Chicago White Sox vs Houston Astros Prediction & Picks - MLB

USA - MLB

Chicago White Sox
7/26/26 14:10
Houston Astros

Prediction:

 

Astros to win

-118
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 by Simon Day in MLB Picks

The Houston Astros will be bidding to make it six wins in a row when they take on the Chicago White Sox at Guaranteed Rate Field on Sunday evening. 

The contest is the final matchup of a three game series that Houston have thus far dominated. In game one, an astonishing eight run burst in the sixth enabled the Astros to overturn a five run deficit, whilst game two saw pitcher Hunter Brown produce one of his best displays of the season to nullify the home offense and help the Astros record a comfortable 1-4 success. 

Those victories have moved Houston to within one game of the Rangers at the top of the AL West table, whilst the White Sox are now level with the Guardians in the highly competitive AL Central.

Up to $250 to bet on Chicago White Sox - Houston Astros! 

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Chicago White Sox vs Houston Astros Form

Table

Teams Pts P W L
8 Chicago White Sox
0.524 103 54 49
18 Houston Astros
0.491 106 52 54

Chicago White Sox and Houston Astros Latest Matches

Chicago White Sox
Chicago White Sox Latest matches
W W L W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 22, 2026 - MLB

Texas Rangers
2 :  4
Chicago White Sox

Jul 21, 2026 - MLB

Texas Rangers
10 :  0
Chicago White Sox

Jul 20, 2026 - MLB

Texas Rangers
3 :  10
Chicago White Sox

Jul 19, 2026 - MLB

Toronto Blue Jays
0 :  3
Chicago White Sox
L W W W L L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 12, 2026 - MLB

Chicago White Sox
9 :  1
Athletics

Jul 11, 2026 - MLB

Chicago White Sox
1 :  0
Athletics

Jul 10, 2026 - MLB

Chicago White Sox
14 :  1
Athletics

Jul 9, 2026 - MLB

Chicago White Sox
1 :  2
Boston Red Sox
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 22, 2026 - MLB

Texas Rangers
2 :  4
Chicago White Sox

Jul 21, 2026 - MLB

Texas Rangers
10 :  0
Chicago White Sox

Jul 20, 2026 - MLB

Texas Rangers
3 :  10
Chicago White Sox

Jul 19, 2026 - MLB

Toronto Blue Jays
0 :  3
Chicago White Sox

Jul 18, 2026 - MLB

Toronto Blue Jays
1 :  0
Chicago White Sox

Jul 17, 2026 - MLB

Toronto Blue Jays
4 :  12
Chicago White Sox
Houston Astros
Houston Astros Latest matches
L W W W W W
Victories

5/6 (83%)

Defeats

1/6 (17%)

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 22, 2026 - MLB

Houston Astros
5 :  2
Miami Marlins

Jul 21, 2026 - MLB

Houston Astros
5 :  3
Miami Marlins

Jul 20, 2026 - MLB

Houston Astros
8 :  5
Miami Marlins

Jul 19, 2026 - MLB

Houston Astros
2 :  5
Baltimore Orioles
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 22, 2026 - MLB

Houston Astros
5 :  2
Miami Marlins

Jul 21, 2026 - MLB

Houston Astros
5 :  3
Miami Marlins

Jul 20, 2026 - MLB

Houston Astros
8 :  5
Miami Marlins

Jul 19, 2026 - MLB

Houston Astros
2 :  5
Baltimore Orioles

Jul 18, 2026 - MLB

Houston Astros
2 :  4
Baltimore Orioles

Jul 17, 2026 - MLB

Houston Astros
2 :  3
Baltimore Orioles
L L W L W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 12, 2026 - MLB

Texas Rangers
6 :  5
Houston Astros

Jul 11, 2026 - MLB

Texas Rangers
3 :  9
Houston Astros

Jul 10, 2026 - MLB

Texas Rangers
7 :  3
Houston Astros

Jul 8, 2026 - MLB

Washington Nationals
8 :  2
Houston Astros

Chicago White Sox against Houston Astros : Head to Head (H2H)

Chicago White Sox

17 %

Houston Astros

83 %

Jul 25, 2026 - MLB

Chicago White Sox
1 :  4
Houston Astros

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jun 12, 2025 - MLB

Houston Astros
4 :  3
Chicago White Sox

Jun 11, 2025 - MLB

Houston Astros
10 :  2
Chicago White Sox

May 4, 2025 - MLB

Chicago White Sox
5 :  4
Houston Astros

May 3, 2025 - MLB

Chicago White Sox
3 :  8
Houston Astros
Chicago White Sox vs Houston Astros Picks

Chicago White Sox - Houston Astros Key Points

  1. Houston are on a 5 game winning streak
  2. Chicago have lost 6 of their last 9 at home
  3. Houston have won their last 4 games against Chicago
  4. Houston have scored 27 runs in their last 4 games against Chicago
Up to $250 to bet on Chicago White Sox - Houston Astros! 

Limited Offer. Currently at Caesars Sportsbook

Our Chicago White Sox vs Houston Astros Prediction

The bookies have this as a coin flip game, but we think the Astros have a slight advantage on offense and will have the firepower required to complete the series sweep.

As Houston has demonstrated in the first two matchups of the series, they are capable of explosive scoring bursts that can completely flip a game on its head. That ability could prove crucial in what looks set to be a game of very fine margins. 

Our prediction for Chicago White Sox vs Houston Astros is: Astros to win. 

Prediction:

 

Astros to win

-118
$250 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.