsbook really spoils new users with an awesome rewards program, making every wager count towards something bigger! Available for users across the country, this program is a bettor's dream. As you enjoy the thrills of sports betting or casino games online, you can earn up to 10 Reward Credits for every $100 wagered on straight bets. And if parlays are more your style, you'll earn up to 20 Reward Credits for every $100 wagered. With Caesars Sportsbook, your bets not only bring the excitement of the game but also the joy of accumulating rewards that enhance your gaming experience. Play now and let Caesars treat you like royalty with each bet you place!

Sign-up now!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Cleveland Guardians vs Los Angeles Angels Picks