Baltimore Orioles vs Houston Astros Prediction & Picks - MLB
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by Stephen Abiola | in MLB Picks
Baltimore Orioles (14-15) will look to extend their lead in this three-game series when they play Houston Astros (11-19) on Thursday evening at Oriole Park. The Orioles opened this series with a 5-3 win on Wednesday. Pete Alonso went deep with a two-run bomb in the fifth inning to give the O’s a 4-1 lead and put this contest to bed. However, they suffered a setback after their opening day starter, Trevor Rodgers, was added to the injury list with an undisclosed illness.
As for the Astros, it was another performance that highlighted the depleted state of their squad. They haven’t started the 2026 MLB season as they’d hoped due to their lengthy injury list. Core names like Hunter Brown, Jeremy Pena, and Tastuya Imai are nursing injuries. To be honest, any side would struggle without this group, which should’ve been Houston’s pitching backbone this season. However, their impressive offensive structure should win them matches.
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Baltimore Orioles vs Houston Astros Form
Table
| Teams | Pts | P | W | L |
|---|---|---|---|---|
|
18
|
0.482 | 85 | 41 | 44 |
|
22
|
0.464 | 84 | 39 | 45 |
Baltimore Orioles and Houston Astros Latest Matches
3/6 (50%)
3/6 (50%)
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2/6 (33%)
4/6 (67%)
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3/6 (50%)
3/6 (50%)
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2/6 (33%)
4/6 (67%)
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1/6 (17%)
5/6 (83%)
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2/6 (33%)
4/6 (67%)
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Baltimore Orioles against Houston Astros : Head to Head (H2H)
33 %
67 %
Apr 28, 2026 - MLB
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Baltimore Orioles - Houston Astros Key Points
- The total runs went over in seven of the last eight Baltimore Orioles matches.
- The total runs went over in eight of the last 10 Houston Astros matches.
- The total runs went over 7.5 in the last eight Baltimore Orioles matches.
- The total runs went over 7.5 in four of the last five Houston Astros matches.
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Our Baltimore Orioles vs Houston Astros Prediction
The Orioles are the warm -125 betting favorites. However, we’re backing the ‘Stros to make a comeback because of Chris Bassitt’s inconsistent form on the mound this season. The right-hander has gone 1-2 this season with an ERA of 6.75. He’ll need to do more to survive the five innings against the O’s, who boast a batting average of 2.60, which is fourth in baseball. The Astros also have 146 RBI this season, which is also fourth. However, the visitors are also struggling to keep opponents out, sitting at the bottom of the MBL standings with a 5.96 ERA. They’ll start Peter Lambert, who has a 1-1 record this year with a 3.27 ERA. He clearly gives the visitors an edge today.
Our prediction for Baltimore Orioles vs Houston Astros: Over 7.5 runs.
All tips are fully researched and given in good faith, but profits cannot be guaranteed.