Philadelphia Phillies vs Houston Astros Prediction & Picks - MLB

USA - MLB

Philadelphia Phillies
9/9/26 18:40
Houston Astros

Prediction:

 

Under 8 Total Runs

-105
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 by Matt Lowrimore in MLB Picks

A massive 15-game MLB slate is scheduled for Wednesday, one of which will include an interleague matchup between the Philadelphia Phillies and the Houston Astros. Let’s take a look at the match statistics and predictions for this game between the Phillies and the Astros.

Houston enters this game a handful of games above .500, yet is still currently in first place in the American League West Division. Set to start this game for the Astros is Hunter Brown, who has an ERA of 3.31. To go along with his solid numbers overall, Brown has been much more reliable on the road, a trend that should continue against the Phillies.

As for Philadelphia, they enter this game with one of the better records in the league; however, they are currently in second place in the National League East Division. Starting this game for the Phillies will be Cristopher Sanchez, who has an ERA of 2.58. Sanchez rarely gives up runs when pitching at home, suggesting that this game looks likely to be a pitchers’ duel.

Philadelphia Phillies vs Houston Astros Form

Table

Teams Pts P W L
6 Philadelphia Phillies
0.559 145 81 64
12 Houston Astros
0.51 145 74 71

Philadelphia Phillies and Houston Astros Latest Matches

Philadelphia Phillies
Philadelphia Phillies Latest matches
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Sep 8, 2026 - MLB

Philadelphia Phillies
5 :  6
Houston Astros

Sep 7, 2026 - MLB

Philadelphia Phillies
1 :  0
Atlanta Braves

Sep 6, 2026 - MLB

Philadelphia Phillies
4 :  5
Atlanta Braves

Sep 5, 2026 - MLB

Philadelphia Phillies
4 :  2
Atlanta Braves

Sep 4, 2026 - MLB

Philadelphia Phillies
2 :  5
Atlanta Braves

Sep 2, 2026 - MLB

Arizona Diamondbacks
1 :  0
Philadelphia Phillies
W L W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 8, 2026 - MLB

Philadelphia Phillies
5 :  6
Houston Astros

Sep 7, 2026 - MLB

Philadelphia Phillies
1 :  0
Atlanta Braves

Sep 6, 2026 - MLB

Philadelphia Phillies
4 :  5
Atlanta Braves

Sep 5, 2026 - MLB

Philadelphia Phillies
4 :  2
Atlanta Braves

Sep 4, 2026 - MLB

Philadelphia Phillies
2 :  5
Atlanta Braves

Aug 23, 2026 - MLB

Philadelphia Phillies
6 :  4
St. Louis Cardinals
W W W W W L
Victories

5/6 (83%)

Defeats

1/6 (17%)

Sep 2, 2026 - MLB

Arizona Diamondbacks
1 :  0
Philadelphia Phillies

Sep 1, 2026 - MLB

Arizona Diamondbacks
1 :  7
Philadelphia Phillies

Aug 31, 2026 - MLB

Arizona Diamondbacks
1 :  2
Philadelphia Phillies

Aug 30, 2026 - MLB

Los Angeles Angels
2 :  5
Philadelphia Phillies

Aug 29, 2026 - MLB

Los Angeles Angels
2 :  4
Philadelphia Phillies

Aug 28, 2026 - MLB

Los Angeles Angels
3 :  5
Philadelphia Phillies
Houston Astros
Houston Astros Latest matches
W W W L L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 8, 2026 - MLB

Philadelphia Phillies
5 :  6
Houston Astros

Sep 6, 2026 - MLB

Houston Astros
2 :  3
Arizona Diamondbacks

Sep 5, 2026 - MLB

Houston Astros
3 :  4
Arizona Diamondbacks

Sep 4, 2026 - MLB

Houston Astros
3 :  1
Arizona Diamondbacks

Sep 3, 2026 - MLB

Houston Astros
6 :  2
Chicago White Sox

Sep 2, 2026 - MLB

Houston Astros
2 :  0
Chicago White Sox
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Sep 6, 2026 - MLB

Houston Astros
2 :  3
Arizona Diamondbacks

Sep 5, 2026 - MLB

Houston Astros
3 :  4
Arizona Diamondbacks

Sep 4, 2026 - MLB

Houston Astros
3 :  1
Arizona Diamondbacks

Sep 3, 2026 - MLB

Houston Astros
6 :  2
Chicago White Sox

Sep 2, 2026 - MLB

Houston Astros
2 :  0
Chicago White Sox

Sep 1, 2026 - MLB

Houston Astros
1 :  5
Chicago White Sox
L W W L W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Sep 8, 2026 - MLB

Philadelphia Phillies
5 :  6
Houston Astros

Aug 30, 2026 - MLB

New York Mets
3 :  6
Houston Astros

Aug 29, 2026 - MLB

New York Mets
6 :  2
Houston Astros

Aug 28, 2026 - MLB

New York Mets
1 :  3
Houston Astros

Aug 27, 2026 - MLB

New York Yankees
1 :  5
Houston Astros

Aug 26, 2026 - MLB

New York Yankees
9 :  3
Houston Astros

Philadelphia Phillies against Houston Astros : Head to Head (H2H)

Philadelphia Phillies

17 %

Houston Astros

83 %

Sep 8, 2026 - MLB

Philadelphia Phillies
5 :  6
Houston Astros

Jun 26, 2025 - MLB

Houston Astros
2 :  1
Philadelphia Phillies

Jun 25, 2025 - MLB

Houston Astros
2 :  0
Philadelphia Phillies

Jun 24, 2025 - MLB

Houston Astros
1 :  0
Philadelphia Phillies

Aug 28, 2024 - MLB

Philadelphia Phillies
0 :  10
Houston Astros

Aug 27, 2024 - MLB

Philadelphia Phillies
5 :  0
Houston Astros
Philadelphia Phillies vs Houston Astros Picks

Philadelphia Phillies - Houston Astros Key Points

  1. Hunter Brown has an ERA of 3.31 this season
  2. Hunter Brown has an ERA of 2.67 on the road this season
  3. Cristopher Sanchez has an ERA of 2.58 this season
  4. Cristopher Sanchez has an ERA of 1.83 at home this season

Our Philadelphia Phillies vs Houston Astros Prediction

The Phillies are the heavy favorite in this game; however, the under looks to be the best betting option. This is because of the home/away splits between the two starting pitchers. Brown has made just six away starts this season, but has only allowed 11 runs (10 earned) over 33.2 innings. Sanchez, on the other hand, has made 17 home starts, in which he has allowed just 26 runs (22 earned) over 108.0 innings.

Both offenses have been able to consistently score this season, but because both starters have also consistently been elite, our Philadelphia Phillies vs Houston Astros prediction is: Under 8 Total Runs.

Prediction:

 

Under 8 Total Runs

-105
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.