Kansas City Chiefs vs Indianapolis Colts Prediction & Picks - NFL
USA - NFL
New customers only | Commercial content | 21+ age limit | T&Cs apply
by Matt Lowrimore | in NFL Picks
One of the important games on the Week 12 NFL Sunday slate will see the Kansas City Chiefs take on the Indianapolis Colts. Let’s take a look at the match statistics and predictions for this game between the Chiefs and the Colts.
Indianapolis enters this game with a record of 8-2, having most recently beaten the Atlanta Falcons in Week 10 by a score of 31-25. The Colts’ offense had a total of 519 yards, while its defense allowed 290 yards. Quarterback Daniel Jones threw for 255 yards, one touchdown, and one interception, while running back Jonathan Taylor led the team in rushing with 244 yards and three touchdowns.
As for Kansas City, they enter this game with a record of 5-5, having most recently lost to the Denver Broncos in Week 11 by a score of 22-19. Kansas City’s offense had a total of 311 yards, while its defense allowed 342 yards. Quarterback Patrick Mahomes threw for 276 yards, one touchdown, and one interception, while running back Kareem Hunt led the team in rushing with 59 yards and one touchdown.
Limited Offer. Currently at DraftKings
Kansas City Chiefs vs Indianapolis Colts Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
20
|
0.471 | 17 | 8 | 9 |
|
24
|
0.353 | 17 | 6 | 11 |
Kansas City Chiefs and Indianapolis Colts Latest Matches
3/6 (50%)
3/6 (50%)
Nov 16, 2025 - NFL
Nov 2, 2025 - NFL
Oct 27, 2025 - NFL
Oct 19, 2025 - NFL
Oct 12, 2025 - NFL
Oct 6, 2025 - NFL
5/6 (83%)
1/6 (17%)
Oct 27, 2025 - NFL
Oct 19, 2025 - NFL
Oct 12, 2025 - NFL
Sep 28, 2025 - NFL
Sep 14, 2025 - NFL
Jan 26, 2025 - NFL
1/6 (17%)
5/6 (83%)
Nov 16, 2025 - NFL
Nov 2, 2025 - NFL
Oct 6, 2025 - NFL
Sep 21, 2025 - NFL
Sep 5, 2025 - NFL
Feb 9, 2025 - NFL
5/6 (83%)
1/6 (17%)
Nov 9, 2025 - NFL
Nov 2, 2025 - NFL
Oct 26, 2025 - NFL
Oct 19, 2025 - NFL
Oct 12, 2025 - NFL
Oct 5, 2025 - NFL
6/6 (100%)
0/6 (0%)
Nov 9, 2025 - NFL
Oct 26, 2025 - NFL
Oct 12, 2025 - NFL
Oct 5, 2025 - NFL
Sep 14, 2025 - NFL
Sep 7, 2025 - NFL
2/6 (33%)
4/6 (67%)
Nov 2, 2025 - NFL
Oct 19, 2025 - NFL
Sep 28, 2025 - NFL
Sep 21, 2025 - NFL
Dec 29, 2024 - NFL
Dec 15, 2024 - NFL
Kansas City Chiefs - Indianapolis Colts Key Points
- The Colts are averaging 32.1 points per game
- The Colts are allowing 20.6 points per game
- The Chiefs are averaging 25.4 points per game
- The Chiefs are allowing 18.1 points per game
Limited Offer. Currently at DraftKings
Our Kansas City Chiefs vs Indianapolis Colts Prediction
Despite the Chiefs being in danger of making the playoffs, they are the favorites in this game against the red-hot Colts. Indianapolis is coming off a bye week after playing in Germany, where they beat the Atlanta Falcons in overtime and had an MVP-level performance from Jonathan Taylor.
Of course, this game is being played in Kansas City, which you think would give the Chiefs an advantage. However, teams seem to have figured out the Chiefs this season, and as a result, playing in Arrowhead is not as brutal as it normally would be.
Kansas City still has a solid offense and an excellent defense; however, the Colts are even better offensively and are just as good defensively. For that reason, our Kansas City Chiefs vs Indianapolis Colts prediction is: Indianapolis Colts +3.5.All tips are fully researched and given in good faith, but profits cannot be guaranteed.
