Jacksonville Jaguars vs Kansas City Chiefs Prediction & Picks - NFL

Prediction published on 10/6/25, 4:52 PM  by Travis Pulver | Modified on 10/15/25 at 6:53 AM in NFL Picks

The Kansas City Chiefs will go on the road this week to face another AFC team, the Jaguars, at Ever Bank Stadium in Jacksonville, FL. Kickoff is scheduled for 8:15 p.m. EST on Monday, October 6 and the game will be broadcast as Monday Night Football on ABC.

Fans of the Chiefs may still be riding a high after watching their team dominate the Baltimore Ravens last week, 37-20. Getting Xavier Worthy back was a real boost for the offense; Mahomes ended up targeting him eight times and he caught five for 83 yards. With the deep ball threat back, the rest of the offense seemed to open up, and the game became reminiscent of the early Mahomes days as the Chiefs QB went 25-37 for 270 yards and four touchdowns.  As for the Jaguars, Jacksonville is a surprising 3-1 with wins over Seattle and San Francisco. On offense, they have not looked impressive, but they rank No. 10 in total yards with 348.5 (204.5 passing and 144 rushing); No. 17 in scoring with 24 points per game). Their strength so far has been their defense. It ranks No. 15 in total yards (316.3 per game) but is No. 5 in scoring (18 per game).