Lorenzo Musetti vs Yannick Hanfmann Prediction & Picks - Brussels Open

ATP - Brussels Open

ATP 8 Italy
Lorenzo Musetti
10/16/25 12:40
ATP 139 Germany
Yannick Hanfmann

Prediction:

 

Yannick Hanfmann +2.5 Games

+115
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 by Lou Aguila in Tennis Picks

Lorenzo Musetti of Italy will tangle with Yannick Hanfmann of Germany for a place in the quarterfinals of the 2025 European Open in Brussels, Belgium, on Thursday.

Ranked No.8 in the world, Musetti will march into his fifth career match with Hanfmann as a -270 favorite. However, the German is on a tear as of late, going 7-1 in his last 8 matches.

Current Form:

Musetti is scheduled to play his first match in Brussels after receiving a bye into the second round. Seeded No.1 in the ATP 250 Indoor Brussels, Musetti faces a familiar face in his opening match as he takes on Hanfmann, who currently ranks outside the ATP top-100 but is armed with experience in playing against top-caliber opponents. The Italian is 18-11 on the hard court and 37-16 on the hard court in 2025.

Again, Hanfmann has been playing well over the past three weeks, winning seven of his last eight matches. The German picked up four wins in Shanghai, two of which were from the qualifiers, to reach the quarterfinals of the ATP 1000 event, where he pushed Novak Djokovic to the limit in a gallant losing effort 6-4, 5-7, 3-6. Hanfmann had ridden his momentum into the qualifying stage in Brussels, where he registered wins over Calvin Hemery of France and Tibo Colson of Belgium. In the first round, Hanfmann rallied from a set down to beat Matteo Arnaldi 6-7, 6-4, 6-4.

Lorenzo Musetti vs Yannick Hanfmann Form

Lorenzo Musetti and Yannick Hanfmann Latest Matches

Lorenzo Musetti Latest matches
W W L W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 8, 2025 - ATP Shanghai Masters

Felix Auger Aliassime
2 :  0
Lorenzo Musetti

Oct 6, 2025 - ATP Shanghai Masters

Luciano Darderi
0 :  2
Lorenzo Musetti

Oct 4, 2025 - ATP Shanghai Masters

Francisco Comesana
0 :  2
Lorenzo Musetti

Sep 29, 2025 - ATP Beijing Open

Learner Tien
abort
Lorenzo Musetti

Sep 28, 2025 - ATP Beijing Open

Adrian Mannarino
0 :  2
Lorenzo Musetti

Sep 26, 2025 - ATP Beijing Open

Giovanni Mpetshi Perricard
1 :  2
Lorenzo Musetti
Yannick Hanfmann Latest matches
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Oct 15, 2025 - Brussels Open

Yannick Hanfmann
2 :  1
Matteo Arnaldi

Oct 13, 2025 - Brussels Open

Tibo Colson
1 :  2
Yannick Hanfmann

Oct 12, 2025 - Brussels Open

Calvin Hemery
0 :  2
Yannick Hanfmann

Oct 5, 2025 - ATP Shanghai Masters

Yannick Hanfmann
1 :  2
Novak Djokovic

Oct 3, 2025 - ATP Shanghai Masters

Frances Tiafoe
1 :  2
Yannick Hanfmann

Oct 1, 2025 - ATP Shanghai Masters

Lorenzo Sonego
1 :  2
Yannick Hanfmann

Lorenzo Musetti against Yannick Hanfmann : Head to Head (H2H)

Lorenzo Musetti

50 %

Yannick Hanfmann

50 %

May 25, 2025 - ATP French Open

Lorenzo Musetti
3 :  0
Yannick Hanfmann

Apr 28, 2023 - ATP Mutua Madrid Open

Yannick Hanfmann
2 :  0
Lorenzo Musetti
Compare Lorenzo Musetti and Yannick Hanfmann with our comparison tool.

Lorenzo Musetti - Yannick Hanfmann Key Points

  1. Yannick Hanfmann defeated Matteo Arnaldi 6-7, 6-4, 6-4 in the first round of the 2025 ATP Brussels.
  2. Yannick Hanfmann is 7-1 in his last 8 matches.
  3. Lorenzo Musetti is the No.1 seed at the 2025 ATP Brussels.
  4. Lorenzo Musetti is 2-2 vs. Yannick Hanfmann in their head-to-head series.

Our Lorenzo Musetti vs Yannick Hanfmann Prediction

Hanfmann parades a 5-0 record in indoor matches in 2025, while Musetti hasn’t played an indoor match this year and only carries a 44 percent win rate in this type of playing environment. Hanfmann is 0-4 against the top-10 players in 2025, but he just pushed Novak Djokovic to the limit in their recent tussle in Shanghai. Hanfmann has a 55 percent win in indoor matches.

Fearless Forecast: Yannick Hanfmann seems like a worthy pick to cover +2.5 games (+115). Although this is the first time he will be playing Musetti on a surface other than the clay court, Hanfmann is equipped with the top-tier skills and experience to go toe-to-toe with the world’s No.8. Musetti might still grind out a win in the end, but I believe he will need to go through the eye of a needle to get past Hanfmann, who is undefeated in indoor matches this year.

Our betting prediction for Yannick Hanfmann vs. Lorenzo Musetti: Yannick Hanfmann +2.5 Games

Prediction:

 

Yannick Hanfmann +2.5 Games

+115
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Lorenzo Musetti vs Yannick Hanfmann Picks