Baltimore Orioles vs Houston Astros Prediction & Picks - MLB

USA - MLB

Baltimore Orioles
4/30/26 12:35
Houston Astros

Prediction:

 

Over 7.5 runs.

-197
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 by Stephen Abiola | in MLB Picks

Baltimore Orioles (14-15) will look to extend their lead in this three-game series when they play Houston Astros (11-19) on Thursday evening at Oriole Park. The Orioles opened this series with a 5-3 win on Wednesday. Pete Alonso went deep with a two-run bomb in the fifth inning to give the O’s a 4-1 lead and put this contest to bed. However, they suffered a setback after their opening day starter, Trevor Rodgers, was added to the injury list with an undisclosed illness.

As for the Astros, it was another performance that highlighted the depleted state of their squad. They haven’t started the 2026 MLB season as they’d hoped due to their lengthy injury list. Core names like Hunter Brown, Jeremy Pena, and Tastuya Imai are nursing injuries. To be honest, any side would struggle without this group, which should’ve been Houston’s pitching backbone this season. However, their impressive offensive structure should win them matches.

Baltimore Orioles vs Houston Astros Form

Table

Teams Pts P W L
18 Houston Astros
0.482 85 41 44
22 Baltimore Orioles
0.464 84 39 45

Baltimore Orioles and Houston Astros Latest Matches

Baltimore Orioles
Baltimore Orioles Latest matches
L W W L L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 28, 2026 - MLB

Baltimore Orioles
5 :  3
Houston Astros

Apr 26, 2026 - MLB

Baltimore Orioles
3 :  5
Boston Red Sox

Apr 25, 2026 - MLB

Baltimore Orioles
1 :  17
Boston Red Sox

Apr 24, 2026 - MLB

Baltimore Orioles
10 :  3
Boston Red Sox

Apr 22, 2026 - MLB

Kansas City Royals
6 :  8
Baltimore Orioles

Apr 21, 2026 - MLB

Kansas City Royals
6 :  5
Baltimore Orioles
L L W L L W
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2026 - MLB

Baltimore Orioles
5 :  3
Houston Astros

Apr 26, 2026 - MLB

Baltimore Orioles
3 :  5
Boston Red Sox

Apr 25, 2026 - MLB

Baltimore Orioles
1 :  17
Boston Red Sox

Apr 24, 2026 - MLB

Baltimore Orioles
10 :  3
Boston Red Sox

Apr 15, 2026 - MLB

Baltimore Orioles
5 :  8
Arizona Diamondbacks

Apr 14, 2026 - MLB

Baltimore Orioles
3 :  4
Arizona Diamondbacks
W L L W L W
Victories

3/6 (50%)

Defeats

3/6 (50%)

Apr 22, 2026 - MLB

Kansas City Royals
6 :  8
Baltimore Orioles

Apr 21, 2026 - MLB

Kansas City Royals
6 :  5
Baltimore Orioles

Apr 20, 2026 - MLB

Kansas City Royals
5 :  7
Baltimore Orioles

Apr 19, 2026 - MLB

Cleveland Guardians
8 :  4
Baltimore Orioles

Apr 18, 2026 - MLB

Cleveland Guardians
4 :  2
Baltimore Orioles

Apr 17, 2026 - MLB

Cleveland Guardians
4 :  6
Baltimore Orioles
Houston Astros
Houston Astros Latest matches
L W L L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2026 - MLB

Baltimore Orioles
5 :  3
Houston Astros

Apr 26, 2026 - MLB

Houston Astros
7 :  4
New York Yankees

Apr 25, 2026 - MLB

Houston Astros
3 :  8
New York Yankees

Apr 24, 2026 - MLB

Houston Astros
4 :  12
New York Yankees

Apr 22, 2026 - MLB

Cleveland Guardians
0 :  2
Houston Astros

Apr 21, 2026 - MLB

Cleveland Guardians
8 :  5
Houston Astros
L L L L L W
Victories

1/6 (17%)

Defeats

5/6 (83%)

Apr 26, 2026 - MLB

Houston Astros
7 :  4
New York Yankees

Apr 25, 2026 - MLB

Houston Astros
3 :  8
New York Yankees

Apr 24, 2026 - MLB

Houston Astros
4 :  12
New York Yankees

Apr 19, 2026 - MLB

Houston Astros
5 :  7
St. Louis Cardinals

Apr 18, 2026 - MLB

Houston Astros
5 :  7
St. Louis Cardinals

Apr 17, 2026 - MLB

Houston Astros
4 :  9
St. Louis Cardinals
L L W L W L
Victories

2/6 (33%)

Defeats

4/6 (67%)

Apr 28, 2026 - MLB

Baltimore Orioles
5 :  3
Houston Astros

Apr 22, 2026 - MLB

Cleveland Guardians
0 :  2
Houston Astros

Apr 21, 2026 - MLB

Cleveland Guardians
8 :  5
Houston Astros

Apr 20, 2026 - MLB

Cleveland Guardians
2 :  9
Houston Astros

Apr 13, 2026 - MLB

Seattle Mariners
6 :  2
Houston Astros

Apr 12, 2026 - MLB

Seattle Mariners
6 :  1
Houston Astros

Baltimore Orioles against Houston Astros : Head to Head (H2H)

Baltimore Orioles

33 %

Houston Astros

67 %

Apr 28, 2026 - MLB

Baltimore Orioles
5 :  3
Houston Astros

Mar 10, 2026 - MLB Spring Training

Houston Astros
7 :  6
Baltimore Orioles

Mar 4, 2026 - MLB Spring Training

Baltimore Orioles
2 :  4
Houston Astros

Aug 24, 2025 - MLB

Baltimore Orioles
3 :  2
Houston Astros

Aug 23, 2025 - MLB

Baltimore Orioles
8 :  9
Houston Astros

Aug 22, 2025 - MLB

Baltimore Orioles
7 :  10
Houston Astros

Baltimore Orioles - Houston Astros Key Points

  1. The total runs went over in seven of the last eight Baltimore Orioles matches.
  2. The total runs went over in eight of the last 10 Houston Astros matches.
  3. The total runs went over 7.5 in the last eight Baltimore Orioles matches.
  4. The total runs went over 7.5 in four of the last five Houston Astros matches.

Our Baltimore Orioles vs Houston Astros Prediction

The Orioles are the warm -125 betting favorites. However, we’re backing the ‘Stros to make a comeback because of Chris Bassitt’s inconsistent form on the mound this season. The right-hander has gone 1-2 this season with an ERA of 6.75. He’ll need to do more to survive the five innings against the O’s, who boast a batting average of 2.60, which is fourth in baseball. The Astros also have 146 RBI this season, which is also fourth. However, the visitors are also struggling to keep opponents out, sitting at the bottom of the MBL standings with a 5.96 ERA. They’ll start Peter Lambert, who has a 1-1 record this year with a 3.27 ERA. He clearly gives the visitors an edge today.

Our prediction for Baltimore Orioles vs Houston Astros: Over 7.5 runs.

Prediction:

 

Over 7.5 runs.

-197
$200 offered for betting!

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Baltimore Orioles vs Houston Astros Picks