Los Angeles Angels vs Houston Astros Prediction & Picks - MLB

USA - MLB

Los Angeles Angels
6/22/25 16:07
Houston Astros

Prediction:

 

Houston ML

-110
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 by Travis Pulver | in MLB Picks

The Los Angeles Angels will go for the series win over the Astros when they host Houston in Game 3 of their weekend series today. The action is scheduled to get underway at Angel Stadium in Anaheim, CA, at 4:07 p.m. EST.

Houston edged out the Angels in Game 1 of the series on Friday, 3-2, but Los Angeles came back with a vengeance in Game 2 with a 9-1 victory in Game 2 yesterday. Jose Soriano held the Astros lineup to three hits and a run over 6 2/3 innings. Houston’s starter Brandon Walter had pitched well over his first three starts (1.53 ERA), but got lit up by the Angels, nine hits (two home runs) and seven runs over six innings. The Astros will try to get back on the right side of the scoreboard with Ryan Gusto on the mound to start the day. Gusto is 4-3 in ten starts and 16 appearances this season with a 4.31 ERA and 1.53 WHIP. But he has been much better on the road, though, where he is 1-1 in two starts and six appearances with a 2.40 ERA. 

Kyle Hendricks is getting the start for the Angels. Hendricks has a 5-6 record in 14 starts with a 4.79 ERA. He has gone 3-3 at home in six starts with a 4.04 ERA and .265 OBA.

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Los Angeles Angels vs Houston Astros Form

Table

Teams Pts P W L
12 Houston Astros
0.537 162 87 75
25 Los Angeles Angels
0.444 162 72 90

Los Angeles Angels and Houston Astros Latest Matches

Los Angeles Angels
Los Angeles Angels Latest matches
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 20, 2025 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Jun 19, 2025 - MLB

New York Yankees
7 :  3
Los Angeles Angels

Jun 18, 2025 - MLB

New York Yankees
2 :  3
Los Angeles Angels

Jun 17, 2025 - MLB

New York Yankees
0 :  4
Los Angeles Angels

Jun 16, 2025 - MLB

New York Yankees
0 :  1
Los Angeles Angels

Jun 15, 2025 - MLB

Baltimore Orioles
11 :  2
Los Angeles Angels
L L L W W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Jun 20, 2025 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Jun 10, 2025 - MLB

Los Angeles Angels
2 :  1
Athletics

Jun 6, 2025 - MLB

Los Angeles Angels
5 :  4
Seattle Mariners

May 28, 2025 - MLB

Los Angeles Angels
0 :  1
New York Yankees

May 27, 2025 - MLB

Los Angeles Angels
2 :  3
New York Yankees

May 26, 2025 - MLB

Los Angeles Angels
1 :  5
New York Yankees
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jun 19, 2025 - MLB

New York Yankees
7 :  3
Los Angeles Angels

Jun 18, 2025 - MLB

New York Yankees
2 :  3
Los Angeles Angels

Jun 17, 2025 - MLB

New York Yankees
0 :  4
Los Angeles Angels

Jun 16, 2025 - MLB

New York Yankees
0 :  1
Los Angeles Angels

Jun 15, 2025 - MLB

Baltimore Orioles
11 :  2
Los Angeles Angels

Jun 13, 2025 - MLB

Baltimore Orioles
2 :  0
Los Angeles Angels
Houston Astros
Houston Astros Latest matches
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 20, 2025 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Jun 19, 2025 - MLB

Athletics
6 :  4
Houston Astros

Jun 18, 2025 - MLB

Athletics
4 :  11
Houston Astros

Jun 16, 2025 - MLB

Athletics
3 :  1
Houston Astros

Jun 12, 2025 - MLB

Houston Astros
4 :  3
Chicago White Sox

Jun 11, 2025 - MLB

Houston Astros
10 :  2
Chicago White Sox
W W L W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jun 12, 2025 - MLB

Houston Astros
4 :  3
Chicago White Sox

Jun 11, 2025 - MLB

Houston Astros
10 :  2
Chicago White Sox

May 30, 2025 - MLB

Houston Astros
2 :  1
Tampa Bay Rays

May 29, 2025 - MLB

Houston Astros
3 :  13
Tampa Bay Rays

May 27, 2025 - MLB

Houston Astros
11 :  1
Athletics

May 25, 2025 - MLB

Houston Astros
5 :  3
Seattle Mariners
W W L W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jun 20, 2025 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Jun 19, 2025 - MLB

Athletics
6 :  4
Houston Astros

Jun 18, 2025 - MLB

Athletics
4 :  11
Houston Astros

Jun 16, 2025 - MLB

Athletics
3 :  1
Houston Astros

Jun 6, 2025 - MLB

Cleveland Guardians
2 :  4
Houston Astros

Jun 5, 2025 - MLB

Pittsburgh Pirates
2 :  8
Houston Astros

Los Angeles Angels against Houston Astros : Head to Head (H2H)

Los Angeles Angels

17 %

Houston Astros

83 %

Jun 20, 2025 - MLB

Los Angeles Angels
2 :  3
Houston Astros

Apr 13, 2025 - MLB

Houston Astros
7 :  3
Los Angeles Angels

Apr 12, 2025 - MLB

Houston Astros
1 :  4
Los Angeles Angels

Apr 11, 2025 - MLB

Houston Astros
14 :  3
Los Angeles Angels

Sep 20, 2024 - MLB

Houston Astros
9 :  7
Los Angeles Angels

Sep 19, 2024 - MLB

Houston Astros
3 :  1
Los Angeles Angels

Los Angeles Angels - Houston Astros Key Points

  1. Houston leads the all-time series vs. the Angels 133-85.
  2. The Astros won nine of 12 against the Angels in Anaheim over the last two seasons.
  3. Houston is 11-12 in games where they were favored on the road.
  4. Betting Public: 62% of moneyline tickets and 70% of the handle are on Houston.
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Our Los Angeles Angels vs Houston Astros Prediction

My first thought after looking at how both lineups have been hitting and how the starting pitchers have performed is to go with the OVER. But on closer examination, I see that while Gusto has been unimpressive at home, he has been solid on the road (2.40 ERA, .237 OBA), and he’s been even better in day games (1.59 ERA, .217 OBA). It is hard to trust how much support the lineup will provide, making the runline an unadvisable bet, but Gusto and the Astros' bullpen can win this game outright.

Our Astros vs. Angels Pick: Houston ML

Prediction:

 

Houston ML

-110
$250 offered for betting!

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Los Angeles Angels vs Houston Astros Picks