Kansas City Chiefs vs Jacksonville Jaguars Prediction & Picks - NFL

USA - NFL

Kansas City Chiefs
10/6/25 20:15
Jacksonville Jaguars

Prediction:

 

UNDER 46.5

-120
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 by Travis Pulver in NFL Picks

The Kansas City Chiefs will go on the road this week to face another AFC team, the Jaguars, at Ever Bank Stadium in Jacksonville, FL. Kickoff is scheduled for 8:15 p.m. EST on Monday, October 6 and the game will be broadcast as Monday Night Football on ABC.

Fans of the Chiefs may still be riding a high after watching their team dominate the Baltimore Ravens last week, 37-20. Getting Xavier Worthy back was a real boost for the offense; Mahomes ended up targeting him eight times and he caught five for 83 yards. With the deep ball threat back, the rest of the offense seemed to open up, and the game became reminiscent of the early Mahomes days as the Chiefs QB went 25-37 for 270 yards and four touchdowns.  As for the Jaguars, Jacksonville is a surprising 3-1 with wins over Seattle and San Francisco. On offense, they have not looked impressive, but they rank No. 10 in total yards with 348.5 (204.5 passing and 144 rushing); No. 17 in scoring with 24 points per game). Their strength so far has been their defense. It ranks No. 15 in total yards (316.3 per game) but is No. 5 in scoring (18 per game).

Kansas City Chiefs vs Jacksonville Jaguars Form

Table

Teams % P W D L
7
Jacksonville Jaguars
Jacksonville Jaguars
0.75 4 3 0 1
19
Kansas City Chiefs
Kansas City Chiefs
0.5 4 2 0 2

Kansas City Chiefs and Jacksonville Jaguars Latest Matches

Kansas City Chiefs
Kansas City Chiefs Latest matches
W L L L W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Sep 28, 2025 - NFL

Baltimore Ravens
20 :  37
Kansas City Chiefs

Sep 21, 2025 - NFL

Kansas City Chiefs
22 :  9
New York Giants

Sep 14, 2025 - NFL

Philadelphia Eagles
20 :  17
Kansas City Chiefs

Sep 5, 2025 - NFL

Kansas City Chiefs
21 :  27
Los Angeles Chargers

Feb 9, 2025 - NFL

Kansas City Chiefs
22 :  40
Philadelphia Eagles

Jan 26, 2025 - NFL

Buffalo Bills
29 :  32
Kansas City Chiefs
W W W W L W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Sep 28, 2025 - NFL

Baltimore Ravens
20 :  37
Kansas City Chiefs

Sep 14, 2025 - NFL

Philadelphia Eagles
20 :  17
Kansas City Chiefs

Jan 26, 2025 - NFL

Buffalo Bills
29 :  32
Kansas City Chiefs

Jan 18, 2025 - NFL

Houston Texans
14 :  23
Kansas City Chiefs

Dec 21, 2024 - NFL

Houston Texans
19 :  27
Kansas City Chiefs

Dec 8, 2024 - NFL

Los Angeles Chargers
17 :  19
Kansas City Chiefs
W W L L L W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Sep 21, 2025 - NFL

Kansas City Chiefs
22 :  9
New York Giants

Sep 5, 2025 - NFL

Kansas City Chiefs
21 :  27
Los Angeles Chargers

Feb 9, 2025 - NFL

Kansas City Chiefs
22 :  40
Philadelphia Eagles

Jan 5, 2025 - NFL

Kansas City Chiefs
0 :  38
Denver Broncos

Dec 25, 2024 - NFL

Kansas City Chiefs
29 :  10
Pittsburgh Steelers

Dec 15, 2024 - NFL

Kansas City Chiefs
21 :  7
Cleveland Browns
Jacksonville Jaguars
Jacksonville Jaguars Latest matches
W L W L W W
Victories

4/6 (67%)

Draw

0/6 (0%)

Defeats

2/6 (33%)

Sep 28, 2025 - NFL

Jacksonville Jaguars
26 :  21
San Francisco 49ers

Sep 21, 2025 - NFL

Houston Texans
10 :  17
Jacksonville Jaguars

Sep 14, 2025 - NFL

Jacksonville Jaguars
27 :  31
Cincinnati Bengals

Sep 7, 2025 - NFL

Carolina Panthers
10 :  26
Jacksonville Jaguars

Jan 5, 2025 - NFL

Jacksonville Jaguars
23 :  26
Indianapolis Colts

Dec 29, 2024 - NFL

Tennessee Titans
13 :  20
Jacksonville Jaguars
L L L W W W
Victories

3/6 (50%)

Draw

0/6 (0%)

Defeats

3/6 (50%)

Sep 21, 2025 - NFL

Houston Texans
10 :  17
Jacksonville Jaguars

Sep 7, 2025 - NFL

Carolina Panthers
10 :  26
Jacksonville Jaguars

Dec 29, 2024 - NFL

Tennessee Titans
13 :  20
Jacksonville Jaguars

Dec 15, 2024 - NFL

New York Jets
32 :  25
Jacksonville Jaguars

Dec 1, 2024 - NFL

Houston Texans
23 :  20
Jacksonville Jaguars

Nov 10, 2024 - NFL

Minnesota Vikings
12 :  7
Jacksonville Jaguars
L W L L L W
Victories

2/6 (33%)

Draw

0/6 (0%)

Defeats

4/6 (67%)

Sep 28, 2025 - NFL

Jacksonville Jaguars
26 :  21
San Francisco 49ers

Sep 14, 2025 - NFL

Jacksonville Jaguars
27 :  31
Cincinnati Bengals

Jan 5, 2025 - NFL

Jacksonville Jaguars
23 :  26
Indianapolis Colts

Dec 22, 2024 - NFL

Jacksonville Jaguars
14 :  19
Las Vegas Raiders

Dec 8, 2024 - NFL

Jacksonville Jaguars
10 :  6
Tennessee Titans

Nov 17, 2024 - NFL

Jacksonville Jaguars
6 :  52
Detroit Lions

Kansas City Chiefs against Jacksonville Jaguars : Head to Head (H2H)

Jan 21, 2023 - NFL

Jacksonville Jaguars
20 :  27
Kansas City Chiefs

Kansas City Chiefs - Jacksonville Jaguars Key Points

  1. Kansas City leads the all-time series vs. Jacksonville 10-6.
  2. The Chiefs have won the last eight meetings with the Jaguars; Jacksonville’s last win vs. the Chiefs was in 2009.
  3. Betting Public: 93% of moneyline tickets are backing the Chiefs to win outright, but only 67% of spread tickets are backing them to win ATS.
  4. Betting Public: 39% of TOTAL tickets and 28% of the handle are on the UNDER.

Our Kansas City Chiefs vs Jacksonville Jaguars Prediction

Kansas City owned the Jaguars for years, but this year’s KC team has been vulnerable. The offense was fantastic against a beaten and battered Baltimore defense, but the Jaguars have been stingy with points this season. Jacksonville has been one of the better run teams in the league this year (144 ypg); the Chiefs have struggled to stop the run (127 ypg allowed). I’m not confident in either team to win, but I do think the Jaguars will run the ball well against the Chiefs and eat up a lot of clock. Because of that, I’m going with the UNDER.

Our Chiefs vs. Jaguars Pick: UNDER 46.5

Prediction:

 

UNDER 46.5

-120
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Kansas City Chiefs vs Jacksonville Jaguars Picks