Chicago White Sox vs Houston Astros Prediction & Picks - MLB

USA - MLB

Chicago White Sox
7/25/26 19:10
Houston Astros

Prediction:

 

The Astros will win

+105
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 by Lou Aguila | in MLB Picks

The Houston Astros, 3-0 in their last three games against the Chicago White Sox, target another upset on the road in Game 2 of their series.

Current Form:

Following Saturday’s 5-9 loss to the Houston Astros, the Chicago White Sox are 1-2 in their last 3 games, though they remain the No.1 team in the AL Central with a 54-48 record.

Meanwhile, the Astros have won their last four games, bumping up their record to 51-54, third in the AL West standings.

Starting Pitchers: White Sox RHP Sean Burke (7-3, 3.20 ERA) vs. Astros RHP Hunter Brown (7-4, 3.20 ERA).

The Matchup: The Astros have won their last three meetings with the White Sox and 6 of their last 10 games
Up to $250 to bet on Chicago White Sox - Houston Astros! 

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Chicago White Sox vs Houston Astros Form

Table

Teams Pts P W L
10 Chicago White Sox
0.521 117 61 56
12 Houston Astros
0.504 119 60 59

Chicago White Sox and Houston Astros Latest Matches

Chicago White Sox
Chicago White Sox Latest matches
L W W L W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 22, 2026 - MLB

Texas Rangers
2 :  4
Chicago White Sox

Jul 21, 2026 - MLB

Texas Rangers
10 :  0
Chicago White Sox

Jul 20, 2026 - MLB

Texas Rangers
3 :  10
Chicago White Sox

Jul 19, 2026 - MLB

Toronto Blue Jays
0 :  3
Chicago White Sox

Jul 18, 2026 - MLB

Toronto Blue Jays
1 :  0
Chicago White Sox
L L W W W L
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 12, 2026 - MLB

Chicago White Sox
9 :  1
Athletics

Jul 11, 2026 - MLB

Chicago White Sox
1 :  0
Athletics

Jul 10, 2026 - MLB

Chicago White Sox
14 :  1
Athletics

Jul 9, 2026 - MLB

Chicago White Sox
1 :  2
Boston Red Sox

Jul 8, 2026 - MLB

Chicago White Sox
0 :  5
Boston Red Sox
W L W W L W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 22, 2026 - MLB

Texas Rangers
2 :  4
Chicago White Sox

Jul 21, 2026 - MLB

Texas Rangers
10 :  0
Chicago White Sox

Jul 20, 2026 - MLB

Texas Rangers
3 :  10
Chicago White Sox

Jul 19, 2026 - MLB

Toronto Blue Jays
0 :  3
Chicago White Sox

Jul 18, 2026 - MLB

Toronto Blue Jays
1 :  0
Chicago White Sox

Jul 17, 2026 - MLB

Toronto Blue Jays
4 :  12
Chicago White Sox
Houston Astros
Houston Astros Latest matches
L L W W W W
Victories

4/6 (67%)

Defeats

2/6 (33%)

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 22, 2026 - MLB

Houston Astros
5 :  2
Miami Marlins

Jul 21, 2026 - MLB

Houston Astros
5 :  3
Miami Marlins

Jul 20, 2026 - MLB

Houston Astros
8 :  5
Miami Marlins

Jul 19, 2026 - MLB

Houston Astros
2 :  5
Baltimore Orioles

Jul 18, 2026 - MLB

Houston Astros
2 :  4
Baltimore Orioles
L L L W W W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 22, 2026 - MLB

Houston Astros
5 :  2
Miami Marlins

Jul 21, 2026 - MLB

Houston Astros
5 :  3
Miami Marlins

Jul 20, 2026 - MLB

Houston Astros
8 :  5
Miami Marlins

Jul 19, 2026 - MLB

Houston Astros
2 :  5
Baltimore Orioles

Jul 18, 2026 - MLB

Houston Astros
2 :  4
Baltimore Orioles

Jul 17, 2026 - MLB

Houston Astros
2 :  3
Baltimore Orioles
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jul 12, 2026 - MLB

Texas Rangers
6 :  5
Houston Astros

Jul 11, 2026 - MLB

Texas Rangers
3 :  9
Houston Astros

Jul 10, 2026 - MLB

Texas Rangers
7 :  3
Houston Astros

Jul 8, 2026 - MLB

Washington Nationals
8 :  2
Houston Astros

Jul 7, 2026 - MLB

Washington Nationals
3 :  6
Houston Astros

Chicago White Sox against Houston Astros : Head to Head (H2H)

Chicago White Sox

17 %

Houston Astros

83 %

Jul 24, 2026 - MLB

Chicago White Sox
5 :  9
Houston Astros

Jun 12, 2025 - MLB

Houston Astros
4 :  3
Chicago White Sox

Jun 11, 2025 - MLB

Houston Astros
10 :  2
Chicago White Sox

May 4, 2025 - MLB

Chicago White Sox
5 :  4
Houston Astros

May 3, 2025 - MLB

Chicago White Sox
3 :  8
Houston Astros

Aug 17, 2024 - MLB

Houston Astros
6 :  1
Chicago White Sox
Chicago White Sox vs Houston Astros Picks

Chicago White Sox - Houston Astros Key Points

  1. Houston is 8-4 SU in its last 12 games against Chicago White Sox.
  2. Houston is 4-1 SU in its last 5 games.
  3. Chicago is 0-3 vs. Houston in their last 3 games
  4. Hunter Brown has won his last three starts vs. the Chicago White Sox
Up to $250 to bet on Chicago White Sox - Houston Astros! 

Limited Offer. Currently at Caesars Sportsbook

Our Chicago White Sox vs Houston Astros Prediction

The Difference Maker: Hunter Brown might have posted a dismal 6.08 ERA over his last five outings, but the Astros pitcher is 3-0 in his last three starts against the White Sox. Brown has never allowed more than three runs in each of his last three meetings with Chicago.

What to Expect: Hunter Brown dominates the White Sox anew, taming the White Sox’s offense through seven innings. The Astros bullpen (2.38 ERA over the last five games) will finish the job by staving off any comeback bid from the White Sox.

Fearless Forecast: Astros 4, White Sox 2

Our betting prediction for the Houston Astros vs. the Chicago White Sox: The Astros will win

Prediction:

 

The Astros will win

+105
$250 offered for betting!

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All tips are fully researched and given in good faith, but profits cannot be guaranteed.