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by Paul Tamayo in NBA Picks
The Golden State Warriors visit the Los Angeles Lakers in an NBA 2025-26 game on Tuesday, October 21, at the Crypto.com Arena.
Two Western Conference contenders go at it on opening night, with the Lakers hosting Stephen Curry and the Warriors. However, the purple-and-gold will be shorthanded heading into this matchup against their conference rivals.
LeBron James, who is entering his 23rd season in the NBA, is currently sidelined with sciatica on his right side. The four-time MVP averaged 24.4 points, 7.8 rebounds, and 8.2 assists last season, while logging 34.9 minutes, his lowest in the last four years.
It means that Lakers head coach JJ Redick might field a starting five of Luka Doncic, Gabe Vincent, Austin Reaves, Rui Hachimura, and Deandre Ayton. Veteran guard Marcus Smart is another new face who could log significant minutes.
Meanwhile, the Warriors also reeled in an important veteran presence in Al Horford. There's no certainty yet on who Steve Kerr will start, but signs point to Horford joining Curry, Jimmy Butler, Draymond Green, and either Brandin Podziemski or Jonathan Kuminga.
Moses Moody was expected to be in that starting five, but he sustained a calf injury that will keep him out for the Lakers game.
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Golden State Warriors vs Los Angeles Lakers Form
Golden State Warriors and Los Angeles Lakers Latest Matches

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Golden State Warriors against Los Angeles Lakers : Head to Head (H2H)
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Golden State Warriors - Los Angeles Lakers Key Points
- The Lakers are expected to start Luka Doncic, Gabe Vincent, Austin Reaves, Rui Hachimura, and Deandre Ayton.
- The Warriors are expected to start Steph Curry, Brandin Podziemski, Jimmy Butler, Draymond Green, and Al Horford.
- The Lakers will miss the services of LeBron James (sciatica).
- The Warriors will miss the services of Moses Moody (calf).
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Our Golden State Warriors vs Los Angeles Lakers Prediction
It's an explosive opening game as the Lakers take on the visiting Warriors. Despite the absence of the injured LeBron James, Laker fans are excited to see a full year of Luka Doncic in their camp.
As for the Warriors, they shored up their frontline with the acquisition of veteran Al Horford. But this is a relatively older squad, so let's see if there's enough gas in their tank this season. Our prediction for the Los Angeles Lakers vs Golden State Warriors match is: Warriors (-2.5) cover the spread.Grab an extra $300 for your Golden State Warriors vs Los Angeles Lakers wager!
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All tips are fully researched and given in good faith, but profits cannot be guaranteed.
