Lazio vs Roma Prediction & Picks - Serie A

Italy - Serie A

Lazio
9/21/25 06:30
Roma

Prediction:

 

Roma wins the match

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 by Tyler Doty in Serie A Picks

We're in for a Roman derby on matchday 4 of Serie A! This Sunday, Lazio Rome and AS Roma will face off at the Stadio Olimpico. It's one of the must-see matches of every season in the Italian league. Lazio are already up against the wall at the start of the season, having lost twice in just three games. Maurizio Sarri's team are currently in 12th place in the standings and cannot afford any more mistakes if they don't want to fall too far behind in the race for Europe.

AS Roma, meanwhile, is a little higher up in the Serie A standings, sitting in 6th place. The Giallorossi have managed to pick up six points from their first three league games. Now under the leadership of Gian Piero Gasperini, they are hoping to make a big statement by winning the derby. This would also give them a confidence boost ahead of their Europa League trip to OGC Nice.

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Lazio vs Roma Form

Table

Teams Pts P W D L GD
6
Roma
Roma
6 3 2 0 1 1
12
Lazio
Lazio
3 3 1 0 2 1

Lazio and Roma Latest Matches

Lazio
Lazio Latest matches
D W W L W L
Victories

3/6 (50%)

Draw

1/6 (17%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

2.33 Total goals
17% BTTS
1.5 Goals scored
0.83 Goals conceded
33% Over 2.5
67% Under 2.5

Sep 14, 2025 - Serie A

Sassuolo
1 :  0
Lazio

Aug 31, 2025 - Serie A

Lazio
4 :  0
Hellas Verona

Aug 24, 2025 - Serie A

Como 1907
2 :  0
Lazio

Aug 16, 2025 - Clubs Friendlies

Lazio
2 :  0
Atromitos Athinon

Aug 9, 2025 - Clubs Friendlies

Burnley
0 :  1
Lazio

Aug 2, 2025 - Clubs Friendlies

Galatasaray
2 :  2
Lazio
D D L W W W
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

2.33 Total goals
33% BTTS
1.67 Goals scored
0.67 Goals conceded
33% Over 2.5
67% Under 2.5

Aug 31, 2025 - Serie A

Lazio
4 :  0
Hellas Verona

Aug 16, 2025 - Clubs Friendlies

Lazio
2 :  0
Atromitos Athinon

Jul 26, 2025 - Clubs Friendlies

Lazio
1 :  0
Avellino

May 25, 2025 - Serie A

Lazio
0 :  1
Lecce

May 10, 2025 - Serie A

Lazio
1 :  1
Juventus

Apr 28, 2025 - Serie A

Lazio
2 :  2
Parma
D L D W L L
Victories

1/6 (17%)

Draw

2/6 (33%)

Defeats

3/6 (50%)

Average stats (Last 6 matchs)

2.17 Total goals
33% BTTS
0.83 Goals scored
1.33 Goals conceded
33% Over 2.5
67% Under 2.5

Sep 14, 2025 - Serie A

Sassuolo
1 :  0
Lazio

Aug 24, 2025 - Serie A

Como 1907
2 :  0
Lazio

Aug 9, 2025 - Clubs Friendlies

Burnley
0 :  1
Lazio

Aug 2, 2025 - Clubs Friendlies

Galatasaray
2 :  2
Lazio

Jul 30, 2025 - Clubs Friendlies

Fenerbahce Istanbul
1 :  0
Lazio

May 18, 2025 - Serie A

Inter Milan
2 :  2
Lazio
Roma
Roma Latest matches
L W D W W L
Victories

3/6 (50%)

Draw

1/6 (17%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

2 Total goals
17% BTTS
0.83 Goals scored
1.17 Goals conceded
33% Over 2.5
67% Under 2.5

Sep 14, 2025 - Serie A

Roma
0 :  1
Torino FC

Aug 30, 2025 - Serie A

Pisa SC
0 :  1
Roma

Aug 23, 2025 - Serie A

Roma
1 :  0
Bologna

Aug 16, 2025 - Clubs Friendlies

Roma
2 :  2
Neom SC

Aug 9, 2025 - Clubs Friendlies

Everton
0 :  1
Roma

Aug 6, 2025 - Clubs Friendlies

Aston Villa
4 :  0
Roma
W W W D W L
Victories

4/6 (67%)

Draw

1/6 (17%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

2.33 Total goals
33% BTTS
1.67 Goals scored
0.67 Goals conceded
50% Over 2.5
50% Under 2.5

Sep 14, 2025 - Serie A

Roma
0 :  1
Torino FC

Aug 23, 2025 - Serie A

Roma
1 :  0
Bologna

Aug 16, 2025 - Clubs Friendlies

Roma
2 :  2
Neom SC

Jul 31, 2025 - Clubs Friendlies

Roma
3 :  0
AS Cannes

May 18, 2025 - Serie A

Roma
3 :  1
AC Milan

May 4, 2025 - Serie A

Roma
1 :  0
Fiorentina
W W W L W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

1.83 Total goals
0% BTTS
1.17 Goals scored
0.67 Goals conceded
17% Over 2.5
83% Under 2.5

Aug 30, 2025 - Serie A

Pisa SC
0 :  1
Roma

Aug 9, 2025 - Clubs Friendlies

Everton
0 :  1
Roma

Aug 6, 2025 - Clubs Friendlies

Aston Villa
4 :  0
Roma

Aug 2, 2025 - Clubs Friendlies

Lens
0 :  2
Roma

Jul 26, 2025 - Clubs Friendlies

Kaiserslautern
0 :  1
Roma

May 25, 2025 - Serie A

Torino FC
0 :  2
Roma

Lazio against Roma : Head to Head (H2H)

Lazio

33 %

Draw

33 %

Roma

33 %

Average stats (last H2H results)

1.17
Total goals
17%
BTTS
0.5
Goals scored (Team 1)
0.67
Goals scored (Team 2)
0%
Over 2.5
100%
Under 2.5

Apr 13, 2025 - Serie A

Lazio
1 :  1
Roma

Jan 5, 2025 - Serie A

Roma
2 :  0
Lazio

Apr 6, 2024 - Serie A

Roma
1 :  0
Lazio

Jan 10, 2024 - Coppa Italia

Lazio
1 :  0
Roma

Nov 12, 2023 - Serie A

Lazio
0 :  0
Roma

Mar 19, 2023 - Serie A

Lazio
1 :  0
Roma

Lazio - Roma: Form Analysis

It hasn't been the ideal start to the season for Lazio Rome. Having failed to qualify for Europe last season, the Lazio club is hoping to bounce back in the coming months. However, it got off to a rocky start, losing 2-0 to Como. Maurizio Sarri's team bounced back the following day with an easy 4-0 win over Hellas Verona. However, they slipped back into their old ways last Sunday, losing 1-0 away to newly promoted Sassuolo. The tifosi were quick to express their dissatisfaction after this setback.

Lazio Rome has already lost twice in just three Serie A games.

AS Roma has been a little more convincing so far. Without necessarily shining, the Giallorossi have picked up maximum points from their first two games, winning against Bologna (0-1) and Pisa (1-0). Last weekend, Gian Piero Gasperini's men suffered their first setback with a defeat against Torino (0-1). There is no cause for alarm yet, as they are still in sixth place in Serie A. AS Roma will certainly not want to suffer a second poor result in a row. They will therefore approach this Rome derby with high ambitions.

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Roma v Lazio last Lineups

Lazio

Formation : 4 - 3 - 3

94
I. Provedel
77
A. Marusic
34
M. Gila
13
A. Romagnoli
17
N. Tavares
8
M. Guendouzi
6
N. Rovella
7
F. Dele-Bashiru
22
M. Cancellieri
11
T. Castellanos
10
M. Zaccagni
21
P. Dybala
8
N. El Aynaoui
18
M. Soule
3
Angelino
17
M. Kone
4
B. Cristante
43
Wesley
5
E. Ndicka
23
G. Mancini
22
M. Hermoso
99
M. Svilar

Formation : 3 - 4 - 2 - 1

Roma

Missing players

Lazio
Lazio
Defender

Patric

S. Gigot

Midfielder

M. Lazzari

M. Vecino

N. Rovella

Forward

T. Castellanos

Roma
Roma
Forward

L. Bailey

P. Dybala

Lazio & Roma Squad Analysis

Lazio Rome will have a few players missing for this derby. Patric, Manuel Lazzari, and Matias Vecino are out, while Nicolo Rovella is uncertain. So far, Lazio has only scored in one game in this Serie A season. That was on matchday 2 against Hellas Verona, when they scored four goals. During that match, Taty Castellanos stood out. In addition to two assists, he managed to score one goal. In midfield, Mattéo Guendouzi knows he is eagerly awaited. The French midfielder hopes to put on a great performance to help his team get back on track in the league.

Paulo Dybala is out for this derby for AS Roma.

As for AS Roma, Edoardo Bove, Leon Bailey, and Paulo Dybala are unavailable. However, the Giallorossi can still rely on a very solid defense, having conceded only one goal in three Serie A games. Mile Svilar is one of the best goalkeepers in the Italian league and is expected to shine again this weekend. In midfield, Manu Koné has been outstanding. The French midfielder has no intention of taking his foot off the gas for such a highly anticipated fixture. Signed during the last summer transfer window, Evan Ferguson is waiting to open his goalscoring account. So far, the Irish striker has only managed one assist.

Most goals and assists

CD Huachipato Lazio
CD Huachipato Roma
Top Goalscorer
Italy M. Zaccagni (1 Goals)
France M. Guendouzi (1 Goals)
Argentina T. Castellanos (1 Goals)
Senegal B. Dia (1 Goals)
Top Goalscorer
Brazil Wesley (1 Goals) Argentina M. Soule (1 Goals)
Best assists
Argentina T. Castellanos (2 Assists)
Best assists
Rep. of Ireland E. Ferguson (1 Assists)

Lazio and Roma Stats in Serie A

Lazio
Lazio
Roma
Roma
33%
Victories
67%
0%
Draw
0%
67%
Defeats
33%
2.33
Total goals per match
1
1.33
Goals scored per match
0.67
1
Goals conceded per match
0.33
33%
Over 2.5
0%
67%
Under 2.5
100%
0%
BTTS
0%
33%
No goals conceded
67%

Lazio - Roma Key Points

  1. AS Roma has won two of its first three Serie A matches.
  2. AS Roma has won two of the last three Rome derbies.
  3. AS Roma wants to build confidence ahead of its Europa League debut.
  4. Lazio Rome has lost two of its three Serie A matches.
  5. Lazio Rome fans expressed their dissatisfaction after their team's latest defeat away to newly promoted Sassuolo (1-0).
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Our Lazio vs Roma Prediction

Lazio Rome is not in the best shape going into this derby against AS Roma. Maurizio Sarri's men have just handed Sassuolo their first win of the season (1-0). They will struggle to bounce back in a match that their tifosi are eagerly awaiting. The Giallorossi have been much more convincing so far. The team coached by Gian Piero Gasperini has won two of its first three Serie A games and will certainly not be taking its foot off the gas this Sunday afternoon in Rome!

Our prediction for Lazio Rome vs AS Roma: AS Roma to win!

Prediction:

 

Roma wins the match

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Lazio vs Roma - Other Interesting Picks

Under 2.5 Goals

Odds -164
Roman derbies are rarely prolific affairs. The “under 2.5 goals in the match” bet has passed in the last seven encounters between the two rivals. This could well be the case again this weekend.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

Lazio vs Roma Picks
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