Athletics vs Houston Astros Prediction & Picks - MLB
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by Matt Lowrimore | in MLB Picks
The final Saturday of the MLB regular season will consist of 13 games, one of which features an American League West matchup between the Athletics and the Houston Astros. Let’s take a look at the match statistics and predictions for this game between the Athletics and the Astros.
The Astros enter this game hovering at .500 on the season and are currently tied for first place in the American League West Division. Given this, this is a must-win game for Houston, who are desperately trying to win the division over the Texas Rangers. Set to start this game for the Astros will be Hayden Wesneski, who has an ERA of 3.50. Wesneski has struggled this season on the road, which could allow the Athletics offense to score against him early.
As for the Athletics, they enter this game with one of the worst records in the league and are currently in fourth place in the American League West Division. Further, the Athletics have long been eliminated from the playoffs. Starting this game for the Athletics will be Jack Perkins, who has an ERA of 5.90 this season. He has been especially bad when pitching at home, suggesting the Astros will be able to take full advantage.
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Athletics vs Houston Astros Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
14
|
0.5 | 162 | 81 | 81 |
|
28
|
0.395 | 162 | 64 | 98 |
Athletics and Houston Astros Latest Matches
3/6 (50%)
3/6 (50%)
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4/6 (67%)
2/6 (33%)
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0/6 (0%)
6/6 (100%)
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2/6 (33%)
4/6 (67%)
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2/6 (33%)
4/6 (67%)
Sep 20, 2026 - MLB
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2/6 (33%)
4/6 (67%)
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Athletics against Houston Astros : Head to Head (H2H)
67 %
33 %
Sep 25, 2026 - MLB
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Athletics - Houston Astros Key Points
- Hayden Wesneski has an ERA of 3.50 this season
- Hayden Wesneski has an ERA of 4.39 on the road this season
- Jack Perkins has an ERA of 5.90 this season
- Jack Perkins has an ERA of 7.05 at home this season
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Our Athletics vs Houston Astros Prediction
The Astros are the favorite in this game; however, the over looks to be the best betting option. Wesneski has made just 5 away starts this season, but has allowed 17 runs (13 earned) over 26.2 innings. Perkins, on the other hand, has made 19 home appearances (9 starts), having allowed 49 runs (47 earned) over 60.0 innings.
As bad as the Athletics have been this season, Wesneski is not a pitcher who can be trusted, especially when he is pitching on the road. Because of that, and because the Astros still have an offense that can consistently score runs, our Athletics vs. Houston Astros prediction is: Over 8.5 Total Runs.
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
