San Diego Padres vs Houston Astros Prediction & Picks - MLB

USA - MLB

San Diego Padres
8/9/26 20:20
Houston Astros

Prediction:

 

OVER 8.5

-115
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 by Travis Pulver in MLB Picks

The San Diego Padres (61-57, 33-26 Home) will host the Houston Astros (6-58, 30-29 Away) in the series finale of their three-game weekend series today. The action is set to get underway at Petco Park in San Diego, CA, at 8:20 p.m. EST on NBC.

Houston entered the series fresh off a loss to Toronto at home in extra innings on Thursday and rebounded with a 6-3 win over the Padres Friday night. But it was San Diego’s turn to rebound yesterday as they took the W in a close 3-2 contest.

Randy Vasquez is scheduled to start for the Padres. Vasquez is 7-6 in 22 appearances (18 starts) with a 4.19 ERA and a 1.42 WHIP. Teams have hit .285 against him. He has not had his best stuff at home, where he is 3-4 in 10 appearances (eight starts) with a 4.91 ERA and a .299 OBA.

As for Houston, the Astros are scheduled to go with Cristian Javier to start the day. Javier is 1-2 this season in nine appearances (five starts). He has gone 1-1 on the road in five appearances (three starts) with a 6.59 ERA and a .298 OBA.


 

San Diego Padres vs Houston Astros Form

Table

Teams Pts P W L
11 San Diego Padres
0.517 118 61 57
12 Houston Astros
0.508 118 60 58

San Diego Padres and Houston Astros Latest Matches

San Diego Padres
San Diego Padres Latest matches
L W L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 8, 2026 - MLB

San Diego Padres
3 :  2
Houston Astros

Aug 7, 2026 - MLB

San Diego Padres
3 :  6
Houston Astros

Aug 6, 2026 - MLB

Arizona Diamondbacks
1 :  5
San Diego Padres

Aug 5, 2026 - MLB

Arizona Diamondbacks
10 :  4
San Diego Padres

Aug 4, 2026 - MLB

Arizona Diamondbacks
4 :  9
San Diego Padres

Aug 3, 2026 - MLB

Arizona Diamondbacks
5 :  1
San Diego Padres
L W W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 8, 2026 - MLB

San Diego Padres
3 :  2
Houston Astros

Aug 7, 2026 - MLB

San Diego Padres
3 :  6
Houston Astros

Aug 2, 2026 - MLB

San Diego Padres
5 :  4
San Francisco Giants

Aug 1, 2026 - MLB

San Diego Padres
6 :  5
San Francisco Giants

Jul 31, 2026 - MLB

San Diego Padres
7 :  0
San Francisco Giants

Jul 30, 2026 - MLB

San Diego Padres
1 :  4
San Francisco Giants
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 6, 2026 - MLB

Arizona Diamondbacks
1 :  5
San Diego Padres

Aug 5, 2026 - MLB

Arizona Diamondbacks
10 :  4
San Diego Padres

Aug 4, 2026 - MLB

Arizona Diamondbacks
4 :  9
San Diego Padres

Aug 3, 2026 - MLB

Arizona Diamondbacks
5 :  1
San Diego Padres

Jul 26, 2026 - MLB

Miami Marlins
3 :  5
San Diego Padres

Jul 25, 2026 - MLB

Miami Marlins
2 :  7
San Diego Padres
Houston Astros
Houston Astros Latest matches
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Aug 8, 2026 - MLB

San Diego Padres
3 :  2
Houston Astros

Aug 7, 2026 - MLB

San Diego Padres
3 :  6
Houston Astros

Aug 5, 2026 - MLB

Houston Astros
4 :  5
Toronto Blue Jays

Aug 4, 2026 - MLB

Houston Astros
7 :  2
Toronto Blue Jays

Aug 3, 2026 - MLB

Houston Astros
1 :  3
Toronto Blue Jays

Aug 2, 2026 - MLB

Houston Astros
7 :  3
Texas Rangers
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 5, 2026 - MLB

Houston Astros
4 :  5
Toronto Blue Jays

Aug 4, 2026 - MLB

Houston Astros
7 :  2
Toronto Blue Jays

Aug 3, 2026 - MLB

Houston Astros
1 :  3
Toronto Blue Jays

Aug 2, 2026 - MLB

Houston Astros
7 :  3
Texas Rangers

Aug 1, 2026 - MLB

Houston Astros
5 :  4
Texas Rangers

Jul 31, 2026 - MLB

Houston Astros
11 :  2
Texas Rangers
L W W W W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 8, 2026 - MLB

San Diego Padres
3 :  2
Houston Astros

Aug 7, 2026 - MLB

San Diego Padres
3 :  6
Houston Astros

Jul 29, 2026 - MLB

Los Angeles Angels
4 :  7
Houston Astros

Jul 28, 2026 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Jul 27, 2026 - MLB

Los Angeles Angels
4 :  6
Houston Astros

Jul 26, 2026 - MLB

Chicago White Sox
12 :  3
Houston Astros

San Diego Padres against Houston Astros : Head to Head (H2H)

San Diego Padres

50 %

Houston Astros

50 %

Aug 8, 2026 - MLB

San Diego Padres
3 :  2
Houston Astros

Aug 7, 2026 - MLB

San Diego Padres
3 :  6
Houston Astros

Apr 20, 2025 - MLB

Houston Astros
2 :  3
San Diego Padres

Apr 19, 2025 - MLB

Houston Astros
3 :  2
San Diego Padres

Apr 18, 2025 - MLB

Houston Astros
6 :  4
San Diego Padres

Sep 18, 2024 - MLB

San Diego Padres
4 :  0
Houston Astros
San Diego Padres vs Houston Astros Picks

San Diego Padres - Houston Astros Key Points

  1. Houston leads the all-time series vs. San Diego, 323-298.
  2. San Diego is 30-29 ATS (run line) at home; Houston is 31-28 ATS (run line) on the road.
  3. The OVER is 26-32-1 for San Diego at home and 30-26-3 for the Astros on the road.
  4. Betting Public: 55% of total tickets and 58% of the handle are on the OVER.

Our San Diego Padres vs Houston Astros Prediction

There hasn’t been a ton of offense in this series, but I expect that to change today, with two starting pitchers and teams hitting close to .300 against this season. I might give Houston a slight edge in this game since the Astros have hit .287 over the last week, but the Padres have hit .245 and generated more runs (30-27), albeit with an additional game (seven to six). But Vasquez has been better than Javier, so I don’t know that it is much of an edge at all. It is hard to say who will win this game, but it will more than likely be a high-scoring contest.

Our Houston vs. San Diego Pick: Over 8.5

Prediction:

 

OVER 8.5

-115
$1000 offered for betting!

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