USA - NCAA
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by Travis Pulver in NCAA Picks
The No. 2 Indiana Hoosiers will go for the program’s first win in Happy Valley when they take on the struggling Penn State Nittany Lions at Beaver Stadium in University Park, PA, Saturday afternoon. Kickoff for this Big Ten contest is scheduled for 12 p.m. EST. Fans can follow the game on Fox.
Expectations were high for the Nittany Lions coming into the season, and it looked like they might live up to them as they got off to a 3-0 start. But then things quickly fell apart as the team lost five in a row to start Big Ten play, losing their starting quarterback to a season-ending injury and head coach James Franklin (fired). As for Indiana, the journey has been the exact opposite, as they have dominated the competition on both sides of the ball. The Hoosiers have been flying high all season en route to a 9-0 start, becoming the No. 2 team in the first CFP poll. Quarterback Fernando Mendoza has developed into a Heisman front-runner and the popular choice to go No. 1 in the next NFL draft. Should Indiana meet Ohio State in the Big Ten title game as expected, it could be the most anticipated game of the season.
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Indiana Hoosiers vs Penn State Nittany Lions Form
Table
| Teams | % | P | W | D | L |
|---|---|---|---|---|---|
|
1
|
1 | 6 | 6 | 0 | 0 |
|
15
|
0 | 5 | 0 | 0 | 5 |
Indiana Hoosiers and Penn State Nittany Lions Latest Matches
6/6 (100%)
0/6 (0%)
0/6 (0%)
Nov 1, 2025 - NCAA
Oct 25, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 11, 2025 - NCAA
Sep 27, 2025 - NCAA
Sep 20, 2025 - NCAA
6/6 (100%)
0/6 (0%)
0/6 (0%)
Oct 25, 2025 - NCAA
Oct 18, 2025 - NCAA
Sep 20, 2025 - NCAA
Sep 12, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
3/5 (60%)
0/5 (0%)
2/5 (40%)
Nov 1, 2025 - NCAA
Oct 11, 2025 - NCAA
Sep 27, 2025 - NCAA
Dec 20, 2024 - NCAA
Nov 23, 2024 - NCAA
1/6 (17%)
0/6 (0%)
5/6 (83%)
Nov 1, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 11, 2025 - NCAA
Oct 4, 2025 - NCAA
Sep 27, 2025 - NCAA
Sep 13, 2025 - NCAA
3/6 (50%)
0/6 (0%)
3/6 (50%)
Oct 11, 2025 - NCAA
Sep 27, 2025 - NCAA
Sep 13, 2025 - NCAA
Sep 6, 2025 - NCAA
Aug 30, 2025 - NCAA
Jan 9, 2025 - NCAA
2/6 (33%)
0/6 (0%)
4/6 (67%)
Nov 1, 2025 - NCAA
Oct 18, 2025 - NCAA
Oct 4, 2025 - NCAA
Dec 31, 2024 - NCAA
Dec 7, 2024 - NCAA
Nov 23, 2024 - NCAA
Indiana Hoosiers - Penn State Nittany Lions Key Points
- Penn State has dominated the all-time series vs. Indiana going 25-2; both IU wins were at home.
- Indiana is 6-3 ATS while Penn State is 1-7.
- The OVER is 6-2 for Penn State and 6-3 for Indiana.
- Betting Public: 66% of spread tickets and 63% of the handle are on the Hoosiers (-14.5).
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Our Indiana Hoosiers vs Penn State Nittany Lions Prediction
Penn State is struggling hard this season, but the Nittany Lions still have a pretty solid defense. However, while it may slow Indiana down in the first quarter (half at the most), there is no way the Nittany Lions keep up with the Hoosiers. Indiana has the No. 1 scoring offense in the country and the No. 3 scoring defense. Penn State’s defense will eventually wear down like everyone else.
Our Indiana vs. Penn State Pick: Indiana -14.5
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