San Diego Padres vs Houston Astros Prediction & Picks - MLB

USA - MLB

San Diego Padres
8/7/26 21:40
Houston Astros

Prediction:

 

Over 8

-115
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 by Bill Christy | in MLB Picks

The Houston Astros begin a road trip to the West Coast tonight. They will begin with a 3-game series against the San Diego Padres before taking on the San Francisco Giants early next week.

The Astros are coming off losing 2 of their 3 games in their previous series against the Toronto Blue Jays. This will be the 1st time they face the Padres on the season and are hoping to hold onto their 1.5 gam lead on the Rangers for the top spot in the AL West. Things will not be easy tonight as they are starting Ronel Blanco, who is just 0-1 and has a 7.36 ERA in his 3 starts on the season. Luckily, the Astros are in the top 10 in the league in runs scored, so run support should be available for him.

The Padres are coming off a 2-2 split in their series with the Arizona Diamondbacks. Over those 4 games, they combined to average 9.75 runs per game. That number only grows when looking back at their previous games this month. While their lineup is not the most imposing, they are being treated to Ronel Blanco as the opposing pitcher, who they should be able to get to early.

San Diego Padres vs Houston Astros Form

Table

Teams Pts P W L
10 San Diego Padres
0.521 119 62 57
12 Houston Astros
0.504 119 60 59

San Diego Padres and Houston Astros Latest Matches

San Diego Padres
San Diego Padres Latest matches
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 6, 2026 - MLB

Arizona Diamondbacks
1 :  5
San Diego Padres

Aug 5, 2026 - MLB

Arizona Diamondbacks
10 :  4
San Diego Padres

Aug 4, 2026 - MLB

Arizona Diamondbacks
4 :  9
San Diego Padres

Aug 3, 2026 - MLB

Arizona Diamondbacks
5 :  1
San Diego Padres

Aug 2, 2026 - MLB

San Diego Padres
5 :  4
San Francisco Giants

Aug 1, 2026 - MLB

San Diego Padres
6 :  5
San Francisco Giants
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Aug 2, 2026 - MLB

San Diego Padres
5 :  4
San Francisco Giants

Aug 1, 2026 - MLB

San Diego Padres
6 :  5
San Francisco Giants

Jul 31, 2026 - MLB

San Diego Padres
7 :  0
San Francisco Giants

Jul 30, 2026 - MLB

San Diego Padres
1 :  4
San Francisco Giants

Jul 29, 2026 - MLB

San Diego Padres
3 :  1
Colorado Rockies

Jul 28, 2026 - MLB

San Diego Padres
8 :  7
Colorado Rockies
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 6, 2026 - MLB

Arizona Diamondbacks
1 :  5
San Diego Padres

Aug 5, 2026 - MLB

Arizona Diamondbacks
10 :  4
San Diego Padres

Aug 4, 2026 - MLB

Arizona Diamondbacks
4 :  9
San Diego Padres

Aug 3, 2026 - MLB

Arizona Diamondbacks
5 :  1
San Diego Padres

Jul 26, 2026 - MLB

Miami Marlins
3 :  5
San Diego Padres

Jul 25, 2026 - MLB

Miami Marlins
2 :  7
San Diego Padres
Houston Astros
Houston Astros Latest matches
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 5, 2026 - MLB

Houston Astros
4 :  5
Toronto Blue Jays

Aug 4, 2026 - MLB

Houston Astros
7 :  2
Toronto Blue Jays

Aug 3, 2026 - MLB

Houston Astros
1 :  3
Toronto Blue Jays

Aug 2, 2026 - MLB

Houston Astros
7 :  3
Texas Rangers

Aug 1, 2026 - MLB

Houston Astros
5 :  4
Texas Rangers

Jul 31, 2026 - MLB

Houston Astros
11 :  2
Texas Rangers
W W W L W L
Victories

4/6 (67%)

Defeats

2/6 (33%)

Aug 5, 2026 - MLB

Houston Astros
4 :  5
Toronto Blue Jays

Aug 4, 2026 - MLB

Houston Astros
7 :  2
Toronto Blue Jays

Aug 3, 2026 - MLB

Houston Astros
1 :  3
Toronto Blue Jays

Aug 2, 2026 - MLB

Houston Astros
7 :  3
Texas Rangers

Aug 1, 2026 - MLB

Houston Astros
5 :  4
Texas Rangers

Jul 31, 2026 - MLB

Houston Astros
11 :  2
Texas Rangers
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jul 29, 2026 - MLB

Los Angeles Angels
4 :  7
Houston Astros

Jul 28, 2026 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Jul 27, 2026 - MLB

Los Angeles Angels
4 :  6
Houston Astros

Jul 26, 2026 - MLB

Chicago White Sox
12 :  3
Houston Astros

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

San Diego Padres against Houston Astros : Head to Head (H2H)

San Diego Padres

50 %

Houston Astros

50 %

Apr 19, 2025 - MLB

Houston Astros
3 :  2
San Diego Padres

Apr 18, 2025 - MLB

Houston Astros
6 :  4
San Diego Padres

Sep 18, 2024 - MLB

San Diego Padres
4 :  0
Houston Astros

Sep 17, 2024 - MLB

San Diego Padres
3 :  4
Houston Astros

Sep 16, 2024 - MLB

San Diego Padres
3 :  1
Houston Astros

Sep 4, 2021 - MLB

San Diego Padres
10 :  2
Houston Astros
San Diego Padres vs Houston Astros Picks

San Diego Padres - Houston Astros Key Points

  1. Over is 3-0 in Blanco’s starts.
  2. Over is 2-1 in Ray’s last 3 starts.
  3. Over is 4-0 in Padres last 4 home games vs. a team with a losing road record.
  4. Over is 4-0 in Astros last 4 games as a road favorite.

Our San Diego Padres vs Houston Astros Prediction

San Diego has been playing to the over in the majority of their recent games. That, combined with Blanco’s consistent struggles this year, leads us to believe the Padres could do the bulk of the work in getting this total over the line. Houston will play their part as well. Robbie Ray will make his 1st start with his new club and will not have an easy time against the Astros' offense.

Our prediction for San Diego Padres vs Houston Astros: Over 8

Prediction:

 

Over 8

-115
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.