Houston Astros vs Kansas City Royals Prediction & Picks - MLB

USA - MLB

Houston Astros
9/17/26 19:15
Kansas City Royals

Prediction:

 

Run in 1st Inning - No

+105
$250 offered for betting!

New customers only | Commercial content | 21+ age limit | T&Cs apply

 by Edgar Jibran | in MLB Picks

The 2026 MLB season has been a rollercoaster for the Houston Astros, and the final stretch promises absolute insanity as they battle the Texas Rangers for the AL West Divisional Championship. With that in mind, the Astros will need full engagement in the final game of the series against the Kansas City Royals to secure a win that keeps away the Rangers from surpassing them in the standings.

In this regard, it could be surprising to see the Houston Astros pick Miguel Ullola to start this game; however, the Dominican has proven to be one of the most solid relievers this season. In fact, he allowed earned runs in only one of his six appearances this season, so he’s expected to keep the first inning under control.

Meanwhile, the Kansas City Royals made a more solid decision for this game, as they will start Seth Lugo, who is the third-best pitcher on the Royals’ roster in strikeouts (126), but it cannot be ignored that in three of his last six starts, he allowed 5 or more earned runs. Furthermore, he recorded more than 5 strikeouts in only one of his last eleven starts.

Up to $250 to bet on Houston Astros - Kansas City Royals! 

Limited Offer. Currently at Caesars Sportsbook

Houston Astros vs Kansas City Royals Form

Table

Teams Pts P W L
13 Houston Astros
0.5 154 77 77
26 Kansas City Royals
0.435 154 67 87

Houston Astros and Kansas City Royals Latest Matches

Houston Astros
Houston Astros Latest matches
L W L L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 15, 2026 - MLB

Houston Astros
4 :  2
Kansas City Royals

Sep 13, 2026 - MLB

Tampa Bay Rays
14 :  4
Houston Astros

Sep 12, 2026 - MLB

Tampa Bay Rays
3 :  2
Houston Astros

Sep 11, 2026 - MLB

Tampa Bay Rays
3 :  1
Houston Astros

Sep 10, 2026 - MLB

Philadelphia Phillies
1 :  2
Houston Astros

Sep 9, 2026 - MLB

Philadelphia Phillies
11 :  7
Houston Astros
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 15, 2026 - MLB

Houston Astros
4 :  2
Kansas City Royals

Sep 6, 2026 - MLB

Houston Astros
2 :  3
Arizona Diamondbacks

Sep 5, 2026 - MLB

Houston Astros
3 :  4
Arizona Diamondbacks

Sep 4, 2026 - MLB

Houston Astros
3 :  1
Arizona Diamondbacks

Sep 3, 2026 - MLB

Houston Astros
6 :  2
Chicago White Sox

Sep 2, 2026 - MLB

Houston Astros
2 :  0
Chicago White Sox
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 13, 2026 - MLB

Tampa Bay Rays
14 :  4
Houston Astros

Sep 12, 2026 - MLB

Tampa Bay Rays
3 :  2
Houston Astros

Sep 11, 2026 - MLB

Tampa Bay Rays
3 :  1
Houston Astros

Sep 10, 2026 - MLB

Philadelphia Phillies
1 :  2
Houston Astros

Sep 9, 2026 - MLB

Philadelphia Phillies
11 :  7
Houston Astros

Sep 8, 2026 - MLB

Philadelphia Phillies
5 :  6
Houston Astros
Kansas City Royals
Kansas City Royals Latest matches
L W W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 15, 2026 - MLB

Houston Astros
4 :  2
Kansas City Royals

Sep 13, 2026 - MLB

Boston Red Sox
4 :  1
Kansas City Royals

Sep 12, 2026 - MLB

Boston Red Sox
5 :  1
Kansas City Royals

Sep 11, 2026 - MLB

Boston Red Sox
2 :  3
Kansas City Royals

Sep 9, 2026 - MLB

Kansas City Royals
5 :  2
Arizona Diamondbacks

Sep 8, 2026 - MLB

Kansas City Royals
3 :  5
Arizona Diamondbacks
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 9, 2026 - MLB

Kansas City Royals
5 :  2
Arizona Diamondbacks

Sep 8, 2026 - MLB

Kansas City Royals
3 :  5
Arizona Diamondbacks

Sep 7, 2026 - MLB

Kansas City Royals
4 :  5
Arizona Diamondbacks

Sep 6, 2026 - MLB

Kansas City Royals
6 :  1
Toronto Blue Jays

Sep 5, 2026 - MLB

Kansas City Royals
3 :  4
Toronto Blue Jays

Sep 4, 2026 - MLB

Kansas City Royals
2 :  9
Toronto Blue Jays
W L W L L L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 15, 2026 - MLB

Houston Astros
4 :  2
Kansas City Royals

Sep 13, 2026 - MLB

Boston Red Sox
4 :  1
Kansas City Royals

Sep 12, 2026 - MLB

Boston Red Sox
5 :  1
Kansas City Royals

Sep 11, 2026 - MLB

Boston Red Sox
2 :  3
Kansas City Royals

Aug 30, 2026 - MLB

Cleveland Guardians
11 :  1
Kansas City Royals

Aug 29, 2026 - MLB

Cleveland Guardians
3 :  8
Kansas City Royals

Houston Astros against Kansas City Royals : Head to Head (H2H)

Houston Astros

83 %

Kansas City Royals

17 %

Sep 15, 2026 - MLB

Houston Astros
4 :  2
Kansas City Royals

Jun 14, 2026 - MLB

Kansas City Royals
4 :  0
Houston Astros

Jun 13, 2026 - MLB

Kansas City Royals
7 :  8
Houston Astros

Jun 12, 2026 - MLB

Kansas City Royals
8 :  10
Houston Astros

May 14, 2025 - MLB

Houston Astros
4 :  3
Kansas City Royals

May 13, 2025 - MLB

Houston Astros
2 :  1
Kansas City Royals
Houston Astros vs Kansas City Royals Picks

Houston Astros - Kansas City Royals Key Points

  1. The Kansas City Royals had John Rave, who had the best hitting performance in the second game of the series against the Astros, with a two-run home run.
  2. The Houston Astros had Jeremy Peña, the only player to record more than two hits in the second game of the series against the Royals.
  3. The Kansas City Royals have Carter Jensen and Jac Caglianone, the top performers on the roster, both with more than 20 home runs recorded this season.
  4. The Houston Astros will start their second game of the season with Miguel Ullola as the opener, so he isn’t expected to throw more than 20 pitches.
Up to $250 to bet on Houston Astros - Kansas City Royals! 

Limited Offer. Currently at Caesars Sportsbook

Our Houston Astros vs Kansas City Royals Prediction

As given, the Astros will face this last game of the series against the Royals in a very particular way; however, it cannot be ignored that the last time they tried something similar was during their 3-1 loss to the Tampa Bay Rays a week ago.

In conclusion, even though the Kansas City Royals are one of the weakest sides in the current MLB season, they can still directly impact the outcome of the season in games like this one. Therefore, the pick for the Kansas City Royals – Houston Astros is: Run in 1st Inning - No!

Prediction:

 

Run in 1st Inning - No

+105
$250 offered for betting!

A Welcome Bonus for Houston Astros vs Kansas City Royals!

Caesars Welcome Offer

Thanks to our code:  STRADERDYW, you can unlock $250 available for use on this Houston Astros vs Kansas City Royals matchup!

This offer is only available for new sign-ups, but it remains one of the highest welcome bonuses currently on offer. Take advantage before it goes away!

$250 in bonus bets for Houston Astros vs Kansas City Royals!

All tips are fully researched and given in good faith, but profits cannot be guaranteed.