James Madison Dukes vs Oregon Ducks Prediction & Picks - NCAA

USA - NCAA

James Madison Dukes
12/20/25 19:30
Oregon Ducks

Prediction:

 

James Madison Dukes +21.5 Alternate Spread

-131
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 by Matt Lowrimore in NCAA Picks

The final College Football Playoff first-round game will see the 12th-seeded James Madison Dukes take on the 5th-seeded Oregon Ducks. Let’s take a look at the match statistics and predictions for this game between the Dukes and the Ducks. 

James Madison enters this game having finished the regular season with a record of 12-1. The Dukes most recently beat the Troy Trojans in the Sun Belt Championship by a score of 31-14. James Madison’s offense had a total of 411 yards, while its defense allowed 177 yards. Quarterback Alonza Barnett III threw for 93 yards, one touchdown, and one interception, while running back Wayne Knight led the team in rushing with 212 yards and one touchdown.

As for Oregon, they enter this game having finished the regular season with a record of 11-1. The Ducks most recently beat the Washington Huskies by a score of 26-14 back in Week 14. Oregon’s offense had a total of 392 yards, while its defense allowed 283 yards. Quarterback Dante Moore threw for 286 yards and one touchdown, while running back Noah Whittington led the team in rushing with 47 yards.

James Madison Dukes vs Oregon Ducks Form

James Madison Dukes and Oregon Ducks Latest Matches

James Madison Dukes
James Madison Dukes Latest matches
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Dec 5, 2025 - NCAA

Troy Trojans
14 :  31
James Madison Dukes

Nov 29, 2025 - NCAA

James Madison Dukes
59 :  10
Coastal Carolina Chanticleers

Nov 22, 2025 - NCAA

Washington State Cougars
20 :  24
James Madison Dukes

Nov 15, 2025 - NCAA

Appalachian State Mountaineers
10 :  58
James Madison Dukes

Nov 8, 2025 - NCAA

James Madison Dukes
35 :  23
Marshall Herd

Oct 28, 2025 - NCAA

James Madison Dukes
52 :  20
Texas State Bobcats
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Dec 5, 2025 - NCAA

Troy Trojans
14 :  31
James Madison Dukes

Nov 22, 2025 - NCAA

Washington State Cougars
20 :  24
James Madison Dukes

Nov 15, 2025 - NCAA

Appalachian State Mountaineers
10 :  58
James Madison Dukes

Oct 18, 2025 - NCAA

Old Dominion Monarchs
27 :  63
James Madison Dukes

Oct 11, 2025 - NCAA

Louisiana-Lafayette Ragin Cajuns
14 :  24
James Madison Dukes

Sep 27, 2025 - NCAA

Georgia Southern Eagles
10 :  35
James Madison Dukes
L W W W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Nov 29, 2025 - NCAA

James Madison Dukes
59 :  10
Coastal Carolina Chanticleers

Nov 8, 2025 - NCAA

James Madison Dukes
35 :  23
Marshall Herd

Oct 28, 2025 - NCAA

James Madison Dukes
52 :  20
Texas State Bobcats

Oct 4, 2025 - NCAA

James Madison Dukes
14 :  7
Georgia State Panthers

Sep 20, 2025 - NCAA

James Madison Dukes
31 :  13
Liberty Flames

Sep 5, 2025 - NCAA

James Madison Dukes
14 :  28
Louisville Cardinals
Oregon Ducks
Oregon Ducks Latest matches
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Nov 29, 2025 - NCAA

Oregon Ducks
26 :  14
Washington Huskies

Nov 22, 2025 - NCAA

USC Trojans
27 :  42
Oregon Ducks

Nov 14, 2025 - NCAA

Minnesota Golden Gophers
13 :  42
Oregon Ducks

Nov 8, 2025 - NCAA

Oregon Ducks
18 :  16
Iowa Hawkeyes

Oct 25, 2025 - NCAA

Wisconsin Badgers
7 :  21
Oregon Ducks

Oct 18, 2025 - NCAA

Oregon Ducks
56 :  10
Rutgers Scarlet Knights
W W L W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Nov 22, 2025 - NCAA

USC Trojans
27 :  42
Oregon Ducks

Nov 14, 2025 - NCAA

Minnesota Golden Gophers
13 :  42
Oregon Ducks

Oct 25, 2025 - NCAA

Wisconsin Badgers
7 :  21
Oregon Ducks

Oct 11, 2025 - NCAA

Indiana Hoosiers
30 :  20
Oregon Ducks

Sep 20, 2025 - NCAA

Oregon State Beavers
7 :  41
Oregon Ducks

Sep 6, 2025 - NCAA

Oklahoma State Cowboys
3 :  69
Oregon Ducks
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Nov 29, 2025 - NCAA

Oregon Ducks
26 :  14
Washington Huskies

Nov 8, 2025 - NCAA

Oregon Ducks
18 :  16
Iowa Hawkeyes

Oct 18, 2025 - NCAA

Oregon Ducks
56 :  10
Rutgers Scarlet Knights

Sep 27, 2025 - NCAA

Oregon Ducks
30 :  24
Penn State Nittany Lions

Sep 13, 2025 - NCAA

Oregon Ducks
34 :  14
Northwestern Wildcats

Sep 28, 2024 - NCAA

Oregon Ducks
34 :  13
UCLA Bruins

James Madison Dukes - Oregon Ducks Key Points

  1. James Madison is averaging 37.3 points per game
  2. James Madison is allowing 15.8 points per game
  3. Oregon is averaging 38.1 points per game
  4. Oregon is allowing 14.8 points per game

Our James Madison Dukes vs Oregon Ducks Prediction

This matchup is the most lopsided in the first round of the College Football Playoffs as Oregon is more than a three-touchdown favorite. As big as this spread is, James Madison looks to be a decent betting option. Admittedly, the Ducks have won the majority of their games by a wide margin this season. They have playmakers all over the field, and their defense is allowing just 14.8 points per game. 

That being said, James Madison has been extremely efficient offensively, especially running the ball, as they average 245.8 rushing yards per game. The Dukes are also very good defensively, allowing just 15.8 points per game. 

There is the fact that James Madison has not faced an opponent this season that compares to Oregon. However, with their ability to control the time of possession, our James Madison Dukes vs Oregon Ducks prediction is: James Madison Dukes +21.5 Alternate Spread.

Prediction:

 

James Madison Dukes +21.5 Alternate Spread

-131
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.

James Madison Dukes vs Oregon Ducks Picks