Los Angeles Angels vs Houston Astros Prediction & Picks - MLB

Prediction published on 6/20/25, 6:02 PM  by Carlos Zabala | Modified on 2/11/26 at 8:27 AM in MLB Picks

Anderson couldn't pitch against the Yankees in New York like he did in Los Angeles when he dominated them. The Angels lost 3-7 in Game 4 but won the series 3-1, three games as betting underdogs, to now have a 36-38 record. Good news for the Angels is Trout's clainet bat, who homered in the loss, as did Adell and Ward, but Trout had at least one hit in all four games of the series against the Yankees.

With this, the Angels embarked on a coast-to-coast trip across the United States and will begin a new weekend series against the Astros without a break. Early in April 2011, the Astros and Angels played their first series of the season in Houston. On that occasion, the Angels were in good form, as they are now, but were thrashed by the Astros, who won Game 1 14-3. The Halos run the risk of the same thing happening to them, as the Astros have been dominant over the Angels over the last five years, winning eight of their last ten games against each other.

Kikuchi for the Angels and Brown for the Astros are expected to be Friday's pitching duel. The Japanese pitcher has managed to lower his ERA to 3.05, but he has a problem: in 2025, his strikeout rate has dropped, and he has already walked 40.