Inter Milan vs Shakhtar Donetsk Prediction & Picks - Champions League

Europe - Champions League

Inter Milan
10/21/26 15:00
Shakhtar Donetsk

Prediction:

 

Under 2.5 goals

+265
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 by Sarah Lou Jones | in Champions League Picks

Inter Milan will be hoping to pick up their first UEFA Champions League win of the season when they welcome Shakhtar Donetsk to the San Siro. Inter have lost their opening two games, firstly away at Real Madrid and then a surprising 3-2 defeat at home to Club Brugge. They need to start picking up UCL points soon, though they might find it tough against a Shakhtar side who are unbeaten in this season's Champions League. Hirnyky drew their opening UCL game away at PSV, before beating AEK Athens at home last time out.

While they may be struggling in the Champions League, I Nerazzuri are in great form in their domestic league. They're unbeaten in Serie A winning six and drawing one of their seven league games so far. As far Shakhtar, they're in fine domestic form too, winning eight of their nine league games. They have also proven to be excellent defensively, conceding just two goals across their last six games.

While Inter are clear favorites to win this game, it won't be easy. With Shakhtar excelling so far in this season's UCL, the Italian side could find this a tough game. Whatever the result, we don't think they'll be many goals in it, despite Inter's recent scorelines. For our prediction, we're looking at under 2.5 goals. 

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Inter Milan vs Shakhtar Donetsk Form

Table

Teams Pts P W D L GD
11 Shakhtar Donetsk
4 2 1 1 0 +2
29 Inter Milan
0 2 0 0 2 -2

Inter Milan and Shakhtar Donetsk Latest Matches

Inter Milan
Inter Milan Latest matches
L W D W L W
Victories

3/6 (50%)

Draw

1/6 (17%)

Defeats

2/6 (33%)

Average stats (Last 6 matchs)

4.83 Total goals
83% BTTS
2.83 Goals scored
2 Goals conceded
100% Over 2.5
0% Under 2.5

Oct 17, 2026 - Serie A

Bologna
1 :  3
Inter Milan

Oct 13, 2026 - Champions League

Inter Milan
3 :  4
Club Brugge

Oct 10, 2026 - Serie A

Inter Milan
3 :  0
Parma

Sep 19, 2026 - Serie A

Roma
2 :  2
Inter Milan

Sep 14, 2026 - Serie A

Inter Milan
5 :  3
Udinese

Sep 8, 2026 - Champions League

Real Madrid
2 :  1
Inter Milan
W W W W W L
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

4.83 Total goals
67% BTTS
3.17 Goals scored
1.67 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 13, 2026 - Champions League

Inter Milan
3 :  4
Club Brugge

Oct 10, 2026 - Serie A

Inter Milan
3 :  0
Parma

Sep 14, 2026 - Serie A

Inter Milan
5 :  3
Udinese

Sep 5, 2026 - Serie A

Inter Milan
3 :  2
Napoli

Aug 22, 2026 - Serie A

Inter Milan
4 :  1
Monza

Aug 15, 2026 - Clubs Friendlies

Inter Milan
1 :  0
Betis
D W W L D W
Victories

3/6 (50%)

Draw

2/6 (33%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

2.83 Total goals
83% BTTS
1.67 Goals scored
1.17 Goals conceded
67% Over 2.5
33% Under 2.5

Oct 17, 2026 - Serie A

Bologna
1 :  3
Inter Milan

Sep 19, 2026 - Serie A

Roma
2 :  2
Inter Milan

Sep 8, 2026 - Champions League

Real Madrid
2 :  1
Inter Milan

Aug 30, 2026 - Serie A

Cagliari
0 :  1
Inter Milan

Aug 8, 2026 - Clubs Friendlies

Juventus
1 :  2
Inter Milan

Aug 5, 2026 - Clubs Friendlies

AC Milan
1 :  1
Inter Milan
Shakhtar Donetsk
Shakhtar Donetsk Latest matches
W W W W W W
Victories

6/6 (100%)

Draw

0/6 (0%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

3 Total goals
33% BTTS
2.67 Goals scored
0.33 Goals conceded
83% Over 2.5
17% Under 2.5

Oct 17, 2026 - Ukrainian Premier League

Shakhtar Donetsk
2 :  1
Kolos Kovalivka

Oct 14, 2026 - Champions League

Shakhtar Donetsk
3 :  1
AEK Athens

Oct 9, 2026 - Ukrainian Premier League

Veres Rivne
0 :  3
Shakhtar Donetsk

Sep 20, 2026 - Ukrainian Premier League

Shakhtar Donetsk
3 :  0
LNZ Cherkasy

Sep 17, 2026 - Ukraine Cup

SK Vilkhivtsi Zakarpattya
0 :  3
Shakhtar Donetsk

Sep 14, 2026 - Ukrainian Premier League

Shakhtar Donetsk
2 :  0
FC Chernomorets Odessa
W L W W W W
Victories

5/6 (83%)

Draw

0/6 (0%)

Defeats

1/6 (17%)

Average stats (Last 6 matchs)

3.33 Total goals
50% BTTS
2.5 Goals scored
0.83 Goals conceded
67% Over 2.5
33% Under 2.5

Oct 17, 2026 - Ukrainian Premier League

Shakhtar Donetsk
2 :  1
Kolos Kovalivka

Oct 14, 2026 - Champions League

Shakhtar Donetsk
3 :  1
AEK Athens

Sep 20, 2026 - Ukrainian Premier League

Shakhtar Donetsk
3 :  0
LNZ Cherkasy

Sep 14, 2026 - Ukrainian Premier League

Shakhtar Donetsk
2 :  0
FC Chernomorets Odessa

Aug 29, 2026 - Ukrainian Premier League

Shakhtar Donetsk
0 :  2
FC Polissya Zhytomyr

Aug 3, 2026 - Ukrainian Premier League

Shakhtar Donetsk
5 :  1
Kudrivka Irpin
W W W D W W
Victories

5/6 (83%)

Draw

1/6 (17%)

Defeats

0/6 (0%)

Average stats (Last 6 matchs)

2.33 Total goals
33% BTTS
2 Goals scored
0.33 Goals conceded
50% Over 2.5
50% Under 2.5

Oct 9, 2026 - Ukrainian Premier League

Veres Rivne
0 :  3
Shakhtar Donetsk

Sep 17, 2026 - Ukraine Cup

SK Vilkhivtsi Zakarpattya
0 :  3
Shakhtar Donetsk

Sep 10, 2026 - Champions League

PSV Eindhoven
1 :  1
Shakhtar Donetsk

Sep 5, 2026 - Ukrainian Premier League

Karpaty Lviv
1 :  2
Shakhtar Donetsk

Aug 16, 2026 - Ukrainian Premier League

FC Kharkiv
0 :  1
Shakhtar Donetsk

Aug 9, 2026 - Ukrainian Premier League

FC Epitsentr Kamianets-Podilskyi
0 :  2
Shakhtar Donetsk

Inter Milan against Shakhtar Donetsk : Head to Head (H2H)

Inter Milan

40 %

Draw

60 %

Shakhtar Donetsk

0 %

Average stats (last H2H results)

1.4
Total goals
0%
BTTS
1.4
Goals scored
0
Goals conceded
20%
Over 2.5
80%
Under 2.5

Nov 24, 2021 - Champions League

Inter Milan
2 :  0
Shakhtar Donetsk

Sep 28, 2021 - Champions League

Shakhtar Donetsk
0 :  0
Inter Milan

Dec 9, 2020 - Champions League

Inter Milan
0 :  0
Shakhtar Donetsk

Oct 27, 2020 - Champions League

Shakhtar Donetsk
0 :  0
Inter Milan

Aug 17, 2020 - Europa League

Inter Milan
5 :  0
Shakhtar Donetsk
Inter Milan vs Shakhtar Donetsk Picks

Players list

Inter Milan
Inter Milan
Goalkeeper

J. Martinez

Defender

Y. Bisseck

M. Akanji

A. Bastoni

F. Dimarco

Midfielder

N. Barella

P. Zielinski

P. Sucic

Forward

Luis Henrique

M. Thuram

F. Esposito

Shakhtar Donetsk
Shakhtar Donetsk
Goalkeeper

D. Riznyk

Defender

Tobias

V. Bondar

A. Matturro

O. Karavaev

Midfielder

D. Kryskiv

Y. Nazaryna

Isaque

Forward

Bruninho

Luca Meirelles

P. Obah

Substitutes

Inter Milan
Inter Milan
Goalkeeper

R. Di Gennaro

I. Provedel

Defender

L. Bovio

C. Augusto

D. Spence

A. Stankovic

Midfielder

H. Calhanoglu

H. Mkhitaryan

A. Diouf

Forward

A. Bonny

M. Mosconi

Shakhtar Donetsk
Shakhtar Donetsk
Goalkeeper

D. Tvardovskyi

Defender

Pedro Henrique

M. Matvienko

Midfielder

O. Ocheretko

M. Gomes

Gabriel Carvalho

G. Mendoza

V. Tsukanov

Forward

L. Traore

Alisson

K. Elias

Pedrinho

Missing players

Inter Milan
Inter Milan
Defender

B. Pavard

Midfielder

C. Jones

Forward

L. Martinez

Shakhtar Donetsk
Shakhtar Donetsk
Goalkeeper

K. Fesiun

Defender

Irakli Azarov

A. Ghram

Forward

Eguinaldo

Most goals and assists

CD Huachipato Inter Milan
CD Huachipato Shakhtar Donetsk
Top Goalscorer
Argentina L. Martinez (2 Goals)
Top Goalscorer
Venezuela G. Mendoza (2 Goals)
Best assists
Argentina L. Martinez (1 Assists) , 
Serbia A. Stankovic (1 Assists) , 
Italy F. Dimarco (1 Assists)
Best assists
Brazil Isaque (2 Assists)

Inter Milan and Shakhtar Donetsk Stats in Champions League

Inter Milan
Inter Milan
Shakhtar Donetsk
Shakhtar Donetsk
0%
Wins
50%
100%
Losses
0%
0%
Draws
50%
5
Average goals per match
3
2
Goals scored per match
2
3
Goals conceded per match
1
0%
Under 2.5 goals
50%
100%
Over 2.5 goals
50%
0%
No goals conceded
0%
100%
Both score
100%

Inter Milan - Shakhtar Donetsk Key Points

  1. Shakhtar have only conceded twice in their last six
  2. Three of the last four head to heads have ended goalless
  3. Inter are missing key player Lautaro Martinez
  4. Inter have struggled so far in UCL
Up to $200 to bet on Inter Milan - Shakhtar Donetsk! 

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Our Inter Milan vs Shakhtar Donetsk Prediction

Despite Inter being the favorites to win, we think Shakhtar have a better chance of getting something from this game than the sportsbooks are predicting. Whatever the result, we think Inter will find it tough to break down this Shakhtar defence.

Our prediction for Inter Milan vs Shakhtar Donetsk is: Under 2.5 Goals

Prediction:

 

Under 2.5 goals

+265
$200 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.